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The map label for this gene is etfA [H]

Identifier: 209552153

GI number: 209552153

Start: 258681

End: 259613

Strand: Reverse

Name: etfA [H]

Synonym: Rleg2_6308

Alternate gene names: 209552153

Gene position: 259613-258681 (Counterclockwise)

Preceding gene: 209552154

Following gene: 209552152

Centisome position: 84.09

GC content: 61.2

Gene sequence:

>933_bases
ATGGCCATTCTTCTTCTGGCTGACCACGACAATGCAACCCTTTCCGACCAGACCGGCAAGGCACTGACGGCCGCTTCCAA
GATCGGGAAGGAAGTGCATGTGCTGGTCGCGGGCAAAGCCGCCTCGCTCGTAGCCGACGCAGCGTCCAGACTAAGCGGCG
TCTCCAAGGTGCTGCTCGCCGAAAGCGATGCTTTTGCCGACAATCTGGCGGAGCCCCTGGCCGATCTGATCGTCTCGCTC
GCGGGCAGCTACGACACGATTATTGCGGCTGCGACCTCAACCGGCAAGAACGTCTTGCCGCGCGTCGCAGCCCTGCTCGA
TGTTGCTCAGGTTTCAGAAATCATCGAAGTCGTTTCCGCAGACACCTTCAAGCGGCCGATCTATGCGGGCAATGCCATCC
AGACTGTTCAGGCGAGTGATGCCAGACGAGTCATCACCGTCCGCACCGCCTCGTTTTCCCCGGCCTCCCAAGGCCCTGCT
GCTGCCGTCGAATTGATTTCGACGGCAGCCTTTTCTTCCGATCTGTCGACCGCGGTCTCCACCTCCATAGTGACGTCGGA
GCGGCCCGACCTCAACTCAGCCAGGGTTGTGATCGCCGGAGGCCGAGCACTTGGCTCCGCCGAGAAATTCCAGGAAGTCA
TCCTGCCGGTCGCCGACAAGCTCGGTGCGGCCGTTGGTGCCTCGCGCGCTGCGGTCGATGCAGGCTACGCTCCGAACGAC
TGGCAGGTCGGACAGACTGGCAAGGTCGTTGCTCCGCAGCTTTACATTGCCTGCGGCATTTCGGGTGCCATCCAGCATCT
TGCCGGCATGAAGGATTCGAAGGTCATCGTCGCCATCAACAAGGACGAGGAAGCGCCGATCTTCCAGGTCGCCGACTACG
GTCTCGTCGGCGACCTCTTCGAAATCCTCCCCGAGCTGCAGAAGATACTCTAG

Upstream 100 bases:

>100_bases
GGCCGCAAGGCGGGCGTCAAGGTCGAGTCGGTCGCCGAACTGGTCGAGAAGCTCAAGACCGAGGCCGGCGTCCTCTAAGG
TTCGAGAAAGGAATATATCG

Downstream 100 bases:

>100_bases
GAGGAAGCTCCCTTGCAAAAGCTCGGTGGCCTCGTGATGCGGAACGACGATCCCTTGCTAAGGGATCCGTCTGTTGAAGA
ACTCGCGCCGGCCAGGCGGG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MAILLLADHDNATLSDQTGKALTAASKIGKEVHVLVAGKAASLVADAASRLSGVSKVLLAESDAFADNLAEPLADLIVSL
AGSYDTIIAAATSTGKNVLPRVAALLDVAQVSEIIEVVSADTFKRPIYAGNAIQTVQASDARRVITVRTASFSPASQGPA
AAVELISTAAFSSDLSTAVSTSIVTSERPDLNSARVVIAGGRALGSAEKFQEVILPVADKLGAAVGASRAAVDAGYAPND
WQVGQTGKVVAPQLYIACGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVGDLFEILPELQKIL

Sequences:

