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The map label for this gene is gbpR [H]

Identifier: 209550492

GI number: 209550492

Start: 2972174

End: 2973181

Strand: Direct

Name: gbpR [H]

Synonym: Rleg2_2915

Alternate gene names: 209550492

Gene position: 2972174-2973181 (Clockwise)

Preceding gene: 209550485

Following gene: 209550493

Centisome position: 65.5

GC content: 61.41

Gene sequence:

>1008_bases
ATGACGATTGTTTCAGAGCCCATTTCGATGGATCATGTCGATATCCACAGCGATAGTTTCGGCAATGACAACCTTTTACG
TGCAGGACTTAAGCTGAATCACCTGCGGATGATCGTCGCAATCGAAGATAGCGGACAGATTTCCGCAGCTGCGGAAGTCC
TGAACATTTCACAGCCCGCCGCATCGCGCATGCTGTCCGAAATGGAATCGATCACCAAGACTCAGCTCTATGAACGCGTC
GCCCGCGGCGTGGTGCTGACGACCTTCGGCGCAGCACTTGCCAGACGCGCGCGAAAGATCCTCCTGGAGCTGCGCGAGGC
AAGCCGCGAGATCGGCGAACTGAAGAGCGGCAAGGGCGGCTCGGTCTTCATCGGCGCGGTGACGGCGCCGGCCATGAGCC
TCGTCGTGCCGGCGATCAACCGGGTGCGCAAGGCCTATCCCGGCATCGAGATCAACATCCAGGTGGAGACCAGCAACGTG
CTCGCCCGCGAGCTGCTCGCCGCCCGCCACGACTTCATCATCAGCCGCATTCCCGACGATCTCAATCCGCGCCTGTTCGA
GGTGACGGAGATCGGCATCGAGCGCGCCTGCCTGATCGTGCGCAGCCGCCATCCGCTGCTGAAAAAGAAAAAGACCAGCA
GCCTTTCCGACATCCGGGATTACGACTGGGTGTTCCAGCCGCCGGGCACGCTGCTGCGCCGGACGATCGAGGATATTTTC
CTGTCGCGCGGCGTGGCGCTGCCGGAAAATATCGTCAACACCTCGTCGCTGCTTCTGACCTGCGCCATCGTCTGCGGAAC
CGACGCGATCGCGCCCGTTGCCACCGACGTTGCCCAGTTTCTCTCCAGCCAGAGCGCCAGGGCTTCCGACGTGCGCATGC
TGCCGATCGATTTCGACATCAACGTCAAGCCTTACAGCCTGATCACCGCCAGGGAACGGGCGCTGCCGCCGAGCGCAAGG
CTGCTCTATGACATCATTCTGGAGGAGAGCCAGAAGCAGGCGGGCTGA

Upstream 100 bases:

>100_bases
CTATAACTGTCAAATAGAATAAGTGGTAAAGTGCATAACAATTTTGGTATATCGTTAAAAAGTATTACTTTTGATGGAGC
GCAGCGAGGAGGCTGCAACC

Downstream 100 bases:

>100_bases
CGCGGCCCGCAAGCCCGGCGCCATCTTGCCCGTCTCTAATGCGCGCCGGAGCAATTCCAGCAAAGGGCGCAGCGGTTTTT
GCGTCCGGGAATTGCGTAAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTIVSEPISMDHVDIHSDSFGNDNLLRAGLKLNHLRMIVAIEDSGQISAAAEVLNISQPAASRMLSEMESITKTQLYERV
ARGVVLTTFGAALARRARKILLELREASREIGELKSGKGGSVFIGAVTAPAMSLVVPAINRVRKAYPGIEINIQVETSNV
LARELLAARHDFIISRIPDDLNPRLFEVTEIGIERACLIVRSRHPLLKKKKTSSLSDIRDYDWVFQPPGTLLRRTIEDIF
LSRGVALPENIVNTSSLLLTCAIVCGTDAIAPVATDVAQFLSSQSARASDVRMLPIDFDINVKPYSLITARERALPPSAR
LLYDIILEESQKQAG

Sequences:

