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The map label for this gene is ylaB [H]

Identifier: 218549874

GI number: 218549874

Start: 2625452

End: 2627002

Strand: Direct

Name: ylaB [H]

Synonym: EFER_2559

Alternate gene names: 218549874

Gene position: 2625452-2627002 (Clockwise)

Preceding gene: 218549873

Following gene: 218549877

Centisome position: 57.22

GC content: 45.65

Gene sequence:

>1551_bases
GTGAGAACTCGTCATCTGATTAGCCTTGTTACAGGCGTGCTCATTTTGTCCGTGATTGTTCCAGTCGGCTTAATCCTTTG
GCTTGCTCACCGTCAGGTTGAAAGTACATTTATTGACGAGCTAAATATTTACGCCTCACGCGTCAATCTACGGGCTGAAA
AAGTTGCTTCCCAGGGCAAAAGAGCACTGGAACAACTGGAAGCATTTCAGGGCCCCCCTTGTAGCCCTGAGCAATTGATG
GAAATGCGCCGGGTTTCTTACAGTTTTCGCTATATTCAGGAAGTCCTTTATATCAACAATAACGTTCCGCTCTGCTCTTC
ACTGGAACAAAATAGCGCCCCGATTGCTTTCCCGGCACCGGGGAAAATCACCCGTGAAGGTTATCGGGTCTGGTTAACGG
AAGAAAATGACCTTGGCTTAAAACGTTATATGGTTGCCATCGGCACCCAACACTATGTGGTGATGATCGATCCTGCTTCC
TTTATCGATGTTATTCCCTTCAGCAGCTGGCGTATCAATGCAGCGATCATCGGTGAAGCTCATCATGTGGTGATTTCAGG
TAGTGAACAACTGCCTCCTGATGTAGTTGCACTGTTAAAAAACACGGGTAACCAACATCTGGAAATAGACAACACCATCT
ATAATATTCAGTCTTTTCCTGAAATGAATATTTCTATCATCACCTGGTCTTCTACACTCCCTTTGCAAAAAAGCTGGCAT
CACGAAACGCTTATTTGGCTACCTTTAGGACTGTTGATTGGCGTACTCTCTGCACTGTTTATTTTGCGCATTGTCCGACG
ATTACAGTCTCCCCATCATCGATTGCAGGACGCGATCAATAATGGCGATATAAAAGTGCATTATCAGCCAATCGTCTCTT
TGACAACCGGTAAAATTGTGGGTGCTGAAGCACTGGCCCGCTGGCCACAAACCGACGGTACTTACCTTTCCCCGGAAGTC
TTTATTCCTCTCGCCCAACAAACCGGTCTTTTGGAATCGATGACTCATCTGGTCATTAAAACAGTATTTGAAGATATGGG
AGTGTGGCTGAATCAACACCCGGAGCAACATATCTCTATCAATCTGGAATCTTCCGTTCTGGCCTCGGAAAAAATTCCAC
AGCTATTAGGAAGAATGCTTAATCATTACAAAGTTAACCCTAATCAAATCGCCCTTGAACTGACAGAGCGCGAGTTTGCC
GATCCCAAAACCAGTGCTCCGCTAATTGCCGGATACCGCAAAGCGGGGCATGAAATTTATATTGATGATTTCGGCACCGG
TTACTCCAGTCTGAGTTACTTGCAAAATCTTGATGTCGATATTCTTAAGATCGATAAATCTTTCGTGGATGCCCTGGAAT
ATAAAAATGTCACCACGCATATTGTTGAGATGGCAAAAACGTTAAAGCTAAAAATGGTCGCGGAAGGTATTGAAACCCCT
CATCAGGAGAGCTGGTTACGCCAGCATGGCGTGCACTACGGCCAGGGCTGGCTCTACAGCAAGGCATTACCGAAAGAGGA
TTTCTTACGCTGGGCCGAGCAACATTTGTGA

Upstream 100 bases:

>100_bases
TTTACCCTCAGCTGTCTTATGCATTAACTCAATAACATTCGCGAAGCTTATCTATTGATGAGATATACTTTCTCTACTCT
GCGTAAATAAGGATATCTTC

Downstream 100 bases:

>100_bases
ATTGTTGGGCTGACGGCACGCCGCACAGCCCGTCACGCTACCTATTCGTCGATGATTGACTCGAATCCGCCATAGATCAT
TCGCTTGCCATCAAACGGCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MRTRHLISLVTGVLILSVIVPVGLILWLAHRQVESTFIDELNIYASRVNLRAEKVASQGKRALEQLEAFQGPPCSPEQLM
EMRRVSYSFRYIQEVLYINNNVPLCSSLEQNSAPIAFPAPGKITREGYRVWLTEENDLGLKRYMVAIGTQHYVVMIDPAS
FIDVIPFSSWRINAAIIGEAHHVVISGSEQLPPDVVALLKNTGNQHLEIDNTIYNIQSFPEMNISIITWSSTLPLQKSWH
HETLIWLPLGLLIGVLSALFILRIVRRLQSPHHRLQDAINNGDIKVHYQPIVSLTTGKIVGAEALARWPQTDGTYLSPEV
FIPLAQQTGLLESMTHLVIKTVFEDMGVWLNQHPEQHISINLESSVLASEKIPQLLGRMLNHYKVNPNQIALELTEREFA
DPKTSAPLIAGYRKAGHEIYIDDFGTGYSSLSYLQNLDVDILKIDKSFVDALEYKNVTTHIVEMAKTLKLKMVAEGIETP
HQESWLRQHGVHYGQGWLYSKALPKEDFLRWAEQHL

Sequences:

>Translated_516_residues
MRTRHLISLVTGVLILSVIVPVGLILWLAHRQVESTFIDELNIYASRVNLRAEKVASQGKRALEQLEAFQGPPCSPEQLM
EMRRVSYSFRYIQEVLYINNNVPLCSSLEQNSAPIAFPAPGKITREGYRVWLTEENDLGLKRYMVAIGTQHYVVMIDPAS
FIDVIPFSSWRINAAIIGEAHHVVISGSEQLPPDVVALLKNTGNQHLEIDNTIYNIQSFPEMNISIITWSSTLPLQKSWH
HETLIWLPLGLLIGVLSALFILRIVRRLQSPHHRLQDAINNGDIKVHYQPIVSLTTGKIVGAEALARWPQTDGTYLSPEV
FIPLAQQTGLLESMTHLVIKTVFEDMGVWLNQHPEQHISINLESSVLASEKIPQLLGRMLNHYKVNPNQIALELTEREFA
DPKTSAPLIAGYRKAGHEIYIDDFGTGYSSLSYLQNLDVDILKIDKSFVDALEYKNVTTHIVEMAKTLKLKMVAEGIETP
HQESWLRQHGVHYGQGWLYSKALPKEDFLRWAEQHL
>Mature_516_residues
MRTRHLISLVTGVLILSVIVPVGLILWLAHRQVESTFIDELNIYASRVNLRAEKVASQGKRALEQLEAFQGPPCSPEQLM
EMRRVSYSFRYIQEVLYINNNVPLCSSLEQNSAPIAFPAPGKITREGYRVWLTEENDLGLKRYMVAIGTQHYVVMIDPAS
FIDVIPFSSWRINAAIIGEAHHVVISGSEQLPPDVVALLKNTGNQHLEIDNTIYNIQSFPEMNISIITWSSTLPLQKSWH
HETLIWLPLGLLIGVLSALFILRIVRRLQSPHHRLQDAINNGDIKVHYQPIVSLTTGKIVGAEALARWPQTDGTYLSPEV
FIPLAQQTGLLESMTHLVIKTVFEDMGVWLNQHPEQHISINLESSVLASEKIPQLLGRMLNHYKVNPNQIALELTEREFA
DPKTSAPLIAGYRKAGHEIYIDDFGTGYSSLSYLQNLDVDILKIDKSFVDALEYKNVTTHIVEMAKTLKLKMVAEGIETP
HQESWLRQHGVHYGQGWLYSKALPKEDFLRWAEQHL

Specific function: Unknown

COG id: COG4943

COG function: function code T; Predicted signal transduction protein containing sensor and EAL domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI87081743, Length=516, Percent_Identity=74.6124031007752, Blast_Score=813, Evalue=0.0,
Organism=Escherichia coli, GI1790496, Length=523, Percent_Identity=33.2695984703633, Blast_Score=285, Evalue=4e-78,
Organism=Escherichia coli, GI87081845, Length=269, Percent_Identity=35.3159851301115, Blast_Score=155, Evalue=7e-39,
Organism=Escherichia coli, GI1788502, Length=340, Percent_Identity=29.4117647058824, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI226510982, Length=237, Percent_Identity=34.1772151898734, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI87081921, Length=243, Percent_Identity=34.156378600823, Blast_Score=132, Evalue=8e-32,
Organism=Escherichia coli, GI1787541, Length=247, Percent_Identity=29.9595141700405, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI87081980, Length=242, Percent_Identity=34.7107438016529, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786507, Length=241, Percent_Identity=33.195020746888, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI87082096, Length=242, Percent_Identity=32.6446280991736, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788849, Length=258, Percent_Identity=29.0697674418605, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1787055, Length=306, Percent_Identity=26.797385620915, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787410, Length=229, Percent_Identity=25.764192139738, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 58458; Mature: 58458

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTRHLISLVTGVLILSVIVPVGLILWLAHRQVESTFIDELNIYASRVNLRAEKVASQGK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RALEQLEAFQGPPCSPEQLMEMRRVSYSFRYIQEVLYINNNVPLCSSLEQNSAPIAFPAP
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCC
GKITREGYRVWLTEENDLGLKRYMVAIGTQHYVVMIDPASFIDVIPFSSWRINAAIIGEA
CCEECCCEEEEEECCCCCCHHHHHHHCCCCEEEEEECCHHHHHHCCCCCEEEEEEEECCC
HHVVISGSEQLPPDVVALLKNTGNQHLEIDNTIYNIQSFPEMNISIITWSSTLPLQKSWH
EEEEEECCCCCCHHHHHHHHCCCCCEEEECCEEEECCCCCCCCEEEEEECCCCCCCCCCC
HETLIWLPLGLLIGVLSALFILRIVRRLQSPHHRLQDAINNGDIKVHYQPIVSLTTGKIV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEEEEEEEECCCEE
GAEALARWPQTDGTYLSPEVFIPLAQQTGLLESMTHLVIKTVFEDMGVWLNQHPEQHISI
CHHHHHCCCCCCCCEECCCEEEECHHHCCHHHHHHHHHHHHHHHHHCHHHHCCCCCCEEE
NLESSVLASEKIPQLLGRMLNHYKVNPNQIALELTEREFADPKTSAPLIAGYRKAGHEIY
EEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHCCCCCCCCCHHHHHHHCCCEEE
IDDFGTGYSSLSYLQNLDVDILKIDKSFVDALEYKNVTTHIVEMAKTLKLKMVAEGIETP
EECCCCCHHHHHHHHCCCCEEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
HQESWLRQHGVHYGQGWLYSKALPKEDFLRWAEQHL
CHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRTRHLISLVTGVLILSVIVPVGLILWLAHRQVESTFIDELNIYASRVNLRAEKVASQGK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RALEQLEAFQGPPCSPEQLMEMRRVSYSFRYIQEVLYINNNVPLCSSLEQNSAPIAFPAP
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCC
GKITREGYRVWLTEENDLGLKRYMVAIGTQHYVVMIDPASFIDVIPFSSWRINAAIIGEA
CCEECCCEEEEEECCCCCCHHHHHHHCCCCEEEEEECCHHHHHHCCCCCEEEEEEEECCC
HHVVISGSEQLPPDVVALLKNTGNQHLEIDNTIYNIQSFPEMNISIITWSSTLPLQKSWH
EEEEEECCCCCCHHHHHHHHCCCCCEEEECCEEEECCCCCCCCEEEEEECCCCCCCCCCC
HETLIWLPLGLLIGVLSALFILRIVRRLQSPHHRLQDAINNGDIKVHYQPIVSLTTGKIV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEEEEEEEECCCEE
GAEALARWPQTDGTYLSPEVFIPLAQQTGLLESMTHLVIKTVFEDMGVWLNQHPEQHISI
CHHHHHCCCCCCCCEECCCEEEECHHHCCHHHHHHHHHHHHHHHHHCHHHHCCCCCCEEE
NLESSVLASEKIPQLLGRMLNHYKVNPNQIALELTEREFADPKTSAPLIAGYRKAGHEIY
EEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHCCCCCCCCCHHHHHHHCCCEEE
IDDFGTGYSSLSYLQNLDVDILKIDKSFVDALEYKNVTTHIVEMAKTLKLKMVAEGIETP
EECCCCCHHHHHHHHCCCCEEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
HQESWLRQHGVHYGQGWLYSKALPKEDFLRWAEQHL
CHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]