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The map label for this gene is msrB

Identifier: 218548660

GI number: 218548660

Start: 1333825

End: 1334238

Strand: Direct

Name: msrB

Synonym: EFER_1294

Alternate gene names: 218548660

Gene position: 1333825-1334238 (Clockwise)

Preceding gene: 218548657

Following gene: 218548661

Centisome position: 29.07

GC content: 46.14

Gene sequence:

>414_bases
ATGGCGAATAAACCTTCGGTGGACGATCTCAAAGAAAATTTGTCCGAAATGCAGTTCTACGTCACGCAGAAACATGGCAC
CGAGCCGCCATATACCGGGCGTTTGCTGCATAACAAACGCGACGGGGTATACCGTTGTCTTGTTTGCGACACGCCGCTGT
TCAACTCCCAAAGTAAATATGACTCCGGCTGCGGTTGGCCAAGTTTTTACGAACCTGTTAATGAAAATTCAATACGATAT
TTAACAGATTTATCTCACGGTATGGAGCGCATAGAGATTCGTTGTGGTCATTGTGACGCTCATTTAGGGCATGTTTTTCC
TGATGGTCCGCAGCCCACAGGTGAACGTTATTGCGTCAATTCGGCCTCACTAAGTTTTACTGACGAGAAAAGTGGCGACC
AAATTAAAGGTTGA

Upstream 100 bases:

>100_bases
GTTAGAAACAAGTTTAGAACAAAAGTTGACGCCTGGCTGTTAATGTTTTGTTAGAATTGGTCGCGTAATGTGAGCCTGAT
TAAAAGCGAGATGTTAGCAA

Downstream 100 bases:

>100_bases
TAAAACGATTCAGCAAATTATTCCATGGGAGCGCAACCAGCATGAATTTTGACGACATCATTAACAGTATGACCCCCGAG
GTATATCAACGCCTGTCTAC

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MANKPSVDDLKENLSEMQFYVTQKHGTEPPYTGRLLHNKRDGVYRCLVCDTPLFNSQSKYDSGCGWPSFYEPVNENSIRY
LTDLSHGMERIEIRCGHCDAHLGHVFPDGPQPTGERYCVNSASLSFTDEKSGDQIKG

Sequences:

>Translated_137_residues
MANKPSVDDLKENLSEMQFYVTQKHGTEPPYTGRLLHNKRDGVYRCLVCDTPLFNSQSKYDSGCGWPSFYEPVNENSIRY
LTDLSHGMERIEIRCGHCDAHLGHVFPDGPQPTGERYCVNSASLSFTDEKSGDQIKG
>Mature_136_residues
ANKPSVDDLKENLSEMQFYVTQKHGTEPPYTGRLLHNKRDGVYRCLVCDTPLFNSQSKYDSGCGWPSFYEPVNENSIRYL
TDLSHGMERIEIRCGHCDAHLGHVFPDGPQPTGERYCVNSASLSFTDEKSGDQIKG

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family

Homologues:

Organism=Homo sapiens, GI301336164, Length=132, Percent_Identity=50, Blast_Score=156, Evalue=5e-39,
Organism=Homo sapiens, GI301336162, Length=132, Percent_Identity=50, Blast_Score=156, Evalue=5e-39,
Organism=Homo sapiens, GI73089054, Length=132, Percent_Identity=50, Blast_Score=156, Evalue=5e-39,
Organism=Homo sapiens, GI37620216, Length=132, Percent_Identity=50, Blast_Score=156, Evalue=5e-39,
Organism=Homo sapiens, GI117606353, Length=130, Percent_Identity=47.6923076923077, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI1788077, Length=137, Percent_Identity=82.4817518248175, Blast_Score=251, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17553450, Length=120, Percent_Identity=48.3333333333333, Blast_Score=120, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI115532676, Length=120, Percent_Identity=48.3333333333333, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6319816, Length=130, Percent_Identity=43.8461538461538, Blast_Score=106, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24645799, Length=122, Percent_Identity=46.7213114754098, Blast_Score=128, Evalue=9e-31,
Organism=Drosophila melanogaster, GI45553335, Length=122, Percent_Identity=46.7213114754098, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21356369, Length=122, Percent_Identity=46.7213114754098, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI221378664, Length=121, Percent_Identity=47.1074380165289, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI221378662, Length=128, Percent_Identity=44.53125, Blast_Score=124, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24645801, Length=133, Percent_Identity=42.8571428571429, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24645804, Length=133, Percent_Identity=44.3609022556391, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSRB_ESCF3 (B7LQ21)

Other databases:

- EMBL:   CU928158
- RefSeq:   YP_002382451.1
- EnsemblBacteria:   EBESCT00000125463
- GeneID:   7120173
- GenomeReviews:   CU928158_GR
- KEGG:   efe:EFER_1294
- GeneTree:   EBGT00050000011436
- HOGENOM:   HBG715255
- ProtClustDB:   PRK00222
- BioCyc:   EFER585054:EFER_1294-MONOMER
- HAMAP:   MF_01400
- InterPro:   IPR002579
- InterPro:   IPR011057
- Gene3D:   G3DSA:2.170.150.20
- TIGRFAMs:   TIGR00357

Pfam domain/function: PF01641 SelR; SSF51316 Mss4_like

EC number: =1.8.4.12

Molecular weight: Translated: 15463; Mature: 15332

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: ACT_SITE 118-118

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANKPSVDDLKENLSEMQFYVTQKHGTEPPYTGRLLHNKRDGVYRCLVCDTPLFNSQSKY
CCCCCCHHHHHHHHHHHHEEHCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCC
DSGCGWPSFYEPVNENSIRYLTDLSHGMERIEIRCGHCDAHLGHVFPDGPQPTGERYCVN
CCCCCCCHHCCCCCCCCEEEHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEC
SASLSFTDEKSGDQIKG
CCCEEECCCCCCCCCCC
>Mature Secondary Structure 
ANKPSVDDLKENLSEMQFYVTQKHGTEPPYTGRLLHNKRDGVYRCLVCDTPLFNSQSKY
CCCCCHHHHHHHHHHHHEEHCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCC
DSGCGWPSFYEPVNENSIRYLTDLSHGMERIEIRCGHCDAHLGHVFPDGPQPTGERYCVN
CCCCCCCHHCCCCCCCCEEEHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEC
SASLSFTDEKSGDQIKG
CCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA