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The map label for this gene is prtR [H]

Identifier: 218547977

GI number: 218547977

Start: 596825

End: 597511

Strand: Reverse

Name: prtR [H]

Synonym: EFER_0582

Alternate gene names: 218547977

Gene position: 597511-596825 (Counterclockwise)

Preceding gene: 218547989

Following gene: 218547975

Centisome position: 13.02

GC content: 40.03

Gene sequence:

>687_bases
GTGAAAACACTGGCAGAACGATTAAAGATAGGTAGAGAGATAGCTGGCATGAGCCAAGCTCAACTAGCTGAAAAAATTGG
ACTTTCACAACAATCTGTAGCCAAAATAGAGAATGGCGAAACTCTACAACCGCGCAAAATTAAAGAAATTGCAAAAGTTT
TAGGTGTATCACAAAAGTGGTTACAACTTGGTATTGAAGACAACGCATCCATACCTGATCTTGTTGTAAAAGAAGCAGAA
AGCACCGCATTAGACCCCGATATTTTCGTAAACATTCCTGTTTTAGATGTCGAGTTATCGGCAGGTAACGGATGTCTGGC
TGAAATAGTTGAATCAGCTATTGACTGGTTTCCGTTAAGAAGAGCAGATTTGAGAAAATCTGGCGTATGTGCATCTAATG
CCAAGATCGTAAAAATATGGGGGAACAGTTTATTACCGGTTCTCAATAATGGAGATCTTGTTGCCGTTGATATTTCTCAA
ACCGTTCCTATTCGTGATGGCGATCTTTATGCCGTACGAGATGGTGTATTGCTAAGGGTTAAAATACTTATCAACTTACC
TGACGGTGGCTTGATTCTTAGAAGCTTCAACAAAGATGAGTACCCAGATGAAATACTCACCTTTGAAGATAGACGAGCCA
GAATTCATGTTATAGGTAGGGTATTCTGGTCATCGCGAACTTGGTAA

Upstream 100 bases:

>100_bases
GTTGCAAGAATACAACATTAACAACTTTTATCACAACTTTTAGGTGTTGGAAAGCTAAAACATAAAGTTGTAACCTCATC
AAAAAAGAGAGGGATATGTT

Downstream 100 bases:

>100_bases
TGCATCGAAAAGCATTTCTTCAGAAATAATTTTAAGTTTTGCACCATTATCATCCCTATAAGATATAGCTTTTTCGATCT
TCCTTCCGTGACTTGAGAAT

Product: Cro/CI family transcriptional regulator

Products: NA

Alternate protein names: Pyocin repressor protein [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MKTLAERLKIGREIAGMSQAQLAEKIGLSQQSVAKIENGETLQPRKIKEIAKVLGVSQKWLQLGIEDNASIPDLVVKEAE
STALDPDIFVNIPVLDVELSAGNGCLAEIVESAIDWFPLRRADLRKSGVCASNAKIVKIWGNSLLPVLNNGDLVAVDISQ
TVPIRDGDLYAVRDGVLLRVKILINLPDGGLILRSFNKDEYPDEILTFEDRRARIHVIGRVFWSSRTW

Sequences:

>Translated_228_residues
MKTLAERLKIGREIAGMSQAQLAEKIGLSQQSVAKIENGETLQPRKIKEIAKVLGVSQKWLQLGIEDNASIPDLVVKEAE
STALDPDIFVNIPVLDVELSAGNGCLAEIVESAIDWFPLRRADLRKSGVCASNAKIVKIWGNSLLPVLNNGDLVAVDISQ
TVPIRDGDLYAVRDGVLLRVKILINLPDGGLILRSFNKDEYPDEILTFEDRRARIHVIGRVFWSSRTW
>Mature_228_residues
MKTLAERLKIGREIAGMSQAQLAEKIGLSQQSVAKIENGETLQPRKIKEIAKVLGVSQKWLQLGIEDNASIPDLVVKEAE
STALDPDIFVNIPVLDVELSAGNGCLAEIVESAIDWFPLRRADLRKSGVCASNAKIVKIWGNSLLPVLNNGDLVAVDISQ
TVPIRDGDLYAVRDGVLLRVKILINLPDGGLILRSFNKDEYPDEILTFEDRRARIHVIGRVFWSSRTW

Specific function: Represses the promoter activity of the prtN gene [H]

COG id: COG2932

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH cro/C1-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001387
- InterPro:   IPR010982
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF01381 HTH_3; PF00717 Peptidase_S24 [H]

EC number: NA

Molecular weight: Translated: 25205; Mature: 25205

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50943 HTH_CROC1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLAERLKIGREIAGMSQAQLAEKIGLSQQSVAKIENGETLQPRKIKEIAKVLGVSQKW
CCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHH
LQLGIEDNASIPDLVVKEAESTALDPDIFVNIPVLDVELSAGNGCLAEIVESAIDWFPLR
HEECCCCCCCCCHHHHHCCCCCCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHCCCC
RADLRKSGVCASNAKIVKIWGNSLLPVLNNGDLVAVDISQTVPIRDGDLYAVRDGVLLRV
HHHHHHCCCCCCCCEEEEEECCCCCEEECCCCEEEEECCCCCCCCCCCEEEECCCEEEEE
KILINLPDGGLILRSFNKDEYPDEILTFEDRRARIHVIGRVFWSSRTW
EEEEECCCCCEEEEECCCCCCCCHHEEECCCCEEEEEEEEEECCCCCC
>Mature Secondary Structure
MKTLAERLKIGREIAGMSQAQLAEKIGLSQQSVAKIENGETLQPRKIKEIAKVLGVSQKW
CCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHH
LQLGIEDNASIPDLVVKEAESTALDPDIFVNIPVLDVELSAGNGCLAEIVESAIDWFPLR
HEECCCCCCCCCHHHHHCCCCCCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHCCCC
RADLRKSGVCASNAKIVKIWGNSLLPVLNNGDLVAVDISQTVPIRDGDLYAVRDGVLLRV
HHHHHHCCCCCCCCEEEEEECCCCCEEECCCCEEEEECCCCCCCCCCCEEEECCCEEEEE
KILINLPDGGLILRSFNKDEYPDEILTFEDRRARIHVIGRVFWSSRTW
EEEEECCCCCEEEEECCCCCCCCHHEEECCCCEEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8444788; 10984043 [H]