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The map label for this gene is kch [H]

Identifier: 218548552

GI number: 218548552

Start: 1222838

End: 1224100

Strand: Reverse

Name: kch [H]

Synonym: EFER_1184

Alternate gene names: 218548552

Gene position: 1224100-1222838 (Counterclockwise)

Preceding gene: 218548555

Following gene: 218548548

Centisome position: 26.68

GC content: 43.23

Gene sequence:

>1263_bases
TTGCAGAGGTTTTCAGTGAGTCACTTGGCTGTATTTAAAAGAGTAATTATAAAATTATGGCTGGCATGCAGGCATGATAT
AACCGCTCTGGCTGTACTTATTAACGGTTTACTTATTTTTAAAACCATTTATGGAATGTCTGTTAGCCTGTTGGATATTT
TCCATATCCACGCCTACACAGGATTAGATCTTTCACTGCTTGCTAACGCCCCACTGTTCATGCTTGGGGTGTTTCTGGTT
TTGAACTCCATTGGTTTGCTTTTTCGCGCCAAACTTGCCTGGGCCATAAGCCTGATACTGCTGTTGATTACACTAATCTA
CACACTGCATTTCTATCCTTATCTTAAATTCAGTATCGGTTTTTGCCTCTTTACGATGGTGATGCTGCTGTTACTGAGTA
AAGATTTTTCCCACAGCAGCGCCACTGCGGGCAGTATCTTTGCGTTTATCAGTTTCACCACCTTATTGTTTTACTCTACC
TATGGTTCGCTATATTTGGGAGAAGGCTTCAATCCCAAAATAGAAAGTCTGGTGACTGCATTCTATTTTTCAATAGAAAC
CATGACTACTGTCGGTTATGGCGATATTGTGCCGGTTTCAGAGACTGCCCGCTTGTTCACTGTATCGGTTATTATTTCGG
GCATTACGGTTTTCGCAACATCTATTACATCGATTTTTGGCCCGCTAATCCGCGGCGGCCTGAACAGACTGGTTAAAGGG
AAAAAACATACTATGAATCGCAAAGATCACTTTATTGTCTGCGGTCACTCTATTCTGGCGGTAAACACTATCTTGCAACT
CAACCAGCGTGGGCAAAAAGTTACCGTGATCACTAACCTGCCAGAAGATGAAGCTAATCTGCTGGATCAGCGGTTAGGTG
GCAATTTCGATATGATTTTAGGTGACAGTAATGACAGCGCGATTTTGAAAAAAGCCGGCATTGACGACTGCCGGGCGATT
CTGGCGCTCAGTGACAATGATGCCGATAACGCCTTTGTGGTGCTTTCAGCGAAAGATCTCAGCAAAGATGTCAAAACTGT
ATTGGCAGTAAGCGACAGCAAAAACCTGAACAAAGTGAAAAAAGTACAACCTGATATCATCCTGTCACCACAATTATTTG
GTAGCGAGATTTTAGCCCGTATCTTAAACGGCGAAGAGATCGACAATAATATGCTGGTATCGATGCTACTGAACTCCGGG
CATGGACTGTTTGGTGATAACGAGGCAGAGGAGAATGCGCCACAGCAATCAGCTGGTAAATAG

Upstream 100 bases:

>100_bases
AAATCTTTGATTCTTGAGGATAATCTCATCTAGTATTATCTGACAGGTTGAAAATCCGACTTGCTCTGGCGGGATAAAAC
CACCAGTTAATTGAGAAAAG

Downstream 100 bases:

>100_bases
CAAGTTAGCGGGGAGTATCTGTAGAGGGCGACGATGCCCTCTTTTTTTGCATTTACGTTGGAAATAATAAAGACAAAAAC
AAAAAAACCACCCGAAGGTG

Product: voltage-gated potassium channel

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MQRFSVSHLAVFKRVIIKLWLACRHDITALAVLINGLLIFKTIYGMSVSLLDIFHIHAYTGLDLSLLANAPLFMLGVFLV
LNSIGLLFRAKLAWAISLILLLITLIYTLHFYPYLKFSIGFCLFTMVMLLLLSKDFSHSSATAGSIFAFISFTTLLFYST
YGSLYLGEGFNPKIESLVTAFYFSIETMTTVGYGDIVPVSETARLFTVSVIISGITVFATSITSIFGPLIRGGLNRLVKG
KKHTMNRKDHFIVCGHSILAVNTILQLNQRGQKVTVITNLPEDEANLLDQRLGGNFDMILGDSNDSAILKKAGIDDCRAI
LALSDNDADNAFVVLSAKDLSKDVKTVLAVSDSKNLNKVKKVQPDIILSPQLFGSEILARILNGEEIDNNMLVSMLLNSG
HGLFGDNEAEENAPQQSAGK

Sequences:

>Translated_420_residues
MQRFSVSHLAVFKRVIIKLWLACRHDITALAVLINGLLIFKTIYGMSVSLLDIFHIHAYTGLDLSLLANAPLFMLGVFLV
LNSIGLLFRAKLAWAISLILLLITLIYTLHFYPYLKFSIGFCLFTMVMLLLLSKDFSHSSATAGSIFAFISFTTLLFYST
YGSLYLGEGFNPKIESLVTAFYFSIETMTTVGYGDIVPVSETARLFTVSVIISGITVFATSITSIFGPLIRGGLNRLVKG
KKHTMNRKDHFIVCGHSILAVNTILQLNQRGQKVTVITNLPEDEANLLDQRLGGNFDMILGDSNDSAILKKAGIDDCRAI
LALSDNDADNAFVVLSAKDLSKDVKTVLAVSDSKNLNKVKKVQPDIILSPQLFGSEILARILNGEEIDNNMLVSMLLNSG
HGLFGDNEAEENAPQQSAGK
>Mature_420_residues
MQRFSVSHLAVFKRVIIKLWLACRHDITALAVLINGLLIFKTIYGMSVSLLDIFHIHAYTGLDLSLLANAPLFMLGVFLV
LNSIGLLFRAKLAWAISLILLLITLIYTLHFYPYLKFSIGFCLFTMVMLLLLSKDFSHSSATAGSIFAFISFTTLLFYST
YGSLYLGEGFNPKIESLVTAFYFSIETMTTVGYGDIVPVSETARLFTVSVIISGITVFATSITSIFGPLIRGGLNRLVKG
KKHTMNRKDHFIVCGHSILAVNTILQLNQRGQKVTVITNLPEDEANLLDQRLGGNFDMILGDSNDSAILKKAGIDDCRAI
LALSDNDADNAFVVLSAKDLSKDVKTVLAVSDSKNLNKVKKVQPDIILSPQLFGSEILARILNGEEIDNNMLVSMLLNSG
HGLFGDNEAEENAPQQSAGK

Specific function: May play a role in the defense against osmotic shock [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787503, Length=417, Percent_Identity=81.294964028777, Blast_Score=666, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF07885 Ion_trans_2; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 46072; Mature: 46072

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRFSVSHLAVFKRVIIKLWLACRHDITALAVLINGLLIFKTIYGMSVSLLDIFHIHAYT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
GLDLSLLANAPLFMLGVFLVLNSIGLLFRAKLAWAISLILLLITLIYTLHFYPYLKFSIG
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FCLFTMVMLLLLSKDFSHSSATAGSIFAFISFTTLLFYSTYGSLYLGEGFNPKIESLVTA
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHH
FYFSIETMTTVGYGDIVPVSETARLFTVSVIISGITVFATSITSIFGPLIRGGLNRLVKG
HHHHHHHHEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KKHTMNRKDHFIVCGHSILAVNTILQLNQRGQKVTVITNLPEDEANLLDQRLGGNFDMIL
CHHCCCCCCCEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEE
GDSNDSAILKKAGIDDCRAILALSDNDADNAFVVLSAKDLSKDVKTVLAVSDSKNLNKVK
ECCCCCHHHHHCCCHHHHEEEEECCCCCCCEEEEEECHHHHHHHHHHHEECCCCCHHHHH
KVQPDIILSPQLFGSEILARILNGEEIDNNMLVSMLLNSGHGLFGDNEAEENAPQQSAGK
HCCCCEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQRFSVSHLAVFKRVIIKLWLACRHDITALAVLINGLLIFKTIYGMSVSLLDIFHIHAYT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
GLDLSLLANAPLFMLGVFLVLNSIGLLFRAKLAWAISLILLLITLIYTLHFYPYLKFSIG
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FCLFTMVMLLLLSKDFSHSSATAGSIFAFISFTTLLFYSTYGSLYLGEGFNPKIESLVTA
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHH
FYFSIETMTTVGYGDIVPVSETARLFTVSVIISGITVFATSITSIFGPLIRGGLNRLVKG
HHHHHHHHEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KKHTMNRKDHFIVCGHSILAVNTILQLNQRGQKVTVITNLPEDEANLLDQRLGGNFDMIL
CHHCCCCCCCEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEE
GDSNDSAILKKAGIDDCRAILALSDNDADNAFVVLSAKDLSKDVKTVLAVSDSKNLNKVK
ECCCCCHHHHHCCCHHHHEEEEECCCCCCCEEEEEECHHHHHHHHHHHEECCCCCHHHHH
KVQPDIILSPQLFGSEILARILNGEEIDNNMLVSMLLNSGHGLFGDNEAEENAPQQSAGK
HCCCCEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8170937; 9097039; 9278503 [H]