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The map label for this gene is astC [H]

Identifier: 218548683

GI number: 218548683

Start: 1355514

End: 1356734

Strand: Direct

Name: astC [H]

Synonym: EFER_1317

Alternate gene names: 218548683

Gene position: 1355514-1356734 (Clockwise)

Preceding gene: 218548674

Following gene: 218548684

Centisome position: 29.54

GC content: 55.36

Gene sequence:

>1221_bases
ATGTCTCAGCCAATTACGCGTGAAAACTTTGATGAATGGATGTTACCTGTTTACGCTCCGGCACCATTTATTCCGGTACG
TGGCGAAGGTTCGCGCTTGTGGGATCAGCAGGGGAAAGAGTATATCGACTTCGCGGGTGGCATTGCGGTGAACGCACTGG
GCCATGCGCACCCGGAACTGCGTGAGGCGCTGAACGAACAGGCGAGTAAGTTCTGGCATACCGGTAATGGTTACACCAAC
GAGCCGGTACTGCGACTGGCGAAAAAATTGATCGACGCCACTTTTGCCGATCGCGTCTTCTTTTGTAACTCCGGCGCGGA
AGCCAACGAAGCGGCACTGAAACTGGCGCGTAAATTCGCCCACGACCGCTACGGTAGCCATAAGAGCGGCATTGTGGCGT
TTAAAAATGCGTTCCACGGGCGCACGTTGTTTACCGTTAGTGCGGGCGGGCAGCCTGCCTATTCGCAGGATTTTGCGCCA
CTGCCGCCGGATATCCGTCATGCGGCGTATAACGATCTCAATTCTGCCAGTGCGCTGATTGACGACTCTACCTGTGCGGT
GATTGTCGAGCCCATCCAGGGGGAAGGCGGTGTGGTGCCAGCCAGCAACGCGTTTTTACAGGGTCTGCGTGAATTGTGTG
ACCGCCACAATGCATTGCTGATTTTTGATGAAGTACAAACAGGCGTCGGGCGTACCGGGGAACTGTATGCCTATATGCAC
TACGGCGTGACGCCCGATCTGTTAACTACCGCAAAAGCACTGGGCGGCGGTTTCCCCGTTGGCGCTCTGTTGGCAACCGA
AGAATGCGCCAGCGTGATGACCGTGGGCACTCATGGCACCACTTATGGCGGTAATCCGCTGGCCTCGGCGGTGGCAGGCA
AAGTGCTGGATCTCATCAACACGCCAGAGATGCTTATTGGCGTTAAACAGCGTCACGACTGGTTTGTTGAGCGTCTTAAT
ACCATTAATCACCGCTATGGTTTGTTCAGTGAAGTTCGCGGCTTAGGTCTGCTGATTGGCTGTGTGCTGAATGCGGATTA
CGCCGGGCAAGCGAAACAAATTTCTCAGGAGGCGGCAAAAGCGGGCGTGATGGTGCTGATTGCTGGTGGCAATGTGGTGC
GTTTTGCGCCTGCGCTCAACGTCAGCGAAGAAGAGGTGACGACCGGGCTGGATCGTTTTGCTGTGGCCTGTGAACGCTTT
GTGAGCGGAGGTTCATCATGA

Upstream 100 bases:

>100_bases
TTTATCACTGGCTGGCACGAACCCTGCAATCTACATTTACAGCGCAAACATTACTTATTATTAACATATAAATAACTAAT
TATTTACTGTAGAGGTCGCT

Downstream 100 bases:

>100_bases
TGGTCATCCGTCCCGTTGAACGCACTGATGTCTCAGCGTTAATGCAGCTTGCCAGCAAAACGGGCGGCGGCCTGACGTCG
CTTCCCGCCAATGAAGCCAC

Product: bifunctional succinylornithine transaminase/acetylornithine transaminase

Products: NA

Alternate protein names: Succinylornithine aminotransferase [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSQPITRENFDEWMLPVYAPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPELREALNEQASKFWHTGNGYTN
EPVLRLAKKLIDATFADRVFFCNSGAEANEAALKLARKFAHDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQPAYSQDFAP
LPPDIRHAAYNDLNSASALIDDSTCAVIVEPIQGEGGVVPASNAFLQGLRELCDRHNALLIFDEVQTGVGRTGELYAYMH
YGVTPDLLTTAKALGGGFPVGALLATEECASVMTVGTHGTTYGGNPLASAVAGKVLDLINTPEMLIGVKQRHDWFVERLN
TINHRYGLFSEVRGLGLLIGCVLNADYAGQAKQISQEAAKAGVMVLIAGGNVVRFAPALNVSEEEVTTGLDRFAVACERF
VSGGSS

Sequences:

>Translated_406_residues
MSQPITRENFDEWMLPVYAPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPELREALNEQASKFWHTGNGYTN
EPVLRLAKKLIDATFADRVFFCNSGAEANEAALKLARKFAHDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQPAYSQDFAP
LPPDIRHAAYNDLNSASALIDDSTCAVIVEPIQGEGGVVPASNAFLQGLRELCDRHNALLIFDEVQTGVGRTGELYAYMH
YGVTPDLLTTAKALGGGFPVGALLATEECASVMTVGTHGTTYGGNPLASAVAGKVLDLINTPEMLIGVKQRHDWFVERLN
TINHRYGLFSEVRGLGLLIGCVLNADYAGQAKQISQEAAKAGVMVLIAGGNVVRFAPALNVSEEEVTTGLDRFAVACERF
VSGGSS
>Mature_405_residues
SQPITRENFDEWMLPVYAPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPELREALNEQASKFWHTGNGYTNE
PVLRLAKKLIDATFADRVFFCNSGAEANEAALKLARKFAHDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQPAYSQDFAPL
PPDIRHAAYNDLNSASALIDDSTCAVIVEPIQGEGGVVPASNAFLQGLRELCDRHNALLIFDEVQTGVGRTGELYAYMHY
GVTPDLLTTAKALGGGFPVGALLATEECASVMTVGTHGTTYGGNPLASAVAGKVLDLINTPEMLIGVKQRHDWFVERLNT
INHRYGLFSEVRGLGLLIGCVLNADYAGQAKQISQEAAKAGVMVLIAGGNVVRFAPALNVSEEEVTTGLDRFAVACERFV
SGGSS

Specific function: Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=379, Percent_Identity=35.0923482849604, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI284507298, Length=293, Percent_Identity=35.8361774744027, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI13994255, Length=445, Percent_Identity=28.0898876404494, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI37574042, Length=422, Percent_Identity=27.9620853080569, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI226442705, Length=422, Percent_Identity=27.2511848341232, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI226442709, Length=387, Percent_Identity=28.1653746770026, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI24119277, Length=423, Percent_Identity=27.8959810874704, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI188536080, Length=427, Percent_Identity=23.8875878220141, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI38679950, Length=427, Percent_Identity=23.8875878220141, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI38679946, Length=427, Percent_Identity=23.8875878220141, Blast_Score=90, Evalue=4e-18,
Organism=Escherichia coli, GI1788044, Length=406, Percent_Identity=97.5369458128079, Blast_Score=817, Evalue=0.0,
Organism=Escherichia coli, GI1789759, Length=397, Percent_Identity=61.2090680100756, Blast_Score=515, Evalue=1e-147,
Organism=Escherichia coli, GI1789016, Length=398, Percent_Identity=33.9195979899498, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI145693181, Length=390, Percent_Identity=34.8717948717949, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1787560, Length=395, Percent_Identity=34.6835443037975, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1786349, Length=312, Percent_Identity=33.3333333333333, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1786991, Length=296, Percent_Identity=32.4324324324324, Blast_Score=127, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI25144271, Length=379, Percent_Identity=36.4116094986807, Blast_Score=238, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI32564660, Length=435, Percent_Identity=29.8850574712644, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI25144274, Length=275, Percent_Identity=35.2727272727273, Blast_Score=172, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=440, Percent_Identity=28.6363636363636, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71981843, Length=165, Percent_Identity=35.1515151515151, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17541228, Length=308, Percent_Identity=26.6233766233766, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324432, Length=394, Percent_Identity=41.1167512690355, Blast_Score=292, Evalue=8e-80,
Organism=Saccharomyces cerevisiae, GI6323470, Length=399, Percent_Identity=34.3358395989975, Blast_Score=214, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6324386, Length=325, Percent_Identity=29.2307692307692, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6321456, Length=366, Percent_Identity=26.5027322404372, Blast_Score=93, Evalue=8e-20,
Organism=Drosophila melanogaster, GI21357415, Length=379, Percent_Identity=35.6200527704486, Blast_Score=228, Evalue=4e-60,
Organism=Drosophila melanogaster, GI28574759, Length=445, Percent_Identity=29.8876404494382, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI161085790, Length=445, Percent_Identity=30.1123595505618, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI21356575, Length=366, Percent_Identity=29.5081967213115, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI281366494, Length=424, Percent_Identity=24.0566037735849, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24667139, Length=424, Percent_Identity=24.0566037735849, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24667143, Length=424, Percent_Identity=24.0566037735849, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.81 [H]

Molecular weight: Translated: 43557; Mature: 43425

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPITRENFDEWMLPVYAPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPEL
CCCCCCCCCHHHHCCEEECCCCCEEECCCCCHHHHHCCCHHHHHCCCHHHHHHCCCCHHH
REALNEQASKFWHTGNGYTNEPVLRLAKKLIDATFADRVFFCNSGAEANEAALKLARKFA
HHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHH
HDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQPAYSQDFAPLPPDIRHAAYNDLNSASALI
HHHCCCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHEE
DDSTCAVIVEPIQGEGGVVPASNAFLQGLRELCDRHNALLIFDEVQTGVGRTGELYAYMH
CCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECHHCCCCCCCCEEEEEE
YGVTPDLLTTAKALGGGFPVGALLATEECASVMTVGTHGTTYGGNPLASAVAGKVLDLIN
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHC
TPEMLIGVKQRHDWFVERLNTINHRYGLFSEVRGLGLLIGCVLNADYAGQAKQISQEAAK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AGVMVLIAGGNVVRFAPALNVSEEEVTTGLDRFAVACERFVSGGSS
CCEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SQPITRENFDEWMLPVYAPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPEL
CCCCCCCCHHHHCCEEECCCCCEEECCCCCHHHHHCCCHHHHHCCCHHHHHHCCCCHHH
REALNEQASKFWHTGNGYTNEPVLRLAKKLIDATFADRVFFCNSGAEANEAALKLARKFA
HHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHH
HDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQPAYSQDFAPLPPDIRHAAYNDLNSASALI
HHHCCCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHEE
DDSTCAVIVEPIQGEGGVVPASNAFLQGLRELCDRHNALLIFDEVQTGVGRTGELYAYMH
CCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECHHCCCCCCCCEEEEEE
YGVTPDLLTTAKALGGGFPVGALLATEECASVMTVGTHGTTYGGNPLASAVAGKVLDLIN
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHC
TPEMLIGVKQRHDWFVERLNTINHRYGLFSEVRGLGLLIGCVLNADYAGQAKQISQEAAK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AGVMVLIAGGNVVRFAPALNVSEEEVTTGLDRFAVACERFVSGGSS
CCEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA