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The map label for this gene is prc [H]

Identifier: 218548610

GI number: 218548610

Start: 1283522

End: 1285570

Strand: Direct

Name: prc [H]

Synonym: EFER_1244

Alternate gene names: 218548610

Gene position: 1283522-1285570 (Clockwise)

Preceding gene: 218548609

Following gene: 218548611

Centisome position: 27.97

GC content: 47.49

Gene sequence:

>2049_bases
ATGAACAGTTTTTTTAGGCTTACCGCGTTTGCTGGCCTGCTTGCAATAGCAGGCCAGACCTTCGCTGTAGATGATATTAC
ACGTGTTGAGCAAATTCCTGTTTTGAAGGAAGAAACTCAACACGCGACAGTAAGTGAGCGCGTGACTTCTCGTTTTACGC
GTTCGCATTATCGTCAGTTTGACCTCGATCAGGCGTTTTCTGCGAAAATATTCGATCGTTATCTGAATCTGCTTGATTAC
AGCCACAATGTGTTGCTGGCAAGTGACGTAGAAGCCTTCGCTAAAAAGAAAAATCAGCTTGGTGATGAATTACGTACGGG
CAAACTGGACGTCTTTTATGATCTCTATAATCTGGCACAAAAGCGCCGATTTGAGCGTTATCAGTACGCATTGAAAGTAC
TGGAACGCCCGATGGATTTCACGGGTAACGACACCTATAACCTTGACCGCAGCAAAGCTCCGTGGCCGAAAGACGAAGCG
GAAATGAATGCGTTGTGGGATGGCAAGGTGAAATTTGACGAATTAAGCCTGAAATTGACCGGTAAAACCGATCAGGAAAT
TCGTGACACCCTGACGCGTCGTTATAAATTTGCTATTCGTCGACTGGCACAAACCAACAGTGAAGATGTCTTCTCGCTGG
CGATGACCGCATTTGCACGTGAAATCGATCCTCATACCAATTATCTCTCTCCACGTAATACCGAACAGTTCAATACTGAA
ATGAGCCTGTCGCTGGAAGGTATTGGCGCAGTATTGCAGATGGATGATGACTACACCGTTATCAACTCCATGGTTGCCGG
TGGTCCGGCAGCGAAGAGCAAAGCGATAAGTGTGGGCGATCGTATTGTTGGTGTTGGGCAAACGGGTAAACCGATGGTCG
ATGTTATCGGTTGGCGTCTGGATGATGTCGTTGCCTTAATTAAAGGCCCTAAGGGCAGTAAGGTACGACTTGAGATCCTG
CCAGCAGGTAAGGGCACTAAAACTAAAACGATTACCCTGACGCGCGAACGTATTCGCCTGGAAGATCGCGCCGTTAAGAT
GTCGGTGAAAACCGTCGGTAAAGAAAAAGTTGGTGTGCTGGATATCCCTGGTTTCTACGTGGGCTTAACCGATGACGTTA
AAGTGCAGTTGCAGAAACTGGAAAAACAGAACGTCAGCAGTGTGATTATCGATCTGCGCAGTAACGGCGGTGGTGCGTTG
ACCGAGGCAGTTTCGCTTTCCGGTTTGTTTATCCCATCTGGCCCGGTGGTGCAGGTGCGTGATAACAACGGCAAGGTACG
TGAAGATAGCGACAACGATGGTGTGGTCTATTACAAAGGTCCGCTTGTTGTCCTTGTTGATCGTTTTAGTGCCTCTGCGT
CAGAGATCTTCGCTGCGGCGATGCAGGATTACGGCCGGGCATTGGTGGTTGGCGAACCGACCTTTGGTAAAGGTACCGTA
CAGCAGTACCGTTCTTTGAATCGTATTTACGATCAAATGTTGCGTCCTGAATGGCCTGCATTAGGTTCAGTACAGTATAC
AATCCAGAAATTTTATCGTGTTAACGGTGGCAGTACACAGCGTAAAGGTGTAACGCCAGACATCATCATGCCTACGGGCA
ATGAAGAGACGGAAACCGGCGAAAAATTCGAAGACAATGCATTACCGTGGGACAGTATTGACGCCGCAACTTACGTGAAA
TCAGGTGATCTGAAATCGTTTGGGCCGGAGCTGCTTAAAGAGCATAACGCTCGTATCGCTAATGATCCTGAATTCCAGTA
CATCATGAAGGATATTGCCCGTTTCAAAGCGATGAAGGAGAAGCGTAGTATTGCCTCGCTCAATTTTGCACAACGCGAAA
AAGAGAATAACGAAGATGATGCTTTGCGTCTGCAGCGCCTCAATGATCGGTTTAAACGTGAAGGTAAACCACAGTTGAAG
AAACTGGATGATCTGCCGAAAGATTATCAGGAGCCAGATCCGTATCTTGATGAAACGGTAAAAATAGCGCTCGACCTGGC
GCATCTTGAAAAAGAGAAGCCAGCGGAAAACCCCGCGTCTACTAAGTAA

Upstream 100 bases:

>100_bases
GAAATCACCAAAGACGGCGTCCGGGTACAGCTGAATTCGGGTATGTCTTTGATTGTGCGCGCAGAACACCTGGTGTTCTG
AAACGGAGGCCGGGCCTGGC

Downstream 100 bases:

>100_bases
TGTCAAACAGGCACAAGATAATGTGCCTGTTTTTTTTCACACGTCAGCCAAATGCTACAAAATGTAAAGTTGTGTCTTTC
TACTGACTTACACAGCGTTC

Product: carboxy-terminal protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]

Number of amino acids: Translated: 682; Mature: 682

Protein sequence:

>682_residues
MNSFFRLTAFAGLLAIAGQTFAVDDITRVEQIPVLKEETQHATVSERVTSRFTRSHYRQFDLDQAFSAKIFDRYLNLLDY
SHNVLLASDVEAFAKKKNQLGDELRTGKLDVFYDLYNLAQKRRFERYQYALKVLERPMDFTGNDTYNLDRSKAPWPKDEA
EMNALWDGKVKFDELSLKLTGKTDQEIRDTLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPRNTEQFNTE
MSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDRIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEIL
PAGKGTKTKTITLTRERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDLRSNGGGAL
TEAVSLSGLFIPSGPVVQVRDNNGKVREDSDNDGVVYYKGPLVVLVDRFSASASEIFAAAMQDYGRALVVGEPTFGKGTV
QQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAATYVK
SGDLKSFGPELLKEHNARIANDPEFQYIMKDIARFKAMKEKRSIASLNFAQREKENNEDDALRLQRLNDRFKREGKPQLK
KLDDLPKDYQEPDPYLDETVKIALDLAHLEKEKPAENPASTK

Sequences:

>Translated_682_residues
MNSFFRLTAFAGLLAIAGQTFAVDDITRVEQIPVLKEETQHATVSERVTSRFTRSHYRQFDLDQAFSAKIFDRYLNLLDY
SHNVLLASDVEAFAKKKNQLGDELRTGKLDVFYDLYNLAQKRRFERYQYALKVLERPMDFTGNDTYNLDRSKAPWPKDEA
EMNALWDGKVKFDELSLKLTGKTDQEIRDTLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPRNTEQFNTE
MSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDRIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEIL
PAGKGTKTKTITLTRERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDLRSNGGGAL
TEAVSLSGLFIPSGPVVQVRDNNGKVREDSDNDGVVYYKGPLVVLVDRFSASASEIFAAAMQDYGRALVVGEPTFGKGTV
QQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAATYVK
SGDLKSFGPELLKEHNARIANDPEFQYIMKDIARFKAMKEKRSIASLNFAQREKENNEDDALRLQRLNDRFKREGKPQLK
KLDDLPKDYQEPDPYLDETVKIALDLAHLEKEKPAENPASTK
>Mature_682_residues
MNSFFRLTAFAGLLAIAGQTFAVDDITRVEQIPVLKEETQHATVSERVTSRFTRSHYRQFDLDQAFSAKIFDRYLNLLDY
SHNVLLASDVEAFAKKKNQLGDELRTGKLDVFYDLYNLAQKRRFERYQYALKVLERPMDFTGNDTYNLDRSKAPWPKDEA
EMNALWDGKVKFDELSLKLTGKTDQEIRDTLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPRNTEQFNTE
MSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDRIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEIL
PAGKGTKTKTITLTRERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDLRSNGGGAL
TEAVSLSGLFIPSGPVVQVRDNNGKVREDSDNDGVVYYKGPLVVLVDRFSASASEIFAAAMQDYGRALVVGEPTFGKGTV
QQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAATYVK
SGDLKSFGPELLKEHNARIANDPEFQYIMKDIARFKAMKEKRSIASLNFAQREKENNEDDALRLQRLNDRFKREGKPQLK
KLDDLPKDYQEPDPYLDETVKIALDLAHLEKEKPAENPASTK

