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The map label for this gene is glsA1 [H]

Identifier: 218235289

GI number: 218235289

Start: 486752

End: 487681

Strand: Reverse

Name: glsA1 [H]

Synonym: BCB4264_A0502

Alternate gene names: 218235289

Gene position: 487681-486752 (Counterclockwise)

Preceding gene: 218233200

Following gene: 218234751

Centisome position: 9.0

GC content: 35.05

Gene sequence:

>930_bases
ATGCAGTGCATTGAAACAAACAACTTACAACAGTTGTTAGAACAAGTAAAACCATATACAAAAAAAGGAAAACTTGCTAC
TTATATCCCCGAACTAGGAAATGCAAATCCAGACGATTTAGGGATTGCCATTTTCCATAAAGAAACAGAATATATCCATG
CAGGCAACTCACAAACACTATTTACTCTTCAAAGTATTTCCAAAGTAATTACACTTGCCCTTGCCCTTTTAGAACGTGGT
GAAGAATATGTATTTTCTAAAGTTGGAATGGAACCAACGGGTGACCCATTTAATTCTATTATTAAGTTAGAAACAACAAG
TCCGTCCAAACCCCTTAATCCAATGATAAATGCAGGAGCATTAGCTATTACAAGCATGTTAGCAGGAAAAGATAACGAGG
AAAAAATGGAACGTATTCTTCATTTTGTACGTGAAATAACAGATAATCCTACTATTAATTATTCCTCTAAAGTTGCCGAT
TCAGAACTAGAGACAGCTTACCTAAACCGTTCACTTTGTTATTATATGAAACAAAACGGAATTATCGATTGTGATATTGA
AGAACTTATGGATTTATATACTCGTCAATGCGCAGTTGAAGTAAACTGCATCGATTTAGCACGTATCGGCTTAATTTTTG
CAATGGATGGATATGATCCTTATAAAAAGAAACAAATCATCCCTAAACATATTACAAAAATTTGCAAAACATTTATGGTC
ACATGTGGTATGTATAACGAATCTGGTGAATTTGCAATTCGTGTTGGTATTCCTGCAAAAAGCGGTGTAGCCGGTGGTAT
TTTTGGCTGCGTAAAAGGAGACATGGGAATCGGTATTTTCGGACCAGCTTTAGATGCAAACGGAAATAGTATTGCTGGTT
TTAAAATTCTTGAACTTCTTTCTGCTCAAGAAGGTTGGAGCATTTTTTAA

Upstream 100 bases:

>100_bases
GAACTTTCGTTTTATCATTCCACTTTTTCATGTTATTATTTATTTCCGAGCATATCGGGAAAAGTAAACTTAGTTAATTC
AAAATAGGAGCGTTGGTACT

Downstream 100 bases:

>100_bases
TCGCGAGTTATCCTGCTATACTAGCAGGATTTTTTATTTCGTCAAAACCTCACTTTTGTGAGTTATCAATCTTCTTATAA
AAACAGTGCTGAAAGTTTCT

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MQCIETNNLQQLLEQVKPYTKKGKLATYIPELGNANPDDLGIAIFHKETEYIHAGNSQTLFTLQSISKVITLALALLERG
EEYVFSKVGMEPTGDPFNSIIKLETTSPSKPLNPMINAGALAITSMLAGKDNEEKMERILHFVREITDNPTINYSSKVAD
SELETAYLNRSLCYYMKQNGIIDCDIEELMDLYTRQCAVEVNCIDLARIGLIFAMDGYDPYKKKQIIPKHITKICKTFMV
TCGMYNESGEFAIRVGIPAKSGVAGGIFGCVKGDMGIGIFGPALDANGNSIAGFKILELLSAQEGWSIF

Sequences:

>Translated_309_residues
MQCIETNNLQQLLEQVKPYTKKGKLATYIPELGNANPDDLGIAIFHKETEYIHAGNSQTLFTLQSISKVITLALALLERG
EEYVFSKVGMEPTGDPFNSIIKLETTSPSKPLNPMINAGALAITSMLAGKDNEEKMERILHFVREITDNPTINYSSKVAD
SELETAYLNRSLCYYMKQNGIIDCDIEELMDLYTRQCAVEVNCIDLARIGLIFAMDGYDPYKKKQIIPKHITKICKTFMV
TCGMYNESGEFAIRVGIPAKSGVAGGIFGCVKGDMGIGIFGPALDANGNSIAGFKILELLSAQEGWSIF
>Mature_309_residues
MQCIETNNLQQLLEQVKPYTKKGKLATYIPELGNANPDDLGIAIFHKETEYIHAGNSQTLFTLQSISKVITLALALLERG
EEYVFSKVGMEPTGDPFNSIIKLETTSPSKPLNPMINAGALAITSMLAGKDNEEKMERILHFVREITDNPTINYSSKVAD
SELETAYLNRSLCYYMKQNGIIDCDIEELMDLYTRQCAVEVNCIDLARIGLIFAMDGYDPYKKKQIIPKHITKICKTFMV
TCGMYNESGEFAIRVGIPAKSGVAGGIFGCVKGDMGIGIFGPALDANGNSIAGFKILELLSAQEGWSIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=291, Percent_Identity=34.7079037800687, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI20336214, Length=298, Percent_Identity=33.2214765100671, Blast_Score=163, Evalue=2e-40,
Organism=Escherichia coli, GI1787804, Length=301, Percent_Identity=38.5382059800665, Blast_Score=225, Evalue=2e-60,
Organism=Escherichia coli, GI1786693, Length=311, Percent_Identity=39.2282958199357, Blast_Score=219, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17507019, Length=298, Percent_Identity=34.2281879194631, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17532727, Length=277, Percent_Identity=35.7400722021661, Blast_Score=171, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI193204073, Length=282, Percent_Identity=32.9787234042553, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI193204075, Length=284, Percent_Identity=32.7464788732394, Blast_Score=154, Evalue=8e-38,
Organism=Drosophila melanogaster, GI281363241, Length=285, Percent_Identity=34.7368421052632, Blast_Score=171, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24653156, Length=285, Percent_Identity=34.7368421052632, Blast_Score=171, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24653162, Length=285, Percent_Identity=34.7368421052632, Blast_Score=171, Evalue=5e-43,
Organism=Drosophila melanogaster, GI116008307, Length=285, Percent_Identity=34.7368421052632, Blast_Score=171, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24653164, Length=285, Percent_Identity=34.7368421052632, Blast_Score=171, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24653166, Length=285, Percent_Identity=34.7368421052632, Blast_Score=171, Evalue=6e-43,
Organism=Drosophila melanogaster, GI281363239, Length=285, Percent_Identity=34.7368421052632, Blast_Score=171, Evalue=6e-43,
Organism=Drosophila melanogaster, GI24653158, Length=285, Percent_Identity=34.7368421052632, Blast_Score=171, Evalue=7e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 34050; Mature: 34050

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQCIETNNLQQLLEQVKPYTKKGKLATYIPELGNANPDDLGIAIFHKETEYIHAGNSQTL
CCCCCCCCHHHHHHHHCCCCCCCCEEEECCHHCCCCCCCCEEEEEECCCCEEECCCCCEE
FTLQSISKVITLALALLERGEEYVFSKVGMEPTGDPFNSIIKLETTSPSKPLNPMINAGA
EEHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHCEEEEEECCCCCCCCHHHCCHH
LAITSMLAGKDNEEKMERILHFVREITDNPTINYSSKVADSELETAYLNRSLCYYMKQNG
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHEEECCCC
IIDCDIEELMDLYTRQCAVEVNCIDLARIGLIFAMDGYDPYKKKQIIPKHITKICKTFMV
EEECCHHHHHHHHHHHHEEEECHHHHHHEEEEEEECCCCHHHHHCCCHHHHHHHHHHHHH
TCGMYNESGEFAIRVGIPAKSGVAGGIFGCVKGDMGIGIFGPALDANGNSIAGFKILELL
HCCCCCCCCCEEEEEECCCCCCCCCCHHHEECCCCCCEEECCCCCCCCCCCHHHHHHHHH
SAQEGWSIF
HCCCCCCCC
>Mature Secondary Structure
MQCIETNNLQQLLEQVKPYTKKGKLATYIPELGNANPDDLGIAIFHKETEYIHAGNSQTL
CCCCCCCCHHHHHHHHCCCCCCCCEEEECCHHCCCCCCCCEEEEEECCCCEEECCCCCEE
FTLQSISKVITLALALLERGEEYVFSKVGMEPTGDPFNSIIKLETTSPSKPLNPMINAGA
EEHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHCEEEEEECCCCCCCCHHHCCHH
LAITSMLAGKDNEEKMERILHFVREITDNPTINYSSKVADSELETAYLNRSLCYYMKQNG
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHEEECCCC
IIDCDIEELMDLYTRQCAVEVNCIDLARIGLIFAMDGYDPYKKKQIIPKHITKICKTFMV
EEECCHHHHHHHHHHHHEEEECHHHHHHEEEEEEECCCCHHHHHCCCHHHHHHHHHHHHH
TCGMYNESGEFAIRVGIPAKSGVAGGIFGCVKGDMGIGIFGPALDANGNSIAGFKILELL
HCCCCCCCCCEEEEEECCCCCCCCCCHHHEECCCCCCEEECCCCCCCCCCCHHHHHHHHH
SAQEGWSIF
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]