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The map label for this gene is dsdC [H]

Identifier: 209550499

GI number: 209550499

Start: 2979095

End: 2980033

Strand: Direct

Name: dsdC [H]

Synonym: Rleg2_2922

Alternate gene names: 209550499

Gene position: 2979095-2980033 (Clockwise)

Preceding gene: 209550495

Following gene: 209550500

Centisome position: 65.65

GC content: 64.64

Gene sequence:

>939_bases
ATGGTTCGCCGCTTCTATGGTCTGCCGTCCCTCACCGCGCTTGCCACTTTCGAGGCCTCGGCACGGCACGGCAATTTCAC
CCTGGCGGCAGCCGAGCTCAACGTCACGACAGGGGCCGTCAGCCGGCAGATCAAGTCGATCGAGCAGGAGCTCGGCGTTG
CTCTTTTCCTGCGCACCGGCAAAGGGGTGATGCTGACCGCACCGGCCGAGGATTTGTACCGGGCGCTGGCAACCGGTTTT
GCCAGAGCGTCCGAAGTCGTCAATTCGATCAAGCAGGGCAACAGCGCCCGCAACGTGACGATTGCCTGCAGCGACGTGTT
CGGGACGATGTGGCTTATTCCCCGGATGCCGGATTTCTGGCGGCGCTTCACCGATATATCCGTCGATCACCTGATCGGCG
ACAACTTCAAGACCTTCCGCCCATCGCAGCTGGAGCTGCGCATCCGCTACGGATCGGGAAAATGGATCGACGAGACGGCG
GAATTCCTGTTCGACGACTGTCTCTATCCGGTCTGCAGTCCGGGGTTTGCCGAAAAGCATGCCGGCGCCTCGGCGGCCGA
TCTTGCCGATCTGCCGCTGTTGAATGTCGAGTGGGTCGAGCCCGGCTGGACCGGCTGGGAAGAGGTGCTGGCGCGCGGCG
GCGTGCCCTATCACGCCGCCAGCGGCAGACGCTTCGGCAAGTTCAGCGTCGCGCTCCAGGCTGCCATGGCCGACCAGGGC
CTGGTCGTCGGCTGGCACCGCCTGGTCGGCCCCCTGGTGGAAAAGGGGGATCTGGTGCGCTTCACCGACCTGGTCGTTCC
CGACCCTGGGGCCTATTACCTCACCTGGAACAGCACCCGCGCGCTGCCCGCCGCTGCGCTGTCGCTGCGCGACTGGATCA
GGATGCTCGCCGAAGAGGAAAGAAGGACGCCGATGCCTCTGGCGCGGCCAATTCCCTAA

Upstream 100 bases:

>100_bases
TGCGTTGAGTTAAACTCAAGACAAACGGGTTTGCCTGCGTTATCATGGCGGAAATATCAACACCGCGCTGACCGGCGCCG
GGAATAGACGGGGAAGATCA

Downstream 100 bases:

>100_bases
AACCGTCCGGATGGTGGCTTTCTCGCGGCCTGGGCTCGGCGGCTGAATCGCCGGCGTTGCCACCGAGGACCCACGACGCA
TCCAATGGCAGTCGTGGCAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: D-serine deaminase activator [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MVRRFYGLPSLTALATFEASARHGNFTLAAAELNVTTGAVSRQIKSIEQELGVALFLRTGKGVMLTAPAEDLYRALATGF
ARASEVVNSIKQGNSARNVTIACSDVFGTMWLIPRMPDFWRRFTDISVDHLIGDNFKTFRPSQLELRIRYGSGKWIDETA
EFLFDDCLYPVCSPGFAEKHAGASAADLADLPLLNVEWVEPGWTGWEEVLARGGVPYHAASGRRFGKFSVALQAAMADQG
LVVGWHRLVGPLVEKGDLVRFTDLVVPDPGAYYLTWNSTRALPAAALSLRDWIRMLAEEERRTPMPLARPIP