>Translated_310_residues
MAILLLADHDNATLSDQTGKALTAASKIGKEVHVLVAGKAASLVADAASRLSGVSKVLLAESDAFADNLAEPLADLIVSL
AGSYDTIIAAATSTGKNVLPRVAALLDVAQVSEIIEVVSADTFKRPIYAGNAIQTVQASDARRVITVRTASFSPASQGPA
AAVELISTAAFSSDLSTAVSTSIVTSERPDLNSARVVIAGGRALGSAEKFQEVILPVADKLGAAVGASRAAVDAGYAPND
WQVGQTGKVVAPQLYIACGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVGDLFEILPELQKIL
>Mature_309_residues
AILLLADHDNATLSDQTGKALTAASKIGKEVHVLVAGKAASLVADAASRLSGVSKVLLAESDAFADNLAEPLADLIVSLA
GSYDTIIAAATSTGKNVLPRVAALLDVAQVSEIIEVVSADTFKRPIYAGNAIQTVQASDARRVITVRTASFSPASQGPAA
AVELISTAAFSSDLSTAVSTSIVTSERPDLNSARVVIAGGRALGSAEKFQEVILPVADKLGAAVGASRAAVDAGYAPNDW
QVGQTGKVVAPQLYIACGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVGDLFEILPELQKIL

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=309, Percent_Identity=51.1326860841424, Blast_Score=297, Evalue=7e-81,
Organism=Homo sapiens, GI189181759, Length=275, Percent_Identity=52, Blast_Score=271, Evalue=8e-73,
Organism=Escherichia coli, GI1786226, Length=192, Percent_Identity=36.4583333333333, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787990, Length=267, Percent_Identity=30.7116104868914, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082157, Length=247, Percent_Identity=29.5546558704453, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17506929, Length=305, Percent_Identity=53.4426229508197, Blast_Score=313, Evalue=6e-86,
Organism=Saccharomyces cerevisiae, GI6325261, Length=291, Percent_Identity=46.3917525773196, Blast_Score=249, Evalue=3e-67,
Organism=Drosophila melanogaster, GI17136898, Length=306, Percent_Identity=55.8823529411765, Blast_Score=317, Evalue=5e-87,
Organism=Drosophila melanogaster, GI24652801, Length=306, Percent_Identity=55.8823529411765, Blast_Score=317, Evalue=5e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31758; Mature: 31627

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILLLADHDNATLSDQTGKALTAASKIGKEVHVLVAGKAASLVADAASRLSGVSKVLLA
CEEEEEECCCCCEECCCCCHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHC
ESDAFADNLAEPLADLIVSLAGSYDTIIAAATSTGKNVLPRVAALLDVAQVSEIIEVVSA
CCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DTFKRPIYAGNAIQTVQASDARRVITVRTASFSPASQGPAAAVELISTAAFSSDLSTAVS
HHHCCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TSIVTSERPDLNSARVVIAGGRALGSAEKFQEVILPVADKLGAAVGASRAAVDAGYAPND
HHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
WQVGQTGKVVAPQLYIACGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVGDLF
CCCCCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCHHHHHH
EILPELQKIL
HHHHHHHHHC
>Mature Secondary Structure 
AILLLADHDNATLSDQTGKALTAASKIGKEVHVLVAGKAASLVADAASRLSGVSKVLLA
EEEEEECCCCCEECCCCCHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHC
ESDAFADNLAEPLADLIVSLAGSYDTIIAAATSTGKNVLPRVAALLDVAQVSEIIEVVSA
CCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DTFKRPIYAGNAIQTVQASDARRVITVRTASFSPASQGPAAAVELISTAAFSSDLSTAVS
HHHCCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TSIVTSERPDLNSARVVIAGGRALGSAEKFQEVILPVADKLGAAVGASRAAVDAGYAPND
HHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
WQVGQTGKVVAPQLYIACGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVGDLF
CCCCCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCHHHHHH
EILPELQKIL
HHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8599534; 12597275 [H]