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The map label for this gene is pbpA [H]

Identifier: 213691001

GI number: 213691001

Start: 93233

End: 94699

Strand: Reverse

Name: pbpA [H]

Synonym: Blon_0079

Alternate gene names: 213691001

Gene position: 94699-93233 (Counterclockwise)

Preceding gene: 213691002

Following gene: 213691000

Centisome position: 3.34

GC content: 61.9

Gene sequence:

>1467_bases
ATGAACAAATATCTTCGTCAGCTTTTCACCGCCGTGGTCGCGCTGTTCGTGATTCTCGGCCTGTCGTCCACCATCATCAT
GGCGGTACGGGCCAACGCGCTGAACAACGATCCGCGCAACGCCCGTTCGCTGTACCACCAGCTCGGTGCCTACCGCGGTG
CCATCCTGGCCTCGGACGGCACGGTCATGGCCAAATCCGAGCCGGTCAACGACGCATTCAAATACCTGCGTACCTATTCC
AACGGTCCGCTGTATGCTCCGGTCACCGGCTTCTTCTCCATCAACCAGACCGCCGATCGCGGCCTGGAAGCCTCCCGCAG
CATGCTGCTCAACGGTGAGGCCGATTCATTGATCTGGCAGCGGGCCAAGGCCATGCTCACCGGCGCTACGAATCAGGGCG
CGTCCATCGAAACCTCCATCGACCCCAAGCTGCAGCAGGTTGCCTACGATCAGCTCGGTACGCGCGATGGTGCGGCGGTG
GCCATCGAAGTCAGCACCGGTCGTATCCTCGCCATGGTGAGCACGCCCAGTTATGATCCGAACAAACTGGCGACCCATGA
CACCAAAGCCGCGTCTCAGGCCTACAACGAACTTTCTGCGGGCCAAAATAGCCCACTAATCAACCGCGCCACCTCGCAGC
TGTACCCACCAGGGTCCACGTTCAAGACCATCGTCGCCTCGGCTGCGCTGGAAACCGGCGAATATCAGACGGACACGAAG
ATTCCTGCAGGCGCCGGCTACACGCTGCCCGGCACCGCCACACAGCTGCCGAACGCCGAGCATCAGGCCGACGGCGTCAA
CGGGCAGATCTCCCTGCAAGAGGCCGTCGCGTGGTCGTCCAACACCGCGTTCGCCCAGCTTGGCGTGAAACTCGGCGCGA
GCAAGGTTTCGGACATGGCCACCAAGCTCGGGTTTGGCAGCACCATCACCATTGACGGCACCGAATCCACGGGCACCCCG
ATGACGGCCACCGCGTCCACATTCCCCTCTGATCCGACCGACGACAAGCTTGCGCTGGCATCCATCGGCCAAGGCGACAC
CACGGCCACGCCGTTGCAGATGGCGATGGTCGCGCAGGCAATCGCCAACAATGGCAAACTGATGCAGCCCACGCTGGTCG
ATCGTGTGCGCGCCGCCGATCTCACCGTACTTTCGCAGACCAAACCGCAAACCATGGCCAATGCGTTCAACAAGGATTCC
GCAGACAAGCTCACCACGATGATGGAAAGCGTGGTGACCGAGGCCAATCCGCAGCTGGCCATCGACGGCATCAAGGTGGC
GGCCAAAACCGGTACCGCACAAATCGGTACCGACAACTCTGCCATCGACGGCTGGGTGATCGGTTTCGCGCCGGCGGACG
ATCCGCAGATCGCCGTCGCGGTGTTGGTGCATAACACAGATGTATACGGTTCGCTCGCCGCTGGCCCGATCATGCGCGCG
ATGATGCAGGAGGCTTTGCAGCAGTGA

Upstream 100 bases:

>100_bases
TTGTGGATACCACCACTCCGTCGTATACCGGCGCCGATGAACCGTACACGCCTACCGGCACGATTCCCCCGCTTCCTCCC
GTTAACGGAGGCACTCGCGT

Downstream 100 bases:

>100_bases
AACTTATCGAAGGACAGCTTATTCACCGCCGATATCGTCTTGATTCGCGTCTTGCGCAAGGCGGTATGGGCGAGGTCTGG
AAAGGCTACGATATTCAGCT

Product: Peptidoglycan glycosyltransferase

Products: NA

Alternate protein names: PBPA [H]

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MNKYLRQLFTAVVALFVILGLSSTIIMAVRANALNNDPRNARSLYHQLGAYRGAILASDGTVMAKSEPVNDAFKYLRTYS
NGPLYAPVTGFFSINQTADRGLEASRSMLLNGEADSLIWQRAKAMLTGATNQGASIETSIDPKLQQVAYDQLGTRDGAAV
AIEVSTGRILAMVSTPSYDPNKLATHDTKAASQAYNELSAGQNSPLINRATSQLYPPGSTFKTIVASAALETGEYQTDTK
IPAGAGYTLPGTATQLPNAEHQADGVNGQISLQEAVAWSSNTAFAQLGVKLGASKVSDMATKLGFGSTITIDGTESTGTP
MTATASTFPSDPTDDKLALASIGQGDTTATPLQMAMVAQAIANNGKLMQPTLVDRVRAADLTVLSQTKPQTMANAFNKDS
ADKLTTMMESVVTEANPQLAIDGIKVAAKTGTAQIGTDNSAIDGWVIGFAPADDPQIAVAVLVHNTDVYGSLAAGPIMRA
MMQEALQQ

Sequences:

>Translated_488_residues
MNKYLRQLFTAVVALFVILGLSSTIIMAVRANALNNDPRNARSLYHQLGAYRGAILASDGTVMAKSEPVNDAFKYLRTYS
NGPLYAPVTGFFSINQTADRGLEASRSMLLNGEADSLIWQRAKAMLTGATNQGASIETSIDPKLQQVAYDQLGTRDGAAV
AIEVSTGRILAMVSTPSYDPNKLATHDTKAASQAYNELSAGQNSPLINRATSQLYPPGSTFKTIVASAALETGEYQTDTK
IPAGAGYTLPGTATQLPNAEHQADGVNGQISLQEAVAWSSNTAFAQLGVKLGASKVSDMATKLGFGSTITIDGTESTGTP
MTATASTFPSDPTDDKLALASIGQGDTTATPLQMAMVAQAIANNGKLMQPTLVDRVRAADLTVLSQTKPQTMANAFNKDS
ADKLTTMMESVVTEANPQLAIDGIKVAAKTGTAQIGTDNSAIDGWVIGFAPADDPQIAVAVLVHNTDVYGSLAAGPIMRA
MMQEALQQ
>Mature_488_residues
MNKYLRQLFTAVVALFVILGLSSTIIMAVRANALNNDPRNARSLYHQLGAYRGAILASDGTVMAKSEPVNDAFKYLRTYS
NGPLYAPVTGFFSINQTADRGLEASRSMLLNGEADSLIWQRAKAMLTGATNQGASIETSIDPKLQQVAYDQLGTRDGAAV
AIEVSTGRILAMVSTPSYDPNKLATHDTKAASQAYNELSAGQNSPLINRATSQLYPPGSTFKTIVASAALETGEYQTDTK
IPAGAGYTLPGTATQLPNAEHQADGVNGQISLQEAVAWSSNTAFAQLGVKLGASKVSDMATKLGFGSTITIDGTESTGTP
MTATASTFPSDPTDDKLALASIGQGDTTATPLQMAMVAQAIANNGKLMQPTLVDRVRAADLTVLSQTKPQTMANAFNKDS
ADKLTTMMESVVTEANPQLAIDGIKVAAKTGTAQIGTDNSAIDGWVIGFAPADDPQIAVAVLVHNTDVYGSLAAGPIMRA
MMQEALQQ

Specific function: Cell wall formation. Plays an important role in cell division and cell shape maintenance by cross-linking adjacent peptidoglycan chains through transpeptidation [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Probable). Note=Localized to the division site (septum) along with newly synthesized peptidoglycan, between segregated nucleoids (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786854, Length=377, Percent_Identity=28.3819628647215, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI1786272, Length=435, Percent_Identity=25.7471264367816, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 51166; Mature: 51166

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKYLRQLFTAVVALFVILGLSSTIIMAVRANALNNDPRNARSLYHQLGAYRGAILASDG
CCHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCCCCCCHHHHHHHHHHHHHCCEEEECCC
TVMAKSEPVNDAFKYLRTYSNGPLYAPVTGFFSINQTADRGLEASRSMLLNGEADSLIWQ
EEEECCCCHHHHHHHHHHCCCCCEEEEEEEEEEECCHHHHCHHHHHHEEECCCHHHHHHH
RAKAMLTGATNQGASIETSIDPKLQQVAYDQLGTRDGAAVAIEVSTGRILAMVSTPSYDP
HHHHHHCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEECCCCCC
NKLATHDTKAASQAYNELSAGQNSPLINRATSQLYPPGSTFKTIVASAALETGEYQTDTK
CCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCC
IPAGAGYTLPGTATQLPNAEHQADGVNGQISLQEAVAWSSNTAFAQLGVKLGASKVSDMA
CCCCCCCCCCCCCCCCCCCHHHCCCCCCEEEHHHHHHCCCCCHHHHHHHHHCHHHHHHHH
TKLGFGSTITIDGTESTGTPMTATASTFPSDPTDDKLALASIGQGDTTATPLQMAMVAQA
HHHCCCCEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHH
IANNGKLMQPTLVDRVRAADLTVLSQTKPQTMANAFNKDSADKLTTMMESVVTEANPQLA
HHCCCCEECCHHHHHHHHCCEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEE
IDGIKVAAKTGTAQIGTDNSAIDGWVIGFAPADDPQIAVAVLVHNTDVYGSLAAGPIMRA
ECCEEEEEECCCEEECCCCCCCCCEEEEECCCCCCCEEEEEEEECCCCCCCHHHHHHHHH
MMQEALQQ
HHHHHHCC
>Mature Secondary Structure
MNKYLRQLFTAVVALFVILGLSSTIIMAVRANALNNDPRNARSLYHQLGAYRGAILASDG
CCHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCCCCCCHHHHHHHHHHHHHCCEEEECCC
TVMAKSEPVNDAFKYLRTYSNGPLYAPVTGFFSINQTADRGLEASRSMLLNGEADSLIWQ
EEEECCCCHHHHHHHHHHCCCCCEEEEEEEEEEECCHHHHCHHHHHHEEECCCHHHHHHH
RAKAMLTGATNQGASIETSIDPKLQQVAYDQLGTRDGAAVAIEVSTGRILAMVSTPSYDP
HHHHHHCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEECCCCCC
NKLATHDTKAASQAYNELSAGQNSPLINRATSQLYPPGSTFKTIVASAALETGEYQTDTK
CCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCC
IPAGAGYTLPGTATQLPNAEHQADGVNGQISLQEAVAWSSNTAFAQLGVKLGASKVSDMA
CCCCCCCCCCCCCCCCCCCHHHCCCCCCEEEHHHHHHCCCCCHHHHHHHHHCHHHHHHHH
TKLGFGSTITIDGTESTGTPMTATASTFPSDPTDDKLALASIGQGDTTATPLQMAMVAQA
HHHCCCCEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHH
IANNGKLMQPTLVDRVRAADLTVLSQTKPQTMANAFNKDSADKLTTMMESVVTEANPQLA
HHCCCCEECCHHHHHHHHCCEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEE
IDGIKVAAKTGTAQIGTDNSAIDGWVIGFAPADDPQIAVAVLVHNTDVYGSLAAGPIMRA
ECCEEEEEECCCEEECCCCCCCCCEEEEECCCCCCCEEEEEEEECCCCCCCHHHHHHHHH
MMQEALQQ
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA