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The map label for this gene is xseA [H]

Identifier: 218548057

GI number: 218548057

Start: 678889

End: 680256

Strand: Reverse

Name: xseA [H]

Synonym: EFER_0666

Alternate gene names: 218548057

Gene position: 680256-678889 (Counterclockwise)

Preceding gene: 218548060

Following gene: 218548042

Centisome position: 14.82

GC content: 54.61

Gene sequence:

>1368_bases
ATGTTACCTTCTCAATCCCCTGCAATTTTTACCGTTAGCCGCCTGAATCAAACGGTTCGTCTGCTGCTTGAGCATGAGAT
GGGGCAGGTGTGGATCAGTGGCGAAATCTCTAATTTCACACAACCGGCTTCCGGTCACTGGTACTTTACGCTTAAAGACG
ATAACGCCCAGGTGCGCTGCGCGATGTTCCGCAACAGCAATCGCCGGGTGACCTTTCGCCCGCAGCATGGGCAACAGGTT
TTAGTTCGTGCCAACATTACACTGTATGAACCGCGCGGCGATTATCAGATTATCGTCGAAAGTATGCAGCCCGCTGGTGA
AGGTTTGCTGCAACAGAAGTACGAACAGCTTAAAGCGAAGTTGCAGGCTGAAGGTTTGTTCGATCAGCAACTTAAAAAAA
CACTCCCCTCCCCTGCGCACTGCGTGGGTGTCATCACCTCAAAAACGGGCGCCGCACTGCACGATATTTTGCACGTGTTA
AAGCGTCGCGATCCTTCCCTGCCAGTGATTATTTACCCCACAGCCGTTCAGGGCGATGACGCACCAGGGCAAATCGTTCG
TGCCATTGAGCTGGCGAATCTTCGCAACGAATGTGACGTATTGATCGTCGGGCGTGGCGGTGGTTCGCTGGAAGATTTAT
GGAGTTTTAACGACGAACGCGTGGCGCGGGGGATTTTTGCCAGCCGCATTCCGGTAGTCAGCGCTGTCGGGCATGAAACC
GATGTGACCATTGCCGATTTTGTTGCCGATTTACGCGCACCAACACCGTCAGCCGCCGCCGAAGTGGTGAGCCGCAATCA
GCAAGAGTTACTGCGTCAGGTGCAGTCTGCGCAGCAACGGCTGGAAATGGCGATGGATTACTACCTCGCCAACCGCACGC
GACGTTTTACGCAGATCCATCACCGCTTGCAGCAGCAGCATCCACAGCTCCGGCTGGCGCGTCAGCAAACCACCCTTGAG
CGTCTGCAAAAGCGGATGAGCTTTGCGTTGGAGAATCAGCTTAAACGCGCCGGTCAGCAACAGCAGCGATTAACACTGCG
GCTGAATCAGCAAAACCCGCAACCGAAGATTCATCGCGCACAAACGCGGGTTCAGCAACTGGAATATCGTTTAGCGGAAA
ACTTGCGCGCGCAGCTTAGCGCTATGCGCGAACGCTTTGGTAACACAGTGACGCACCTCGAAGCGGTGAGTCCACTGTCC
ACACTGGCACGCGGTTATAGCGTTACCAGCGCTGCTGATGGCGCGGTGCTGAAACAGGTTAAGCAGGTGAAAGTGGGTGA
GACACTGACCACTCGCCTGGGCGATGGCGTAGTGATCAGTGAAGTGAGTGCTGTGACGAAAAGCCGCAAGCCGCGCAAAA
AAAACTAA

Upstream 100 bases:

>100_bases
GATTGCATCTACCCCTTTTTGCAAAAAATGCTTGCTATCCCCGGAGGGCGGGTTACTATCGACTGAATAACCTGCTGATT
TAGAATTTGATCTCGCTCAC

Downstream 100 bases:

>100_bases
TTACTCTATACGTATCTGTCTTTCGGGCACGGCGATATTTAAAGCTGGATAACCTTACCTGAAGCATGTAGCAAACCCGG
ATGTTTTCGCAGGCTGAATA

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDNAQVRCAMFRNSNRRVTFRPQHGQQV
LVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAKLQAEGLFDQQLKKTLPSPAHCVGVITSKTGAALHDILHVL
KRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANLRNECDVLIVGRGGGSLEDLWSFNDERVARGIFASRIPVVSAVGHET
DVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSAQQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTTLE
RLQKRMSFALENQLKRAGQQQQRLTLRLNQQNPQPKIHRAQTRVQQLEYRLAENLRAQLSAMRERFGNTVTHLEAVSPLS
TLARGYSVTSAADGAVLKQVKQVKVGETLTTRLGDGVVISEVSAVTKSRKPRKKN

Sequences:

>Translated_455_residues
MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDNAQVRCAMFRNSNRRVTFRPQHGQQV
LVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAKLQAEGLFDQQLKKTLPSPAHCVGVITSKTGAALHDILHVL
KRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANLRNECDVLIVGRGGGSLEDLWSFNDERVARGIFASRIPVVSAVGHET
DVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSAQQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTTLE
RLQKRMSFALENQLKRAGQQQQRLTLRLNQQNPQPKIHRAQTRVQQLEYRLAENLRAQLSAMRERFGNTVTHLEAVSPLS
TLARGYSVTSAADGAVLKQVKQVKVGETLTTRLGDGVVISEVSAVTKSRKPRKKN
>Mature_455_residues
MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDNAQVRCAMFRNSNRRVTFRPQHGQQV
LVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAKLQAEGLFDQQLKKTLPSPAHCVGVITSKTGAALHDILHVL
KRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANLRNECDVLIVGRGGGSLEDLWSFNDERVARGIFASRIPVVSAVGHET
DVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSAQQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTTLE
RLQKRMSFALENQLKRAGQQQQRLTLRLNQQNPQPKIHRAQTRVQQLEYRLAENLRAQLSAMRERFGNTVTHLEAVSPLS
TLARGYSVTSAADGAVLKQVKQVKVGETLTTRLGDGVVISEVSAVTKSRKPRKKN

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=454, Percent_Identity=92.511013215859, Blast_Score=840, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 51228; Mature: 51228

Theoretical pI: Translated: 10.65; Mature: 10.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDNAQVRC
CCCCCCCCEEEHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEEECCCCEEEE
AMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAK
EEEECCCCEEEECCCCCCEEEEEEEEEEECCCCCCEEHEEHHCCCCCHHHHHHHHHHHHH
LQAEGLFDQQLKKTLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYPTAVQGDD
HHHCCCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
APGQIVRAIELANLRNECDVLIVGRGGGSLEDLWSFNDERVARGIFASRIPVVSAVGHET
CHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHHCCHHHHCCCCC
DVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSAQQRLEMAMDYYLANRTRRFTQIH
CCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRLQQQHPQLRLARQQTTLERLQKRMSFALENQLKRAGQQQQRLTLRLNQQNPQPKIHRA
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCHHHHH
QTRVQQLEYRLAENLRAQLSAMRERFGNTVTHLEAVSPLSTLARGYSVTSAADGAVLKQV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
KQVKVGETLTTRLGDGVVISEVSAVTKSRKPRKKN
HHHHCCCHHHHHCCCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDNAQVRC
CCCCCCCCEEEHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEEECCCCEEEE
AMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAK
EEEECCCCEEEECCCCCCEEEEEEEEEEECCCCCCEEHEEHHCCCCCHHHHHHHHHHHHH
LQAEGLFDQQLKKTLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYPTAVQGDD
HHHCCCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
APGQIVRAIELANLRNECDVLIVGRGGGSLEDLWSFNDERVARGIFASRIPVVSAVGHET
CHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHHCCHHHHCCCCC
DVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSAQQRLEMAMDYYLANRTRRFTQIH
CCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRLQQQHPQLRLARQQTTLERLQKRMSFALENQLKRAGQQQQRLTLRLNQQNPQPKIHRA
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCHHHHH
QTRVQQLEYRLAENLRAQLSAMRERFGNTVTHLEAVSPLSTLARGYSVTSAADGAVLKQV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
KQVKVGETLTTRLGDGVVISEVSAVTKSRKPRKKN
HHHHCCCHHHHHCCCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA