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The map label for this gene is yncC [H]

Identifier: 218548814

GI number: 218548814

Start: 1494095

End: 1494760

Strand: Direct

Name: yncC [H]

Synonym: EFER_1453

Alternate gene names: 218548814

Gene position: 1494095-1494760 (Clockwise)

Preceding gene: 218548813

Following gene: 218548816

Centisome position: 32.56

GC content: 43.69

Gene sequence:

>666_bases
ATGCCTGGAACGGAAAAAATACCGCATATCAGTTTAACTATGAAGGTTGAGAACGACCTGAAACATCAGCTTAGTATTGG
CGCACTAAAACCTGGCGCACGCCTGATTACTAAAAATCTGGCGGAGCAATTAGGTATGAGTATTACACCCGTGCGTGAAG
CATTATTACGTCTGGTTTCGGTGAATGCGCTCTCTGTCGCACCAGCGCAAGCATTTACAGTACCGGAAGTGGGGAAACGT
CAATTAGACGAAATCAATCGGATCCGCTACGAACTGGAATTAATGGCAGTTGCTCTGGCTGTTGAAAACCTCACCCCGCA
AGACCTGGCAGAACTTCAGGAATTGCTCGAGAAATTACAGCAGGCGCAAGAAAAGGGCGACATGGAAAAAATCATTAATG
CGAACAGACTATTTCGCTTAGCGGTTTATCATCGCTCAAATATGCCCATCCTGTGTGAAATGATTGAGCAACTGTGGATC
AGGATGGGGCCTGGTTTACATTATCTTTATGAAGCGATTAACCCAGCGGAATTACGTGAACGTATAGAAAGCTATCATGA
ACTACTCGCCGCGTTAAAAGTAAAAGACAAAGAGGGATGCAAACATTGTCTTGCTGAAATTATGCAACAAAACGTTGCTA
TGTTATACCAGCAATATAATCGTTAA

Upstream 100 bases:

>100_bases
AATAAAGGTGAGTGGATAATGATTATTCAGCTTCATACGCCAGGTAAACGACTTCTGCTGTGCTGGCAGAGTTGGAACGA
AAACACCTGAAGGAAATAAC

Downstream 100 bases:

>100_bases
ATTAAATGCCCGGCAAATACCGGGCATCAAGATAATCACTCAAATCGCCACGCAACATTCACGCCGATACCATAATTTCG
CCCGGGCGCAGGTTCGTAAT

Product: DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MPGTEKIPHISLTMKVENDLKHQLSIGALKPGARLITKNLAEQLGMSITPVREALLRLVSVNALSVAPAQAFTVPEVGKR
QLDEINRIRYELELMAVALAVENLTPQDLAELQELLEKLQQAQEKGDMEKIINANRLFRLAVYHRSNMPILCEMIEQLWI
RMGPGLHYLYEAINPAELRERIESYHELLAALKVKDKEGCKHCLAEIMQQNVAMLYQQYNR

Sequences:

>Translated_221_residues
MPGTEKIPHISLTMKVENDLKHQLSIGALKPGARLITKNLAEQLGMSITPVREALLRLVSVNALSVAPAQAFTVPEVGKR
QLDEINRIRYELELMAVALAVENLTPQDLAELQELLEKLQQAQEKGDMEKIINANRLFRLAVYHRSNMPILCEMIEQLWI
RMGPGLHYLYEAINPAELRERIESYHELLAALKVKDKEGCKHCLAEIMQQNVAMLYQQYNR
>Mature_220_residues
PGTEKIPHISLTMKVENDLKHQLSIGALKPGARLITKNLAEQLGMSITPVREALLRLVSVNALSVAPAQAFTVPEVGKRQ
LDEINRIRYELELMAVALAVENLTPQDLAELQELLEKLQQAQEKGDMEKIINANRLFRLAVYHRSNMPILCEMIEQLWIR
MGPGLHYLYEAINPAELRERIESYHELLAALKVKDKEGCKHCLAEIMQQNVAMLYQQYNR

Specific function: Important for biofilm formation. Represses expression of mcbA by binding to its promoter region, which prevents colanic acid overproduction and mucoidy [H]

COG id: COG1802

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081914, Length=221, Percent_Identity=92.3076923076923, Blast_Score=422, Evalue=1e-119,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 25191; Mature: 25060

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGTEKIPHISLTMKVENDLKHQLSIGALKPGARLITKNLAEQLGMSITPVREALLRLVS
CCCCCCCCCEEEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VNALSVAPAQAFTVPEVGKRQLDEINRIRYELELMAVALAVENLTPQDLAELQELLEKLQ
HHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
QAQEKGDMEKIINANRLFRLAVYHRSNMPILCEMIEQLWIRMGPGLHYLYEAINPAELRE
HHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHH
RIESYHELLAALKVKDKEGCKHCLAEIMQQNVAMLYQQYNR
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PGTEKIPHISLTMKVENDLKHQLSIGALKPGARLITKNLAEQLGMSITPVREALLRLVS
CCCCCCCCEEEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VNALSVAPAQAFTVPEVGKRQLDEINRIRYELELMAVALAVENLTPQDLAELQELLEKLQ
HHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
QAQEKGDMEKIINANRLFRLAVYHRSNMPILCEMIEQLWIRMGPGLHYLYEAINPAELRE
HHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHH
RIESYHELLAALKVKDKEGCKHCLAEIMQQNVAMLYQQYNR
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]