Sequences:

>Translated_312_residues
MVRRFYGLPSLTALATFEASARHGNFTLAAAELNVTTGAVSRQIKSIEQELGVALFLRTGKGVMLTAPAEDLYRALATGF
ARASEVVNSIKQGNSARNVTIACSDVFGTMWLIPRMPDFWRRFTDISVDHLIGDNFKTFRPSQLELRIRYGSGKWIDETA
EFLFDDCLYPVCSPGFAEKHAGASAADLADLPLLNVEWVEPGWTGWEEVLARGGVPYHAASGRRFGKFSVALQAAMADQG
LVVGWHRLVGPLVEKGDLVRFTDLVVPDPGAYYLTWNSTRALPAAALSLRDWIRMLAEEERRTPMPLARPIP
>Mature_312_residues
MVRRFYGLPSLTALATFEASARHGNFTLAAAELNVTTGAVSRQIKSIEQELGVALFLRTGKGVMLTAPAEDLYRALATGF
ARASEVVNSIKQGNSARNVTIACSDVFGTMWLIPRMPDFWRRFTDISVDHLIGDNFKTFRPSQLELRIRYGSGKWIDETA
EFLFDDCLYPVCSPGFAEKHAGASAADLADLPLLNVEWVEPGWTGWEEVLARGGVPYHAASGRRFGKFSVALQAAMADQG
LVVGWHRLVGPLVEKGDLVRFTDLVVPDPGAYYLTWNSTRALPAAALSLRDWIRMLAEEERRTPMPLARPIP

Specific function: Regulates the expression of the dsd operon for D-serine deaminase (dsdA) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788706, Length=271, Percent_Identity=31.3653136531365, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1789173, Length=299, Percent_Identity=30.1003344481605, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1786448, Length=299, Percent_Identity=26.7558528428094, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011781
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34430; Mature: 34430

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRRFYGLPSLTALATFEASARHGNFTLAAAELNVTTGAVSRQIKSIEQELGVALFLRTG
CCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHCCEEEEEECC
KGVMLTAPAEDLYRALATGFARASEVVNSIKQGNSARNVTIACSDVFGTMWLIPRMPDFW
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHCCCHHHH
RRFTDISVDHLIGDNFKTFRPSQLELRIRYGSGKWIDETAEFLFDDCLYPVCSPGFAEKH
HHHHCCCHHHHHCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
AGASAADLADLPLLNVEWVEPGWTGWEEVLARGGVPYHAASGRRFGKFSVALQAAMADQG
CCCCHHHHHCCCCEEEEEECCCCCCHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHCCCC
LVVGWHRLVGPLVEKGDLVRFTDLVVPDPGAYYLTWNSTRALPAAALSLRDWIRMLAEEE
EEEEHHHHHHHHHCCCCEEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
RRTPMPLARPIP
CCCCCCCCCCCC
>Mature Secondary Structure
MVRRFYGLPSLTALATFEASARHGNFTLAAAELNVTTGAVSRQIKSIEQELGVALFLRTG
CCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHCCEEEEEECC
KGVMLTAPAEDLYRALATGFARASEVVNSIKQGNSARNVTIACSDVFGTMWLIPRMPDFW
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHCCCHHHH
RRFTDISVDHLIGDNFKTFRPSQLELRIRYGSGKWIDETAEFLFDDCLYPVCSPGFAEKH
HHHHCCCHHHHHCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
AGASAADLADLPLLNVEWVEPGWTGWEEVLARGGVPYHAASGRRFGKFSVALQAAMADQG
CCCCHHHHHCCCCEEEEEECCCCCCHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHCCCC
LVVGWHRLVGPLVEKGDLVRFTDLVVPDPGAYYLTWNSTRALPAAALSLRDWIRMLAEEE
EEEEHHHHHHHHHCCCCEEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
RRTPMPLARPIP
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592420; 9205837; 9278503 [H]