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The map label for this gene is paaK [H]

Identifier: 218548950

GI number: 218548950

Start: 1642684

End: 1643997

Strand: Reverse

Name: paaK [H]

Synonym: EFER_1598

Alternate gene names: 218548950

Gene position: 1643997-1642684 (Counterclockwise)

Preceding gene: 218548951

Following gene: 218548949

Centisome position: 35.83

GC content: 51.83

Gene sequence:

>1314_bases
ATGATAACCAATACAAAGCTTGACCCGATTGAAACCGCGTCTGTTGATGAGTTACAGGCGTTGCAAACACAGCGTCTGAA
ATGGACGCTCAAACACGCGTATGAAAATGTGCCGATGTATCGGCGAAAATTCGACGCAGCAGGTGTACATCCTGATGATT
TCAGGGAACTTTCAGACCTGCGTAAATTTCCCTGTACCACCAAGCAGGATCTGCGCGACAACTATCCCTTTGACACCTTT
GCCGTGCCGATGGAACAAGTGGTGCGCATTCATGCTTCTTCGGGAACCACAGGTAAACCGACAGTTGTCGGCTATACACA
AAACGATATTGATAACTGGGCCAATATCGTAGCGCGTTCCTTGCGTGCGGCAGGTGGCACGCCCAAAGACAAAATTCATG
TCGCCTATGGTTACGGCCTGTTTACCGGTGGGCTGGGCGCGCACTATGGTGCAGAACGCCTGGGCGCTACGGTGATCCCG
ATGTCTGGCGGGCAGACGGAAAAACAAGCGCAACTGATCCGCGATTTTCAACCGGATATGATCATGGTTACGCCATCTTA
TTGCCTTAACCTGATTGAAGAGCTGGAACGGCAGTTGGGCGGTGATGCCAGCGGTTGCTCGCTGCGAGTTGGAGTGTTTG
GTGCTGAGCCGTGGACACAGGCCATGCGTAAAGAGATTGAACGGCGTCTGGGGATCACTGCGCTGGATATTTATGGCCTG
TCAGAAGTGATGGGGCCGGGGGTCGCGATGGAGTGTCTGGAAACTACCGACGGCCCAACCATTTGGGAAGATCATTTCTA
TCCTGAAATTGTTAATCCCAATGACGGCACACCGCTTGCCGATGGCGAACATGGCGAACTGTTATTCACCACGCTGACCA
AAGAAGCATTGCCGGTTATTCGTTACCGTACGCGTGATTTAACCCGACTGTTGCCAGGAACGGCACGAACCATGCGCCGC
ATGGATCGCATCAGTGGACGTAGCGATGACATGTTGATCATTCGCGGTGTAAATGTCTTCCCGTCACAACTGGAAGAAGA
GATTGTCAAATTCGAACATTTATCGCCGCATTACCAACTGGAGGTTAACCGTCGGGGGCATCTTGATTCACTTTCTGTGA
AAGTGGAGTTGAAAGAAAGCAGCCTGACATTGACGCATGAGCAGCGTTGCCAGGTGTGCCACCAGCTGCGCCATCGGATT
AAATCGATGGTGGGGATCTCTACTGATGTGATGATCGTTAACTGTGGCAGTATCCCGCGTTCAGAAGGCAAGGCGTGTCG
GGTGTTTGATCTGCGCAATATTGTTGGTGCCTGA

Upstream 100 bases:

>100_bases
ACGGTCGTTACGCATTATGCACCATGTGCATCGGTGTCGGTCAGGGCATCGCCATGATTCTGGAGCGTGTTTGAGCATAT
CAACCTGCGAGTATCCTACA

Downstream 100 bases:

>100_bases
TGTGTCGCCTGGTCCTGGTGGGTGAACTGCCAGGGCCAGAAGTCGATACGACCTGTGCTATGATTCATAAATCACAACAA
TAACAACAGACTGAATCGAA

Product: phenylacetyl-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MITNTKLDPIETASVDELQALQTQRLKWTLKHAYENVPMYRRKFDAAGVHPDDFRELSDLRKFPCTTKQDLRDNYPFDTF
AVPMEQVVRIHASSGTTGKPTVVGYTQNDIDNWANIVARSLRAAGGTPKDKIHVAYGYGLFTGGLGAHYGAERLGATVIP
MSGGQTEKQAQLIRDFQPDMIMVTPSYCLNLIEELERQLGGDASGCSLRVGVFGAEPWTQAMRKEIERRLGITALDIYGL
SEVMGPGVAMECLETTDGPTIWEDHFYPEIVNPNDGTPLADGEHGELLFTTLTKEALPVIRYRTRDLTRLLPGTARTMRR
MDRISGRSDDMLIIRGVNVFPSQLEEEIVKFEHLSPHYQLEVNRRGHLDSLSVKVELKESSLTLTHEQRCQVCHQLRHRI
KSMVGISTDVMIVNCGSIPRSEGKACRVFDLRNIVGA

Sequences:

>Translated_437_residues
MITNTKLDPIETASVDELQALQTQRLKWTLKHAYENVPMYRRKFDAAGVHPDDFRELSDLRKFPCTTKQDLRDNYPFDTF
AVPMEQVVRIHASSGTTGKPTVVGYTQNDIDNWANIVARSLRAAGGTPKDKIHVAYGYGLFTGGLGAHYGAERLGATVIP
MSGGQTEKQAQLIRDFQPDMIMVTPSYCLNLIEELERQLGGDASGCSLRVGVFGAEPWTQAMRKEIERRLGITALDIYGL
SEVMGPGVAMECLETTDGPTIWEDHFYPEIVNPNDGTPLADGEHGELLFTTLTKEALPVIRYRTRDLTRLLPGTARTMRR
MDRISGRSDDMLIIRGVNVFPSQLEEEIVKFEHLSPHYQLEVNRRGHLDSLSVKVELKESSLTLTHEQRCQVCHQLRHRI
KSMVGISTDVMIVNCGSIPRSEGKACRVFDLRNIVGA
>Mature_437_residues
MITNTKLDPIETASVDELQALQTQRLKWTLKHAYENVPMYRRKFDAAGVHPDDFRELSDLRKFPCTTKQDLRDNYPFDTF
AVPMEQVVRIHASSGTTGKPTVVGYTQNDIDNWANIVARSLRAAGGTPKDKIHVAYGYGLFTGGLGAHYGAERLGATVIP
MSGGQTEKQAQLIRDFQPDMIMVTPSYCLNLIEELERQLGGDASGCSLRVGVFGAEPWTQAMRKEIERRLGITALDIYGL
SEVMGPGVAMECLETTDGPTIWEDHFYPEIVNPNDGTPLADGEHGELLFTTLTKEALPVIRYRTRDLTRLLPGTARTMRR
MDRISGRSDDMLIIRGVNVFPSQLEEEIVKFEHLSPHYQLEVNRRGHLDSLSVKVELKESSLTLTHEQRCQVCHQLRHRI
KSMVGISTDVMIVNCGSIPRSEGKACRVFDLRNIVGA

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=437, Percent_Identity=99.5423340961098, Blast_Score=906, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 48945; Mature: 48945

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITNTKLDPIETASVDELQALQTQRLKWTLKHAYENVPMYRRKFDAAGVHPDDFRELSDL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHH
RKFPCTTKQDLRDNYPFDTFAVPMEQVVRIHASSGTTGKPTVVGYTQNDIDNWANIVARS
HHCCCCCHHHHHCCCCCCHHHHCHHHHHEEECCCCCCCCCEEEEECHHHHHHHHHHHHHH
LRAAGGTPKDKIHVAYGYGLFTGGLGAHYGAERLGATVIPMSGGQTEKQAQLIRDFQPDM
HHHCCCCCCCEEEEEEECHHHCCCCCHHCCHHHHCCEEEECCCCCCHHHHHHHHHCCCCE
IMVTPSYCLNLIEELERQLGGDASGCSLRVGVFGAEPWTQAMRKEIERRLGITALDIYGL
EEECHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCEEEECCCH
SEVMGPGVAMECLETTDGPTIWEDHFYPEIVNPNDGTPLADGEHGELLFTTLTKEALPVI
HHHHCCCHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHH
RYRTRDLTRLLPGTARTMRRMDRISGRSDDMLIIRGVNVFPSQLEEEIVKFEHLSPHYQL
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEE
EVNRRGHLDSLSVKVELKESSLTLTHEQRCQVCHQLRHRIKSMVGISTDVMIVNCGSIPR
EECCCCCCCEEEEEEEEECCCEEECHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
SEGKACRVFDLRNIVGA
CCCCEEEEEEHHHHHCC
>Mature Secondary Structure
MITNTKLDPIETASVDELQALQTQRLKWTLKHAYENVPMYRRKFDAAGVHPDDFRELSDL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHH
RKFPCTTKQDLRDNYPFDTFAVPMEQVVRIHASSGTTGKPTVVGYTQNDIDNWANIVARS
HHCCCCCHHHHHCCCCCCHHHHCHHHHHEEECCCCCCCCCEEEEECHHHHHHHHHHHHHH
LRAAGGTPKDKIHVAYGYGLFTGGLGAHYGAERLGATVIPMSGGQTEKQAQLIRDFQPDM
HHHCCCCCCCEEEEEEECHHHCCCCCHHCCHHHHCCEEEECCCCCCHHHHHHHHHCCCCE
IMVTPSYCLNLIEELERQLGGDASGCSLRVGVFGAEPWTQAMRKEIERRLGITALDIYGL
EEECHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCEEEECCCH
SEVMGPGVAMECLETTDGPTIWEDHFYPEIVNPNDGTPLADGEHGELLFTTLTKEALPVI
HHHHCCCHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHH
RYRTRDLTRLLPGTARTMRRMDRISGRSDDMLIIRGVNVFPSQLEEEIVKFEHLSPHYQL
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEE
EVNRRGHLDSLSVKVELKESSLTLTHEQRCQVCHQLRHRIKSMVGISTDVMIVNCGSIPR
EECCCCCCCEEEEEEEEECCCEEECHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
SEGKACRVFDLRNIVGA
CCCCEEEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]