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=682, Percent_Identity=93.2551319648094, Blast_Score=1311, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 76788; Mature: 76788

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSFFRLTAFAGLLAIAGQTFAVDDITRVEQIPVLKEETQHATVSERVTSRFTRSHYRQF
CCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
DLDQAFSAKIFDRYLNLLDYSHNVLLASDVEAFAKKKNQLGDELRTGKLDVFYDLYNLAQ
CCHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KRRFERYQYALKVLERPMDFTGNDTYNLDRSKAPWPKDEAEMNALWDGKVKFDELSLKLT
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCEEEEEEEEEEE
GKTDQEIRDTLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPRNTEQFNTE
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCE
MSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDRIVGVGQTGKPMVDVIGWRL
EEEEECCCCEEEEECCCHHHHHHHHCCCCCCCCCEEECCCEEEECCCCCCCHHHHHCCCH
DDVVALIKGPKGSKVRLEILPAGKGTKTKTITLTRERIRLEDRAVKMSVKTVGKEKVGVL
HHHHHHHCCCCCCEEEEEEEECCCCCCEEEEEEEHHHHHHHHHHHEEHHHHCCCCCCCEE
DIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDLRSNGGGALTEAVSLSGLFIPSGPVVQVR
ECCCEEEECCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCEEEECCCCEEEEE
DNNGKVREDSDNDGVVYYKGPLVVLVDRFSASASEIFAAAMQDYGRALVVGEPTFGKGTV
CCCCCEECCCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCCHHH
QQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRVNGGSTQRKGVTPDIIMPTGNEETETG
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCC
EKFEDNALPWDSIDAATYVKSGDLKSFGPELLKEHNARIANDPEFQYIMKDIARFKAMKE
CCCCCCCCCCCCCCHHHEEECCCCHHCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
KRSIASLNFAQREKENNEDDALRLQRLNDRFKREGKPQLKKLDDLPKDYQEPDPYLDETV
HHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHCCCCCCHHHHH
KIALDLAHLEKEKPAENPASTK
HHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNSFFRLTAFAGLLAIAGQTFAVDDITRVEQIPVLKEETQHATVSERVTSRFTRSHYRQF
CCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
DLDQAFSAKIFDRYLNLLDYSHNVLLASDVEAFAKKKNQLGDELRTGKLDVFYDLYNLAQ
CCHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KRRFERYQYALKVLERPMDFTGNDTYNLDRSKAPWPKDEAEMNALWDGKVKFDELSLKLT
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCEEEEEEEEEEE
GKTDQEIRDTLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPRNTEQFNTE
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCE
MSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDRIVGVGQTGKPMVDVIGWRL
EEEEECCCCEEEEECCCHHHHHHHHCCCCCCCCCEEECCCEEEECCCCCCCHHHHHCCCH
DDVVALIKGPKGSKVRLEILPAGKGTKTKTITLTRERIRLEDRAVKMSVKTVGKEKVGVL
HHHHHHHCCCCCCEEEEEEEECCCCCCEEEEEEEHHHHHHHHHHHEEHHHHCCCCCCCEE
DIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDLRSNGGGALTEAVSLSGLFIPSGPVVQVR
ECCCEEEECCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCEEEECCCCEEEEE
DNNGKVREDSDNDGVVYYKGPLVVLVDRFSASASEIFAAAMQDYGRALVVGEPTFGKGTV
CCCCCEECCCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCCHHH
QQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRVNGGSTQRKGVTPDIIMPTGNEETETG
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCC
EKFEDNALPWDSIDAATYVKSGDLKSFGPELLKEHNARIANDPEFQYIMKDIARFKAMKE
CCCCCCCCCCCCCCHHHEEECCCCHHCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
KRSIASLNFAQREKENNEDDALRLQRLNDRFKREGKPQLKKLDDLPKDYQEPDPYLDETV
HHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHCCCCCCHHHHH
KIALDLAHLEKEKPAENPASTK
HHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]