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The map label for this gene is yfbF

Identifier: 218548296

GI number: 218548296

Start: 931234

End: 932214

Strand: Reverse

Name: yfbF

Synonym: EFER_0915

Alternate gene names: 218548296

Gene position: 932214-931234 (Counterclockwise)

Preceding gene: 218548297

Following gene: 218548295

Centisome position: 20.32

GC content: 48.01

Gene sequence:

>981_bases
ATGTTTGAAATCCACCCTATTAAGAAAGTCTCGGTGGTTATTCCTGTTTATAACGAGCAGGAAAGCTTACCGGAATTGAT
TAATCGCACCACAGCGGCCTGCGAATCCCTGGGCAAAGAATATGAAATTTTATTAATAGACGATGGAAGTAGCGATGCTT
CTGCGCAAATGTTAGTAGAAGCATCACAAGCCCCGGACAGCCACATTGTGTCTATTTTGCTGAATCGTAATTACGGGCAA
CATTCAGCCATTATGGCGGGTTTTAGCTATGTGACCGGGGATTTGATCATTACTCTCGACGCCGATTTACAAAATCCTCC
AGAAGAGATCCCACGCCTGGTAGCCAAAGCGGATGAAGGCTATGACGTGGTAGGTACAGTACGTCAGAATCGCCAGGACA
GCTGGTTTCGCAAAACTGCCTCAAAGATGATCAATCGGCTCATCCAGCGCACCACCGGCAAAGCGATGGGCGACTACGGT
TGTATGCTGCGTGCCTATCGCCGTCATATTGTCGATGCGATGCTGCACTGCCATGAACGCAGCACCTTTATTCCGATTCT
GGCGAATATTTTTGCCCGCCAGGCAGTTGAGATCCCTGTGCATCACGCAGAGAGAGAGTTTGGTGAATCCAAATATAGCT
TTATGCGTTTGATTAACCTGATGTACGACCTGGTGACCTGCCTTACGACCACACCACTACGCATGCTCAGTCTTCTCGGC
AGCATTATAGCTACCTCAGGATTTAGCCTCGCAATACTGTTAGTTGTATTGCGTCTGGCGTTTGGCTCCCAGTGGTCCGG
TGAAGGTGTCTTTATGTTGTTTGCCGTGCTCTTCACCTTTATTGGTGCCCAGTTTATTGGCATGGGATTACTTGGCGAGT
ATATCGGCAGGATCTACAACGATGTCCGTGCCCGTCCACGCTACTTCGTTCAAAAAGTAATCCGTCCGGCAAGTTCTATA
GATATTGAGGAAAACCACTAA

Upstream 100 bases:

>100_bases
TAGCGAACGCATCTGCTCGTTGCCACTTTTCCCGGATATGACGAACGCAGATGCTGAACGCGTCATTACTGCCCTTCACC
AACTCGCAGGACAATAAACG

Downstream 100 bases:

>100_bases
TGAAAGCCGTTGTTTTTGCCTATCACGATATGGGCTGCCTTGGCGTACAAGCATTGCTGGACGCAGGTTATGAGATTAGC
GCTATTTTTACTCATGCGGA

Product: undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase

Products: NA

Alternate protein names: Undecaprenyl-phosphate Ara4FN transferase; Ara4FN transferase

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MFEIHPIKKVSVVIPVYNEQESLPELINRTTAACESLGKEYEILLIDDGSSDASAQMLVEASQAPDSHIVSILLNRNYGQ
HSAIMAGFSYVTGDLIITLDADLQNPPEEIPRLVAKADEGYDVVGTVRQNRQDSWFRKTASKMINRLIQRTTGKAMGDYG
CMLRAYRRHIVDAMLHCHERSTFIPILANIFARQAVEIPVHHAEREFGESKYSFMRLINLMYDLVTCLTTTPLRMLSLLG
SIIATSGFSLAILLVVLRLAFGSQWSGEGVFMLFAVLFTFIGAQFIGMGLLGEYIGRIYNDVRARPRYFVQKVIRPASSI
DIEENH

Sequences:

>Translated_326_residues
MFEIHPIKKVSVVIPVYNEQESLPELINRTTAACESLGKEYEILLIDDGSSDASAQMLVEASQAPDSHIVSILLNRNYGQ
HSAIMAGFSYVTGDLIITLDADLQNPPEEIPRLVAKADEGYDVVGTVRQNRQDSWFRKTASKMINRLIQRTTGKAMGDYG
CMLRAYRRHIVDAMLHCHERSTFIPILANIFARQAVEIPVHHAEREFGESKYSFMRLINLMYDLVTCLTTTPLRMLSLLG
SIIATSGFSLAILLVVLRLAFGSQWSGEGVFMLFAVLFTFIGAQFIGMGLLGEYIGRIYNDVRARPRYFVQKVIRPASSI
DIEENH
>Mature_326_residues
MFEIHPIKKVSVVIPVYNEQESLPELINRTTAACESLGKEYEILLIDDGSSDASAQMLVEASQAPDSHIVSILLNRNYGQ
HSAIMAGFSYVTGDLIITLDADLQNPPEEIPRLVAKADEGYDVVGTVRQNRQDSWFRKTASKMINRLIQRTTGKAMGDYG
CMLRAYRRHIVDAMLHCHERSTFIPILANIFARQAVEIPVHHAEREFGESKYSFMRLINLMYDLVTCLTTTPLRMLSLLG
SIIATSGFSLAILLVVLRLAFGSQWSGEGVFMLFAVLFTFIGAQFIGMGLLGEYIGRIYNDVRARPRYFVQKVIRPASSI
DIEENH

Specific function: Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family

Homologues:

Organism=Homo sapiens, GI4503363, Length=237, Percent_Identity=29.1139240506329, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1788588, Length=319, Percent_Identity=92.7899686520376, Blast_Score=621, Evalue=1e-179,
Organism=Escherichia coli, GI1788692, Length=315, Percent_Identity=32.3809523809524, Blast_Score=167, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI71999402, Length=226, Percent_Identity=26.9911504424779, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6325441, Length=228, Percent_Identity=25, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24585265, Length=235, Percent_Identity=27.6595744680851, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARNC_ESCF3 (B7LM77)

Other databases:

- EMBL:   CU928158
- RefSeq:   YP_002382087.1
- EnsemblBacteria:   EBESCT00000123693
- GeneID:   7123595
- GenomeReviews:   CU928158_GR
- KEGG:   efe:EFER_0915
- GeneTree:   EBGT00050000010589
- HOGENOM:   HBG752660
- ProtClustDB:   PRK10714
- BioCyc:   EFER585054:EFER_0915-MONOMER
- HAMAP:   MF_01164
- InterPro:   IPR022857
- InterPro:   IPR001173

Pfam domain/function: PF00535 Glycos_transf_2

EC number: =2.7.8.30

Molecular weight: Translated: 36597; Mature: 36597

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x26f2564c)-; HASH(0x40580460)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEIHPIKKVSVVIPVYNEQESLPELINRTTAACESLGKEYEILLIDDGSSDASAQMLVE
CCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHH
ASQAPDSHIVSILLNRNYGQHSAIMAGFSYVTGDLIITLDADLQNPPEEIPRLVAKADEG
HHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCCCC
YDVVGTVRQNRQDSWFRKTASKMINRLIQRTTGKAMGDYGCMLRAYRRHIVDAMLHCHER
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
STFIPILANIFARQAVEIPVHHAEREFGESKYSFMRLINLMYDLVTCLTTTPLRMLSLLG
CHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIIATSGFSLAILLVVLRLAFGSQWSGEGVFMLFAVLFTFIGAQFIGMGLLGEYIGRIYN
HHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVRARPRYFVQKVIRPASSIDIEENH
HHHCCHHHHHHHHHCCHHCCCCCCCH
>Mature Secondary Structure
MFEIHPIKKVSVVIPVYNEQESLPELINRTTAACESLGKEYEILLIDDGSSDASAQMLVE
CCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHH
ASQAPDSHIVSILLNRNYGQHSAIMAGFSYVTGDLIITLDADLQNPPEEIPRLVAKADEG
HHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCCCC
YDVVGTVRQNRQDSWFRKTASKMINRLIQRTTGKAMGDYGCMLRAYRRHIVDAMLHCHER
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
STFIPILANIFARQAVEIPVHHAEREFGESKYSFMRLINLMYDLVTCLTTTPLRMLSLLG
CHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIIATSGFSLAILLVVLRLAFGSQWSGEGVFMLFAVLFTFIGAQFIGMGLLGEYIGRIYN
HHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVRARPRYFVQKVIRPASSIDIEENH
HHHCCHHHHHHHHHCCHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA