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The map label for this gene is mppA [H]

Identifier: 218548999

GI number: 218548999

Start: 1694232

End: 1695845

Strand: Reverse

Name: mppA [H]

Synonym: EFER_1647

Alternate gene names: 218548999

Gene position: 1695845-1694232 (Counterclockwise)

Preceding gene: 218549001

Following gene: 218548997

Centisome position: 36.96

GC content: 45.85

Gene sequence:

>1614_bases
ATGAGGCACTCTGTTTCAGTAACGTGTTGTGCGCTGTTGGTTAGCAGCATTTCTTTGTCCTGGGCGGCAGATGTTCCCGA
TGGAACAGTGCTCGCAAAGAAGCAAGAGATTGTGCGCCATATCAAGGATGAGCCAGCGACATTAGACCCGGCGAAAGCGG
TAGGATTACCCGAGATTCAGGTTATCCGGGACCTGTTTGAAGGGCTGGTTAATCAGAATGAGAAGGGGGAAATTGTTCCC
GGTGTTGCTACTCAGTGGAAAAGCAACGACAACCGTATCTGGACTTTTACCCTGCGTGATGACGCAAAATGGGCTGATGG
TACGCCAGTGACTGCGGAAGATTTTGTTTATAGTTGGCAGCGACTGGTTGACCCGAAGACATTATCTCCCTTTGCCTGGT
TTGCTGCACTTGCCGGAATTAACAATGCTCAGGCGATAATCGACGGTAAAACCACACCAGATAAACTGGGGGTAACAGCC
GTTGATGCCCGTACACTTAAAGTGCATCTCGATAAGCCATTACCGTGGTTTGCTAATTTAACCGCCAGTTTTGCTTTTTA
TCCGGTAAAAAAAGCGAATGTAGAAAGTGGCAAAGAGTGGACAAAGCCTGGCAATTTAGTTGGTAATGGCGCGTTTGTGT
TAAAAGAGCGGGTGGTCAACGAAAAACTGGTTGTTGTTCCTAATAGCCACTACTGGGATAACGGTAAAACGGTGCTGCAA
AAAGTCACTTTCCTGCCAATCAATCAGGAGTCTGCCGCAACAAAACGTTATCTGGCCGGTGATATTGATATCACCGAGTC
GTTCCCGAAAAATCTCTACCAAAAATTGCTGAAGGATATTCCGGGGCAGGTTTATACACCGCCGCAGTTAGGTACTTACT
ATTATGCGTTTAATACTCAGAAGGGGCCAACTGCGGATCAACGTGTCCGTATGGCGCTGAGTATGACTATCGACAGACGT
CTGATTGCAGAAAAAGTACTGGGTACAGGTGAAAAACCGGCATGGCATTTTACCCCTGATGTTACCGCAGGATTTACACC
TGAACCTTCGCCATTTGAGCAGATGAGCCAGGAAGAACTCAATGCACAGGCAAAAACATTGCTGAGTGCGGCAGGTTATG
GCCCTCAAAAACCGCTCAAACTGACACTGCTGTATAACACTTCTGAGAATCACCAGAAGATCGCGATTGCGGTCGCGTCA
ATGTGGAAAAAGAATCTCGGCGTTGATGTTAAACTGCAAAATCAGGAATGGAAAACCTATATTGATAGCCGTAATACCGG
CAATTTTGATGTCATCCGCGCTTCTTGGGTAGGCGATTATAATGAACCGTCAACTTTCCTGTCATTGTTAACCTCAATGC
ACTCAGGCAATATTTCACGGTTTAATAATCCGGCTTATGACAAGGTAATTAATCAGGCTTCGCTGGAGAATACAGAAAAG
GCAAGGAATGCTGATTATAATTCTGCGGAAAAAATATTGATGGAGCAGGCACCTATTGCACCAATCTATCAGTACACTAA
TGGTCGATTAATTAAACCGTGGCTGAAAGGTTATCCGATCAACAATGCAGAAGATGTTGCCTACAGCCGCACAATGTATG
TTGTTGAGCACTGA

Upstream 100 bases:

>100_bases
TTACGTGTCATATCAATTTTTTATTACAAGGTATTTGCAATTCTTTAAGGCGAAACAAATAATTACGCATCTAAATAAAA
GCCGGATTGAGGGAACCCAG

Downstream 100 bases:

>100_bases
TATACTCGTTGCAGGTGCTGCGACTCGAATTATTTAGTGTAGACATCTTTCAAAGTAAAACTGGCGCATTTGGGCGCCAG
TTTTTCTAGACAAAATTAAC

Product: murein tripeptide ABC transporter periplasmic-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 537

Protein sequence:

>537_residues
MRHSVSVTCCALLVSSISLSWAADVPDGTVLAKKQEIVRHIKDEPATLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIVP
GVATQWKSNDNRIWTFTLRDDAKWADGTPVTAEDFVYSWQRLVDPKTLSPFAWFAALAGINNAQAIIDGKTTPDKLGVTA
VDARTLKVHLDKPLPWFANLTASFAFYPVKKANVESGKEWTKPGNLVGNGAFVLKERVVNEKLVVVPNSHYWDNGKTVLQ
KVTFLPINQESAATKRYLAGDIDITESFPKNLYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPTADQRVRMALSMTIDRR
LIAEKVLGTGEKPAWHFTPDVTAGFTPEPSPFEQMSQEELNAQAKTLLSAAGYGPQKPLKLTLLYNTSENHQKIAIAVAS
MWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLSLLTSMHSGNISRFNNPAYDKVINQASLENTEK
ARNADYNSAEKILMEQAPIAPIYQYTNGRLIKPWLKGYPINNAEDVAYSRTMYVVEH

Sequences:

>Translated_537_residues
MRHSVSVTCCALLVSSISLSWAADVPDGTVLAKKQEIVRHIKDEPATLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIVP
GVATQWKSNDNRIWTFTLRDDAKWADGTPVTAEDFVYSWQRLVDPKTLSPFAWFAALAGINNAQAIIDGKTTPDKLGVTA
VDARTLKVHLDKPLPWFANLTASFAFYPVKKANVESGKEWTKPGNLVGNGAFVLKERVVNEKLVVVPNSHYWDNGKTVLQ
KVTFLPINQESAATKRYLAGDIDITESFPKNLYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPTADQRVRMALSMTIDRR
LIAEKVLGTGEKPAWHFTPDVTAGFTPEPSPFEQMSQEELNAQAKTLLSAAGYGPQKPLKLTLLYNTSENHQKIAIAVAS
MWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLSLLTSMHSGNISRFNNPAYDKVINQASLENTEK
ARNADYNSAEKILMEQAPIAPIYQYTNGRLIKPWLKGYPINNAEDVAYSRTMYVVEH
>Mature_537_residues
MRHSVSVTCCALLVSSISLSWAADVPDGTVLAKKQEIVRHIKDEPATLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIVP
GVATQWKSNDNRIWTFTLRDDAKWADGTPVTAEDFVYSWQRLVDPKTLSPFAWFAALAGINNAQAIIDGKTTPDKLGVTA
VDARTLKVHLDKPLPWFANLTASFAFYPVKKANVESGKEWTKPGNLVGNGAFVLKERVVNEKLVVVPNSHYWDNGKTVLQ
KVTFLPINQESAATKRYLAGDIDITESFPKNLYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPTADQRVRMALSMTIDRR
LIAEKVLGTGEKPAWHFTPDVTAGFTPEPSPFEQMSQEELNAQAKTLLSAAGYGPQKPLKLTLLYNTSENHQKIAIAVAS
MWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLSLLTSMHSGNISRFNNPAYDKVINQASLENTEK
ARNADYNSAEKILMEQAPIAPIYQYTNGRLIKPWLKGYPINNAEDVAYSRTMYVVEH

Specific function: Essential for the uptake of the murein peptide L-alanyl- gamma-D-glutamyl-meso-diaminopimelate. Also transports some alpha- linked peptides such as Pro-Phe-Lys with low affinity. The transport is effected by the oligopeptide permease system [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI87081878, Length=537, Percent_Identity=93.2960893854749, Blast_Score=1053, Evalue=0.0,
Organism=Escherichia coli, GI1787495, Length=531, Percent_Identity=47.4576271186441, Blast_Score=494, Evalue=1e-141,
Organism=Escherichia coli, GI1789397, Length=529, Percent_Identity=43.1001890359168, Blast_Score=406, Evalue=1e-114,
Organism=Escherichia coli, GI1787762, Length=536, Percent_Identity=27.6119402985075, Blast_Score=152, Evalue=8e-38,
Organism=Escherichia coli, GI1789887, Length=474, Percent_Identity=24.8945147679325, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789966, Length=466, Percent_Identity=22.7467811158798, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59958; Mature: 59958

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHSVSVTCCALLVSSISLSWAADVPDGTVLAKKQEIVRHIKDEPATLDPAKAVGLPEIQ
CCCCCHHHHHHHHHHHCCCEEECCCCCCCEEHHHHHHHHHHCCCCCCCCHHHHCCCCHHH
VIRDLFEGLVNQNEKGEIVPGVATQWKSNDNRIWTFTLRDDAKWADGTPVTAEDFVYSWQ
HHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHH
RLVDPKTLSPFAWFAALAGINNAQAIIDGKTTPDKLGVTAVDARTLKVHLDKPLPWFANL
HHCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHCCEEEECCEEEEEEECCCCCHHHHH
TASFAFYPVKKANVESGKEWTKPGNLVGNGAFVLKERVVNEKLVVVPNSHYWDNGKTVLQ
HHHEEEEEEECCCCCCCCCCCCCCCEECCCHHEEHHHHCCCEEEEECCCCEECCCHHHHH
KVTFLPINQESAATKRYLAGDIDITESFPKNLYQKLLKDIPGQVYTPPQLGTYYYAFNTQ
EEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEECC
KGPTADQRVRMALSMTIDRRLIAEKVLGTGEKPAWHFTPDVTAGFTPEPSPFEQMSQEEL
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHH
NAQAKTLLSAAGYGPQKPLKLTLLYNTSENHQKIAIAVASMWKKNLGVDVKLQNQEWKTY
HHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEHHHHHHHHCCCEEEEECCCHHHHH
IDSRNTGNFDVIRASWVGDYNEPSTFLSLLTSMHSGNISRFNNPAYDKVINQASLENTEK
HCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCHHHH
ARNADYNSAEKILMEQAPIAPIYQYTNGRLIKPWLKGYPINNAEDVAYSRTMYVVEH
HCCCCCCHHHHHHHHCCCCCCEEEECCCEEECHHHCCCCCCCHHHHEEEEEEEEEEC
>Mature Secondary Structure
MRHSVSVTCCALLVSSISLSWAADVPDGTVLAKKQEIVRHIKDEPATLDPAKAVGLPEIQ
CCCCCHHHHHHHHHHHCCCEEECCCCCCCEEHHHHHHHHHHCCCCCCCCHHHHCCCCHHH
VIRDLFEGLVNQNEKGEIVPGVATQWKSNDNRIWTFTLRDDAKWADGTPVTAEDFVYSWQ
HHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHH
RLVDPKTLSPFAWFAALAGINNAQAIIDGKTTPDKLGVTAVDARTLKVHLDKPLPWFANL
HHCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHCCEEEECCEEEEEEECCCCCHHHHH
TASFAFYPVKKANVESGKEWTKPGNLVGNGAFVLKERVVNEKLVVVPNSHYWDNGKTVLQ
HHHEEEEEEECCCCCCCCCCCCCCCEECCCHHEEHHHHCCCEEEEECCCCEECCCHHHHH
KVTFLPINQESAATKRYLAGDIDITESFPKNLYQKLLKDIPGQVYTPPQLGTYYYAFNTQ
EEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEECC
KGPTADQRVRMALSMTIDRRLIAEKVLGTGEKPAWHFTPDVTAGFTPEPSPFEQMSQEEL
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHH
NAQAKTLLSAAGYGPQKPLKLTLLYNTSENHQKIAIAVASMWKKNLGVDVKLQNQEWKTY
HHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEHHHHHHHHCCCEEEEECCCHHHHH
IDSRNTGNFDVIRASWVGDYNEPSTFLSLLTSMHSGNISRFNNPAYDKVINQASLENTEK
HCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCHHHH
ARNADYNSAEKILMEQAPIAPIYQYTNGRLIKPWLKGYPINNAEDVAYSRTMYVVEH
HCCCCCCHHHHHHHHCCCCCCEEEECCCEEECHHHCCCCCCCHHHHEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9495761; 9097039; 9278503 [H]