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The map label for this gene is lysK [H]

Identifier: 212224548

GI number: 212224548

Start: 1270398

End: 1271978

Strand: Reverse

Name: lysK [H]

Synonym: TON_1397

Alternate gene names: 212224548

Gene position: 1271978-1270398 (Counterclockwise)

Preceding gene: 212224551

Following gene: 212224546

Centisome position: 68.84

GC content: 53.83

Gene sequence:

>1581_bases
ATGGTGCACTGGGCTGACTACATGGCTGAGAAGATCATCCAGGAAATGGGAGACAAGGAGGAGTACGTGGTAGAGAGCGG
CATAACCCCGAGTGGTTACGTTCACATAGGCAACTTCAGGGAGTTTTTCACTGCATATATTGTCGGTCATGCCCTCAGAG
ACAGGGGAAAGAAGGTTCGCCACATTCACATGTGGGACGACTACGACCGCTTTAGGAAGGTTCCCAAGAACGTTCCGAGC
GAGTGGAAGGAATACCTCACCATGCCTGTCCGTGAGGTTCCAGATCCCTGGGGCTGCCACAATAGCTATGCCGAGCACTT
TATGAGCCTCTTCGAGAAAGAAGTTGCCAAGCTTGGCATCGAGGCTGACTTCCTCTACGCGAGCGAGCTCTATAAGTCGG
GAGAGTATGCAGAGGACATCAGGCTTGCTCTGGAGAGGCGCAACGAGATAAAGGCAATCCTCGACAAGTACCGCGAGAGG
GCCAAGCAGCCGCCTCTCGAAGAGAGCTGGCAGCCTGTCATGGTTTACTGTCCCAAGTGCAGAAGGGAGGCTGAGTTCGT
TTCTTGGGACGGCGAGTGGAAGGTAGCCTATAAGTGTCCCCACTGCGGAAGCGAGGGAGAAACAGACATCCGCGAGGGCA
ACGTCAAGCTCCGCTGGCGTGTTGACTGGCCGATGCGCTGGGCACACTTCAGTGTGGACTTCGAGCCCGCTGGCAAGGAT
CACCTCGCCGCCGGTAGTTCCTACGATACTGGCAGCGAGATAGTGGAGAAGGTCTTCGGAAAGCCCGCTCCGCTAACGCT
CATGTACGAGTTTGTCGGCATAAAGGGAGAGAAGGGCAAGATGAGTGGAAGCAAGGGTAACGTGATTCTTCTCAGCGACC
TCTACGAGGTTCTTGAGCCCGGTATAATTCGCTTCATCTACGCCAAGCACAGGCCCAACAAGGAGCTTAAGATAGACCTC
GGCCTCGGTCTGCTCAACCTCTATGATGAGTTTGATAAGGTCGAGAGGATATACTTTGGCCTTGAGCACGCAAAGAACCC
CGAGGAGGAAGAGGAGCTCAAGAGAACCTATGAGCTCTCGATGCCGAAGGTTCCGGAGAGACTCATCGCTCAGGCACCTT
TCAGGTTCCTGGTTACACTCGTTCAGATGCCTCACCTCGACGAGGACGGCATAATTGAAGTCCTCAAGGAGCAGGGACAC
ATACCCAGAGAACTGAGTGAGGAGGACATCGGGAGGATAAGGCTCCGCATTGAATTGGCCAAGAACTGGATCGAGAAGTA
CGCGCCAGACAACGTTAAGTTCAGTATCCTAGAAAAGCCGCCGAAGGTTGAGCTTACGCCTGAGATAAAGGATGCTATTG
AGGAGGTGGCCAACTGGCTCGAGGCCAACGAAAGCTTCACCGTCGATGAGCTCAACAATATTATCTTCGACGCGGCCAAG
AAGCGCAGCATTCCGAGCAAAGAATGGTTCAAGGTGCTCTACAATCTCTTCATTGGTAAAGACAGAGGTCCAAAACTGGC
ACCGCTCCTCGCTTCAATGAACAGGGAGTTCGTCATCAAGCGCCTCCGCATGGAGGCCTGA

Upstream 100 bases:

>100_bases
TTACTATCAATGCTTATAAATTTTTCCGTCTTTTAGTTGTCATTGGGTCAGTGAGCTTAAACTTAAAAGCCCCTCCACCA
AGCTACCTCGGGTGAAGAAA

Downstream 100 bases:

>100_bases
TTTTATCACTTTTTTGGGGTGTACACTTGGAAGTAGCTATGCTCGTTGAGCTTTTCACTGTGGAGCTGTCTGAAATAGAG
CTTTGCGAGGAGTTCAACGG

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS [H]

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MVHWADYMAEKIIQEMGDKEEYVVESGITPSGYVHIGNFREFFTAYIVGHALRDRGKKVRHIHMWDDYDRFRKVPKNVPS
EWKEYLTMPVREVPDPWGCHNSYAEHFMSLFEKEVAKLGIEADFLYASELYKSGEYAEDIRLALERRNEIKAILDKYRER
AKQPPLEESWQPVMVYCPKCRREAEFVSWDGEWKVAYKCPHCGSEGETDIREGNVKLRWRVDWPMRWAHFSVDFEPAGKD
HLAAGSSYDTGSEIVEKVFGKPAPLTLMYEFVGIKGEKGKMSGSKGNVILLSDLYEVLEPGIIRFIYAKHRPNKELKIDL
GLGLLNLYDEFDKVERIYFGLEHAKNPEEEEELKRTYELSMPKVPERLIAQAPFRFLVTLVQMPHLDEDGIIEVLKEQGH
IPRELSEEDIGRIRLRIELAKNWIEKYAPDNVKFSILEKPPKVELTPEIKDAIEEVANWLEANESFTVDELNNIIFDAAK
KRSIPSKEWFKVLYNLFIGKDRGPKLAPLLASMNREFVIKRLRMEA

Sequences:

>Translated_526_residues
MVHWADYMAEKIIQEMGDKEEYVVESGITPSGYVHIGNFREFFTAYIVGHALRDRGKKVRHIHMWDDYDRFRKVPKNVPS
EWKEYLTMPVREVPDPWGCHNSYAEHFMSLFEKEVAKLGIEADFLYASELYKSGEYAEDIRLALERRNEIKAILDKYRER
AKQPPLEESWQPVMVYCPKCRREAEFVSWDGEWKVAYKCPHCGSEGETDIREGNVKLRWRVDWPMRWAHFSVDFEPAGKD
HLAAGSSYDTGSEIVEKVFGKPAPLTLMYEFVGIKGEKGKMSGSKGNVILLSDLYEVLEPGIIRFIYAKHRPNKELKIDL
GLGLLNLYDEFDKVERIYFGLEHAKNPEEEEELKRTYELSMPKVPERLIAQAPFRFLVTLVQMPHLDEDGIIEVLKEQGH
IPRELSEEDIGRIRLRIELAKNWIEKYAPDNVKFSILEKPPKVELTPEIKDAIEEVANWLEANESFTVDELNNIIFDAAK
KRSIPSKEWFKVLYNLFIGKDRGPKLAPLLASMNREFVIKRLRMEA
>Mature_526_residues
MVHWADYMAEKIIQEMGDKEEYVVESGITPSGYVHIGNFREFFTAYIVGHALRDRGKKVRHIHMWDDYDRFRKVPKNVPS
EWKEYLTMPVREVPDPWGCHNSYAEHFMSLFEKEVAKLGIEADFLYASELYKSGEYAEDIRLALERRNEIKAILDKYRER
AKQPPLEESWQPVMVYCPKCRREAEFVSWDGEWKVAYKCPHCGSEGETDIREGNVKLRWRVDWPMRWAHFSVDFEPAGKD
HLAAGSSYDTGSEIVEKVFGKPAPLTLMYEFVGIKGEKGKMSGSKGNVILLSDLYEVLEPGIIRFIYAKHRPNKELKIDL
GLGLLNLYDEFDKVERIYFGLEHAKNPEEEEELKRTYELSMPKVPERLIAQAPFRFLVTLVQMPHLDEDGIIEVLKEQGH
IPRELSEEDIGRIRLRIELAKNWIEKYAPDNVKFSILEKPPKVELTPEIKDAIEEVANWLEANESFTVDELNNIIFDAAK
KRSIPSKEWFKVLYNLFIGKDRGPKLAPLLASMNREFVIKRLRMEA

Specific function: Unknown

COG id: COG1384

COG function: function code J; Lysyl-tRNA synthetase (class I)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR002904
- InterPro:   IPR020754
- InterPro:   IPR020756
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01921 tRNA-synt_1f [H]

EC number: =6.1.1.6 [H]

Molecular weight: Translated: 61355; Mature: 61355

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHWADYMAEKIIQEMGDKEEYVVESGITPSGYVHIGNFREFFTAYIVGHALRDRGKKVR
CCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCEE
HIHMWDDYDRFRKVPKNVPSEWKEYLTMPVREVPDPWGCHNSYAEHFMSLFEKEVAKLGI
EEECCCCHHHHHHHHCCCCHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCC
EADFLYASELYKSGEYAEDIRLALERRNEIKAILDKYRERAKQPPLEESWQPVMVYCPKC
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHH
RREAEFVSWDGEWKVAYKCPHCGSEGETDIREGNVKLRWRVDWPMRWAHFSVDFEPAGKD
CCCCCEEECCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCEEEEEEEEECCCCCCC
HLAAGSSYDTGSEIVEKVFGKPAPLTLMYEFVGIKGEKGKMSGSKGNVILLSDLYEVLEP
CCCCCCCCCCHHHHHHHHCCCCCCCEEEHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHCC
GIIRFIYAKHRPNKELKIDLGLGLLNLYDEFDKVERIYFGLEHAKNPEEEEELKRTYELS
CCEEEHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
MPKVPERLIAQAPFRFLVTLVQMPHLDEDGIIEVLKEQGHIPRELSEEDIGRIRLRIELA
CCCCCHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCHHCHHHEEEHHHHH
KNWIEKYAPDNVKFSILEKPPKVELTPEIKDAIEEVANWLEANESFTVDELNNIIFDAAK
HHHHHHHCCCCCEEEEECCCCCCEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
KRSIPSKEWFKVLYNLFIGKDRGPKLAPLLASMNREFVIKRLRMEA
HCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure
MVHWADYMAEKIIQEMGDKEEYVVESGITPSGYVHIGNFREFFTAYIVGHALRDRGKKVR
CCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCEE
HIHMWDDYDRFRKVPKNVPSEWKEYLTMPVREVPDPWGCHNSYAEHFMSLFEKEVAKLGI
EEECCCCHHHHHHHHCCCCHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCC
EADFLYASELYKSGEYAEDIRLALERRNEIKAILDKYRERAKQPPLEESWQPVMVYCPKC
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHH
RREAEFVSWDGEWKVAYKCPHCGSEGETDIREGNVKLRWRVDWPMRWAHFSVDFEPAGKD
CCCCCEEECCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCEEEEEEEEECCCCCCC
HLAAGSSYDTGSEIVEKVFGKPAPLTLMYEFVGIKGEKGKMSGSKGNVILLSDLYEVLEP
CCCCCCCCCCHHHHHHHHCCCCCCCEEEHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHCC
GIIRFIYAKHRPNKELKIDLGLGLLNLYDEFDKVERIYFGLEHAKNPEEEEELKRTYELS
CCEEEHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
MPKVPERLIAQAPFRFLVTLVQMPHLDEDGIIEVLKEQGHIPRELSEEDIGRIRLRIELA
CCCCCHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCHHCHHHEEEHHHHH
KNWIEKYAPDNVKFSILEKPPKVELTPEIKDAIEEVANWLEANESFTVDELNNIIFDAAK
HHHHHHHCCCCCEEEEECCCCCCEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
KRSIPSKEWFKVLYNLFIGKDRGPKLAPLLASMNREFVIKRLRMEA
HCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA