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The map label for this gene is hinT [H]

Identifier: 218549171

GI number: 218549171

Start: 1878760

End: 1879119

Strand: Reverse

Name: hinT [H]

Synonym: EFER_1825

Alternate gene names: 218549171

Gene position: 1879119-1878760 (Counterclockwise)

Preceding gene: 218549172

Following gene: 218549170

Centisome position: 40.95

GC content: 48.89

Gene sequence:

>360_bases
GTGGCAGAAGAGACAATATTCAGCAAAATTATTCGTCGTGAAATCCCCTCCGATATCGTATATCAGGACGATCTGGTGAC
CGCATTTCGCGATATCTCACCGCAGGCTCCTACCCATATTTTAATCATCCCTAACATTCTGATCCCCACGGTTAATGACG
TTACCGCTGAGCACGAACAGGCGTTGGGGCGCATGATTACCGTCGCAGCGAAAATTGCCGAACAGGAAGGTATTGCCGAG
GATGGTTATCGCTTAATCATGAATACCAATCGTCATGGCGGGCAAGAGGTGTACCATATTCATATGCATCTGCTCGGTGG
ACGAGCCCTCGGCCCAATGTTGGCACATAAAGGTCTGTAA

Upstream 100 bases:

>100_bases
AAGGTTGAAAGGGCGGGAAGAAGTCGCTCATACTCTATACTCGCATTATGGTTAGCGTAGCATGGCGCAACGCAGTGACT
CTTTGAAGAAGGAAAATGTC

Downstream 100 bases:

>100_bases
TAATGTCCAGAGGATGCATTGCGCTATCTGTGATTTTTATGCTTCTGGCGGGCTGCCGATCGCATCCGGAAATTCCGGTT
AATGACGAGCAGACGCTGGT

Product: purine nucleoside phosphoramidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 119; Mature: 118

Protein sequence:

>119_residues
MAEETIFSKIIRREIPSDIVYQDDLVTAFRDISPQAPTHILIIPNILIPTVNDVTAEHEQALGRMITVAAKIAEQEGIAE
DGYRLIMNTNRHGGQEVYHIHMHLLGGRALGPMLAHKGL

Sequences:

>Translated_119_residues
MAEETIFSKIIRREIPSDIVYQDDLVTAFRDISPQAPTHILIIPNILIPTVNDVTAEHEQALGRMITVAAKIAEQEGIAE
DGYRLIMNTNRHGGQEVYHIHMHLLGGRALGPMLAHKGL
>Mature_118_residues
AEETIFSKIIRREIPSDIVYQDDLVTAFRDISPQAPTHILIIPNILIPTVNDVTAEHEQALGRMITVAAKIAEQEGIAED
GYRLIMNTNRHGGQEVYHIHMHLLGGRALGPMLAHKGL

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI14211923, Length=109, Percent_Identity=46.7889908256881, Blast_Score=115, Evalue=8e-27,
Organism=Homo sapiens, GI4885413, Length=107, Percent_Identity=47.6635514018692, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787346, Length=119, Percent_Identity=98.3193277310924, Blast_Score=238, Evalue=6e-65,
Organism=Caenorhabditis elegans, GI17506713, Length=109, Percent_Identity=44.0366972477064, Blast_Score=111, Evalue=7e-26,
Organism=Drosophila melanogaster, GI28574010, Length=109, Percent_Identity=44.954128440367, Blast_Score=112, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24581222, Length=109, Percent_Identity=44.954128440367, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 13230; Mature: 13098

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEETIFSKIIRREIPSDIVYQDDLVTAFRDISPQAPTHILIIPNILIPTVNDVTAEHEQ
CCHHHHHHHHHHHHCCCCCEECHHHHHHHHHCCCCCCEEEEEECCEECCCCCCHHHHHHH
ALGRMITVAAKIAEQEGIAEDGYRLIMNTNRHGGQEVYHIHMHLLGGRALGPMLAHKGL
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEEEHHCCCHHHHHHHCCCC
>Mature Secondary Structure 
AEETIFSKIIRREIPSDIVYQDDLVTAFRDISPQAPTHILIIPNILIPTVNDVTAEHEQ
CHHHHHHHHHHHHCCCCCEECHHHHHHHHHCCCCCCEEEEEECCEECCCCCCHHHHHHH
ALGRMITVAAKIAEQEGIAEDGYRLIMNTNRHGGQEVYHIHMHLLGGRALGPMLAHKGL
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEEEHHCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]