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The map label for this gene is idhA [H]

Identifier: 209550495

GI number: 209550495

Start: 2974289

End: 2975281

Strand: Direct

Name: idhA [H]

Synonym: Rleg2_2918

Alternate gene names: 209550495

Gene position: 2974289-2975281 (Clockwise)

Preceding gene: 209550493

Following gene: 209550499

Centisome position: 65.54

GC content: 64.05

Gene sequence:

>993_bases
ATGACAGTGAGATTTGGTCTTCTCGGCGCCGGCCGCATCGGCAAGGTTCACGCGAAAGCCGTCAGCGGCGACGCCAATGC
GACGCTCGTCGCGGTGGCCGACGCCTTTCCGCAGGCGGCCGACGCCATTGCTTCGGCCTATGGCTGCGAAGTCCGCACCA
TCGAGGCGATCGAGGCAGCCAAGGATATCGACGCCGTCGTCATCTGCACGCCGACCGATACCCATGCCGACCTGATCGAG
CGCTTCGCCCGCGCCGGCAAGGCGATCTTCTGCGAAAAGCCTGTTGATCTCGACGTTGCCCGCGTCAAGGCCTGCATCAA
GGTGGTGGAAGAGACCGGCGCCAAGCTGATGGTCGGCTTCAACCGCCGCTTCGACCCGCATTTCATGGCGGTGCGCAAGG
TGATCGACGACGGCAAGATCGGCGATGTCGAAATGGTGACGATCACCTCGCGCGACCCCGGCGCCCCGCCGGTGGATTAC
ATCAAGCGCTCGGGCGGCATCTTTCGCGACATGACGATCCACGATTTCGACATGGCCCGCTTCCTGCTCGGCGAAGAGCC
GGTTTCGGTGCTGGCAACCGCCGCCGTCCTCGTCGAGAAGGCGATCGGCGAAGCCGGCGACTATGACAGCGTTTCGGTGA
TCCTGCAGACCAAATCCGGCAAGCAGGCCGTCATTTCCAACTCCCGCCGCGCCACCTATGGCTACGACCAGCGCATCGAA
GTGCACGGCGCCAAGGGCATGGCCGCAGCCGAAAACCAGCGCCCGGTCTCGATCGAAGTCGCCAACGGCGACGGCTATAC
CCGCCCGCCGCTGCATGATTTCTTCATGACCCGCTACACCGAAGCCTACGCCAACGAAATCGCCGCCTTCATCGCCGCGA
TCGAAAAGGGCACGAAGATTTCGCCGTCCGGCGCCGATGGCCTGGCGGCTCTGGTGCTCGCCGATGCGGCGGTGCAGTCG
GTCAAGGAAGGCAAACTGGTCAAGATCGGCTGA

Upstream 100 bases:

>100_bases
TGAAAGAGCCGCGGGCTTGACGCCGCGTGGAGAAGATGGAATGAAAATTCCAGATTTTGGGTAATTCGGTTTATTTGTTC
CGAATTCAATGGAGGTTGCT

Downstream 100 bases:

>100_bases
CGCATCGGCTCGATCGAAATCGATCGCAGGAAAGATGCGCCTTCTTTGGTTCATCATGAGATGGCCGGGCACTCGCCCGG
CCATTTTGCGTTTGTGGCAA

Product: oxidoreductase domain-containing protein

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI-dehydrogenase [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTVRFGLLGAGRIGKVHAKAVSGDANATLVAVADAFPQAADAIASAYGCEVRTIEAIEAAKDIDAVVICTPTDTHADLIE
RFARAGKAIFCEKPVDLDVARVKACIKVVEETGAKLMVGFNRRFDPHFMAVRKVIDDGKIGDVEMVTITSRDPGAPPVDY
IKRSGGIFRDMTIHDFDMARFLLGEEPVSVLATAAVLVEKAIGEAGDYDSVSVILQTKSGKQAVISNSRRATYGYDQRIE
VHGAKGMAAAENQRPVSIEVANGDGYTRPPLHDFFMTRYTEAYANEIAAFIAAIEKGTKISPSGADGLAALVLADAAVQS
VKEGKLVKIG

Sequences:

>Translated_330_residues
MTVRFGLLGAGRIGKVHAKAVSGDANATLVAVADAFPQAADAIASAYGCEVRTIEAIEAAKDIDAVVICTPTDTHADLIE
RFARAGKAIFCEKPVDLDVARVKACIKVVEETGAKLMVGFNRRFDPHFMAVRKVIDDGKIGDVEMVTITSRDPGAPPVDY
IKRSGGIFRDMTIHDFDMARFLLGEEPVSVLATAAVLVEKAIGEAGDYDSVSVILQTKSGKQAVISNSRRATYGYDQRIE
VHGAKGMAAAENQRPVSIEVANGDGYTRPPLHDFFMTRYTEAYANEIAAFIAAIEKGTKISPSGADGLAALVLADAAVQS
VKEGKLVKIG
>Mature_329_residues
TVRFGLLGAGRIGKVHAKAVSGDANATLVAVADAFPQAADAIASAYGCEVRTIEAIEAAKDIDAVVICTPTDTHADLIER
FARAGKAIFCEKPVDLDVARVKACIKVVEETGAKLMVGFNRRFDPHFMAVRKVIDDGKIGDVEMVTITSRDPGAPPVDYI
KRSGGIFRDMTIHDFDMARFLLGEEPVSVLATAAVLVEKAIGEAGDYDSVSVILQTKSGKQAVISNSRRATYGYDQRIEV
HGAKGMAAAENQRPVSIEVANGDGYTRPPLHDFFMTRYTEAYANEIAAFIAAIEKGTKISPSGADGLAALVLADAAVQSV
KEGKLVKIG

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87082405, Length=251, Percent_Identity=25.8964143426295, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787574, Length=218, Percent_Identity=26.1467889908257, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081947, Length=285, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789848, Length=131, Percent_Identity=29.0076335877863, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24581117, Length=239, Percent_Identity=23.8493723849372, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 35073; Mature: 34942

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRFGLLGAGRIGKVHAKAVSGDANATLVAVADAFPQAADAIASAYGCEVRTIEAIEAA
CEEEEEEEECCCCCEEEEEEECCCCCEEEEEEEHHCHHHHHHHHHHHCCCEEEHHHHHHH
KDIDAVVICTPTDTHADLIERFARAGKAIFCEKPVDLDVARVKACIKVVEETGAKLMVGF
CCCCEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEC
NRRFDPHFMAVRKVIDDGKIGDVEMVTITSRDPGAPPVDYIKRSGGIFRDMTIHDFDMAR
CCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHCCCEEEECEECHHHHHH
FLLGEEPVSVLATAAVLVEKAIGEAGDYDSVSVILQTKSGKQAVISNSRRATYGYDQRIE
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHCCCCCCCCCCCCEEE
VHGAKGMAAAENQRPVSIEVANGDGYTRPPLHDFFMTRYTEAYANEIAAFIAAIEKGTKI
EECCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
SPSGADGLAALVLADAAVQSVKEGKLVKIG
CCCCCCHHHHHHHHHHHHHHHHCCCEEEEC
>Mature Secondary Structure 
TVRFGLLGAGRIGKVHAKAVSGDANATLVAVADAFPQAADAIASAYGCEVRTIEAIEAA
EEEEEEEECCCCCEEEEEEECCCCCEEEEEEEHHCHHHHHHHHHHHCCCEEEHHHHHHH
KDIDAVVICTPTDTHADLIERFARAGKAIFCEKPVDLDVARVKACIKVVEETGAKLMVGF
CCCCEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEC
NRRFDPHFMAVRKVIDDGKIGDVEMVTITSRDPGAPPVDYIKRSGGIFRDMTIHDFDMAR
CCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHCCCEEEECEECHHHHHH
FLLGEEPVSVLATAAVLVEKAIGEAGDYDSVSVILQTKSGKQAVISNSRRATYGYDQRIE
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHCCCCCCCCCCCCEEE
VHGAKGMAAAENQRPVSIEVANGDGYTRPPLHDFFMTRYTEAYANEIAAFIAAIEKGTKI
EECCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
SPSGADGLAALVLADAAVQSVKEGKLVKIG
CCCCCCHHHHHHHHHHHHHHHHCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9802033; 11481431 [H]