>Translated_335_residues
MTIVSEPISMDHVDIHSDSFGNDNLLRAGLKLNHLRMIVAIEDSGQISAAAEVLNISQPAASRMLSEMESITKTQLYERV
ARGVVLTTFGAALARRARKILLELREASREIGELKSGKGGSVFIGAVTAPAMSLVVPAINRVRKAYPGIEINIQVETSNV
LARELLAARHDFIISRIPDDLNPRLFEVTEIGIERACLIVRSRHPLLKKKKTSSLSDIRDYDWVFQPPGTLLRRTIEDIF
LSRGVALPENIVNTSSLLLTCAIVCGTDAIAPVATDVAQFLSSQSARASDVRMLPIDFDINVKPYSLITARERALPPSAR
LLYDIILEESQKQAG
>Mature_334_residues
TIVSEPISMDHVDIHSDSFGNDNLLRAGLKLNHLRMIVAIEDSGQISAAAEVLNISQPAASRMLSEMESITKTQLYERVA
RGVVLTTFGAALARRARKILLELREASREIGELKSGKGGSVFIGAVTAPAMSLVVPAINRVRKAYPGIEINIQVETSNVL
ARELLAARHDFIISRIPDDLNPRLFEVTEIGIERACLIVRSRHPLLKKKKTSSLSDIRDYDWVFQPPGTLLRRTIEDIFL
SRGVALPENIVNTSSLLLTCAIVCGTDAIAPVATDVAQFLSSQSARASDVRMLPIDFDINVKPYSLITARERALPPSARL
LYDIILEESQKQAG

Specific function: Activator of the expression of chvE when bound to its inducer and represses its expression in the absence of inducer (L- arabinose, D-fucose or D-galactose). Negatively regulates its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081904, Length=306, Percent_Identity=24.1830065359477, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787601, Length=294, Percent_Identity=23.8095238095238, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI145693105, Length=180, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788297, Length=146, Percent_Identity=32.1917808219178, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789506, Length=301, Percent_Identity=21.5946843853821, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367136, Length=256, Percent_Identity=25.78125, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36775; Mature: 36644

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIVSEPISMDHVDIHSDSFGNDNLLRAGLKLNHLRMIVAIEDSGQISAAAEVLNISQPA
CCEECCCCCCCEEEECCCCCCCCCHHHHCCEEEEEEEEEEECCCCCHHHHHHHHHCCCHH
ASRMLSEMESITKTQLYERVARGVVLTTFGAALARRARKILLELREASREIGELKSGKGG
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SVFIGAVTAPAMSLVVPAINRVRKAYPGIEINIQVETSNVLARELLAARHDFIISRIPDD
EEEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCC
LNPRLFEVTEIGIERACLIVRSRHPLLKKKKTSSLSDIRDYDWVFQPPGTLLRRTIEDIF
CCCCEEHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHCCCCEECCCHHHHHHHHHHHH
LSRGVALPENIVNTSSLLLTCAIVCGTDAIAPVATDVAQFLSSQSARASDVRMLPIDFDI
HHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEC
NVKPYSLITARERALPPSARLLYDIILEESQKQAG
CCCCCCEEEHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TIVSEPISMDHVDIHSDSFGNDNLLRAGLKLNHLRMIVAIEDSGQISAAAEVLNISQPA
CEECCCCCCCEEEECCCCCCCCCHHHHCCEEEEEEEEEEECCCCCHHHHHHHHHCCCHH
ASRMLSEMESITKTQLYERVARGVVLTTFGAALARRARKILLELREASREIGELKSGKGG
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SVFIGAVTAPAMSLVVPAINRVRKAYPGIEINIQVETSNVLARELLAARHDFIISRIPDD
EEEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCC
LNPRLFEVTEIGIERACLIVRSRHPLLKKKKTSSLSDIRDYDWVFQPPGTLLRRTIEDIF
CCCCEEHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHCCCCEECCCHHHHHHHHHHHH
LSRGVALPENIVNTSSLLLTCAIVCGTDAIAPVATDVAQFLSSQSARASDVRMLPIDFDI
HHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEC
NVKPYSLITARERALPPSARLLYDIILEESQKQAG
CCCCCCEEEHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8253677; 2156804 [H]