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The map label for this gene is hupA [H]

Identifier: 209552051

GI number: 209552051

Start: 140858

End: 141136

Strand: Reverse

Name: hupA [H]

Synonym: Rleg2_6198

Alternate gene names: 209552051

Gene position: 141136-140858 (Counterclockwise)

Preceding gene: 209552069

Following gene: 209552039

Centisome position: 45.71

GC content: 57.71

Gene sequence:

>279_bases
ATGACCACGACCAACGATATTGCCGACAAGATCGCGACCGAACACAGCCTGACAAAGACGCAGGGGAAAGCCATCGTCGA
GGCGGTAATCGCTTCCATCACCGAAGCCGCAGTGGCCGGCAATGAGACGTCGTTGCCCGGCTTCGGTAAATTCAAGGTAA
AGGAAACGCCGGAGCGCGACGCCCGCAATCCTGCGACCGGTGCAACGATCAAGGTTGCCGCGGCCAAGAAGCTGGCATTC
ACGCCAGCTAAGGCCTTGAAAGACGCACTGAACAAGTAA

Upstream 100 bases:

>100_bases
GGAGATCCGGGGCTTTGCGAACGATTTGCCGCAGCGTGTCGATGACAGGTCCTGTTGGCAATGGCAGTGATTCTGCATCT
GACACGATGCGGAGAAGAAA

Downstream 100 bases:

>100_bases
TCTTTCTGGCCAAGCAAAAGAATAGCCCGGCGCCGTGCCGGGCTATTTTCGTTCTTGGTTTGCGTCAGCGGGCGGATGTC
CCGTTGAGAACATCCTGGAT

Product: histone family protein DNA-binding protein

Products: NA

Alternate protein names: HU-2; NS2 [H]

Number of amino acids: Translated: 92; Mature: 91

Protein sequence:

>92_residues
MTTTNDIADKIATEHSLTKTQGKAIVEAVIASITEAAVAGNETSLPGFGKFKVKETPERDARNPATGATIKVAAAKKLAF
TPAKALKDALNK

Sequences:

>Translated_92_residues
MTTTNDIADKIATEHSLTKTQGKAIVEAVIASITEAAVAGNETSLPGFGKFKVKETPERDARNPATGATIKVAAAKKLAF
TPAKALKDALNK
>Mature_91_residues
TTTNDIADKIATEHSLTKTQGKAIVEAVIASITEAAVAGNETSLPGFGKFKVKETPERDARNPATGATIKVAAAKKLAFT
PAKALKDALNK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1790433, Length=85, Percent_Identity=49.4117647058824, Blast_Score=76, Evalue=3e-16,
Organism=Escherichia coli, GI1786644, Length=87, Percent_Identity=44.8275862068966, Blast_Score=72, Evalue=1e-14,

Paralogues:

None

Copy number: 1380 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9566; Mature: 9435

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTNDIADKIATEHSLTKTQGKAIVEAVIASITEAAVAGNETSLPGFGKFKVKETPERD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCC
ARNPATGATIKVAAAKKLAFTPAKALKDALNK
CCCCCCCCEEEEECHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure 
TTTNDIADKIATEHSLTKTQGKAIVEAVIASITEAAVAGNETSLPGFGKFKVKETPERD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCC
ARNPATGATIKVAAAKKLAFTPAKALKDALNK
CCCCCCCCEEEEECHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]