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The map label for this gene is argS [H]

Identifier: 218548565

GI number: 218548565

Start: 1240810

End: 1242543

Strand: Reverse

Name: argS [H]

Synonym: EFER_1197

Alternate gene names: 218548565

Gene position: 1242543-1240810 (Counterclockwise)

Preceding gene: 218548568

Following gene: 218548558

Centisome position: 27.08

GC content: 51.15

Gene sequence:

>1734_bases
GTGAATATTCAGGCTCTTCTCTCAGAAAAAGTCCGTCAGGCCATGATTGCGGCAGGCGCGCCTGCGGATTGCGAACCGCA
GGTTCGTCAGTCAGCAAAAGTTCAGTTCGGCGACTATCAGGCTAACGGCATGATGGCAGTTGCTAAAAAACTGGGTATGG
CACCGCGACAATTAGCAGAGCAGGTGCTTACTCATCTGGATCTTAACGGTATCGCCAGCAAAGTTGAGATCGCGGGTCCT
GGCTTTATTAACATTTTCCTTGATCCGACATTCCTCGCTGAAAACGTTCAGCAGGCGCTAAAATCTGATCGTCTTGGTGT
CGCAACGCCCGAAAAACAGACCATTGTGGTTGACTACTCCGCACCAAACGTGGCGAAAGAGATGCACGTCGGTCATCTGC
GTTCCACCATCATTGGTGACGCGGCAGTGCGTACCCTGGAGTTCCTCGGTCACAAAGTGATTCGTGCTAACCACGTCGGT
GACTGGGGTACTCAGTTCGGTATGCTGATTGCCTGGCTGGAAAAACAGCAGCAGGAAAATGCCGGTGAAATGGCCCTGGC
TGACCTTGAAGGTTTCTACCGTGACGCGAAAAAACATTACGACGAAGATGAAGAGTTCGCCGAGCGCGCACGTAACTATG
TGGTAAAACTGCAAAGTGGTGATGAGTATTTTCGTGAGATGTGGCGCAAACTGGTCGACATCACCATGACTCAGAACCAA
ATCACCTATGATCGTCTGAACGTGACGCTGACTCGTGATGACGTAATGGGCGAAAGCCTCTACAACCCGATGCTACCGGG
AATTGTGGCTGATCTGAAAGCCAAAGGTCTGGCAGTAGAAAGTGAAGGTGCAACTGTCGTATTCCTTGATGAGTTCAAAA
ACAAGGAAGGCGATCCGATGGGCGTTATCATTCAGAAGAAAGATGGCGGCTATCTCTACACCACCACCGATATTGCCTGC
GCGAAATATCGTTACGAGACGCTACATGCCGATCGCGTACTCTATTACATCGACTCCCGTCAGCACCAGCACCTGATGCA
GGCGTGGGCGATTGTTCGTAAAGCTGGCTATGTGCCGGAATCTGTGCCGCTGGAACATCATATGTTTGGCATGATGCTGG
GCAAAGATGGTAAACCGTTCAAAACCCGTGCTGGCGGTACAGTGAAACTGGCGGATCTGCTGGATGAAGCACTGGAGCGT
GCACGCCGTCTGGTGGCAGAGAAGAACCCGGATATGCCAGCTGACGAACTGGAAAAACTGGCCAATGCAGTCGGTATCGG
TGCGGTGAAATATGCTGATCTTTCCAAAAACCGTACTACTGACTATGTCTTCGACTGGGACAATATGTTGGCGTTCGAAG
GTAACACCGCGCCGTATATGCAATATGCATACACTCGTGTGCTTTCCGTTTTCCGCAAAGCAGAAATTGCTGAAGAAGAA
CTGGCAGCAGCTCCGGTGATTATCCGTGAAGACCGCGAAGCGCAACTGGCTGCGCGTCTGCTGCAGTTTGAAGAGACTCT
CACCGTGGTTGCCCGTGAAGGTACACCGCACGTGATGTGTGCTTATCTGTATGATCTGGCTGGTCTGTTCTCAAGTTTCT
ACGAACACTGCCCGATCCTCAGCGCAGAAAACGAAGAAGTACGTAACAGCCGTCTGAAGCTGGCATTGCTGACTGCTAAG
ACGCTGAAACTGGGTCTGGATACGCTGGGTATTGAAACAGTAGAACGCATGTAA

Upstream 100 bases:

>100_bases
TCCAGTGCTGACGGCAACGGGCATTTGCAGTATACTCGCGGCCTAATTTCTTAAACTGATGCGGGTGAACAGACTCGCTT
CATCAACGTAAGGTATTCCG

Downstream 100 bases:

>100_bases
ACGTGTTCTGCGTCAAAAAGCCGATGTCAGCAACATCGGCTTTTTGACAAAGTGTACTTTGTTTATGCCGGATGCGGCAT
TAATGCCTTGTCCGGTAAAT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGP
GFINIFLDPTFLAENVQQALKSDRLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVG
DWGTQFGMLIAWLEKQQQENAGEMALADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQ
ITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGDPMGVIIQKKDGGYLYTTTDIAC
AKYRYETLHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALER
ARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYVFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEIAEEE
LAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSSFYEHCPILSAENEEVRNSRLKLALLTAK
TLKLGLDTLGIETVERM

Sequences:

>Translated_577_residues
MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGP
GFINIFLDPTFLAENVQQALKSDRLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVG
DWGTQFGMLIAWLEKQQQENAGEMALADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQ
ITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGDPMGVIIQKKDGGYLYTTTDIAC
AKYRYETLHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALER
ARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYVFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEIAEEE
LAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSSFYEHCPILSAENEEVRNSRLKLALLTAK
TLKLGLDTLGIETVERM
>Mature_577_residues
MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGP
GFINIFLDPTFLAENVQQALKSDRLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVG
DWGTQFGMLIAWLEKQQQENAGEMALADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQ
ITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGDPMGVIIQKKDGGYLYTTTDIAC
AKYRYETLHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALER
ARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYVFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEIAEEE
LAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSSFYEHCPILSAENEEVRNSRLKLALLTAK
TLKLGLDTLGIETVERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=599, Percent_Identity=38.3973288814691, Blast_Score=390, Evalue=1e-108,
Organism=Homo sapiens, GI197100773, Length=540, Percent_Identity=29.2592592592593, Blast_Score=198, Evalue=1e-50,
Organism=Escherichia coli, GI1788184, Length=577, Percent_Identity=98.2668977469671, Blast_Score=1176, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985061, Length=600, Percent_Identity=37.3333333333333, Blast_Score=372, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI71985068, Length=564, Percent_Identity=37.9432624113475, Blast_Score=363, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17532153, Length=384, Percent_Identity=27.6041666666667, Blast_Score=147, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320548, Length=544, Percent_Identity=34.7426470588235, Blast_Score=260, Evalue=4e-70,
Organism=Saccharomyces cerevisiae, GI6321883, Length=538, Percent_Identity=28.996282527881, Blast_Score=214, Evalue=3e-56,
Organism=Drosophila melanogaster, GI18859963, Length=600, Percent_Identity=37.3333333333333, Blast_Score=389, Evalue=1e-108,
Organism=Drosophila melanogaster, GI28571570, Length=510, Percent_Identity=28.6274509803922, Blast_Score=166, Evalue=6e-41,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 64634; Mature: 64634

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAE
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCEEECCCCCCCHHHHHHHHCCCHHHHHH
QVLTHLDLNGIASKVEIAGPGFINIFLDPTFLAENVQQALKSDRLGVATPEKQTIVVDYS
HHHHHCCCCCCCCEEEECCCCEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEC
APNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVGDWGTQFGMLIAWLEKQQQEN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHCC
AGEMALADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQ
CCCEEHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEECCCHHHHHHHHHHHHHEEECCCE
ITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGDPM
EEEEEEEEEEECCHHHHHHHHCCCCCHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCE
GVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPE
EEEEEECCCCEEEEECCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCC
SVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNPDMPADELEKL
CCCHHHHHHHHHCCCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ANAVGIGAVKYADLSKNRTTDYVFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEIAEEE
HHHHCCCCEEEECCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
LAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSSFYEHCPIL
HHHCCEEEECCCHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCC
SAENEEVRNSRLKLALLTAKTLKLGLDTLGIETVERM
CCCCHHHHHCCEEEEEEEHHHHHHHHHHHCHHHHHCC
>Mature Secondary Structure
MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAE
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCEEECCCCCCCHHHHHHHHCCCHHHHHH
QVLTHLDLNGIASKVEIAGPGFINIFLDPTFLAENVQQALKSDRLGVATPEKQTIVVDYS
HHHHHCCCCCCCCEEEECCCCEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEC
APNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVGDWGTQFGMLIAWLEKQQQEN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHCC
AGEMALADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQ
CCCEEHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEECCCHHHHHHHHHHHHHEEECCCE
ITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGDPM
EEEEEEEEEEECCHHHHHHHHCCCCCHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCE
GVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPE
EEEEEECCCCEEEEECCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCC
SVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNPDMPADELEKL
CCCHHHHHHHHHCCCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ANAVGIGAVKYADLSKNRTTDYVFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEIAEEE
HHHHCCCCEEEECCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
LAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSSFYEHCPIL
HHHCCEEEECCCHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCC
SAENEEVRNSRLKLALLTAKTLKLGLDTLGIETVERM
CCCCHHHHHCCEEEEEEEHHHHHHHHHHHCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA