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The map label for this gene is ycbL [H]

Identifier: 209550332

GI number: 209550332

Start: 2798131

End: 2798784

Strand: Direct

Name: ycbL [H]

Synonym: Rleg2_2753

Alternate gene names: 209550332

Gene position: 2798131-2798784 (Clockwise)

Preceding gene: 209550326

Following gene: 209550337

Centisome position: 61.66

GC content: 62.08

Gene sequence:

>654_bases
ATGGGCATGCTCCAGGCCGGCGTCATTCCGGTGACACCCTTCCAGCAGAACTGCACGATCTTCTTCGATCCCGAGACCAA
GGAAGGCGTCGTCGTCGATCCCGGCGGCGACGTGCCGCTGATCCTGCAGGCGATCGCGCAAAACGGCTTGATCATCAAGG
AAATTTGGCTGACACACGGCCATCTCGACCATGCCGGCGGCGCCAGCGAGCTGAAGGAAGCCTTGGGCATTGACGTGGTC
GGCCCGCATCAGGACGACCTGCCGCTGCTGCAGCGGATCGAGACCCAGGCCGAAAAATACGGCATATCGGGATTGCGCAA
CGTCCTGCCTGACCGCTGGCTGAAGGATGGCGACAAAATCTCCTTCGGCGACCACGAGTTCGAGGTCTATCATGCGCCCG
GTCATGCGCCGGGCCACGTCATCTATTTCAACCGGGCGCAGAATTTCGCCCATCTCGGCGACGTGCTCTTCAACGGCTCG
ATCGGCCGCACCGACCTGCCGGGCGGCAATCATCAGCAGCTTCTCGATTCGATCCGCGACAAGGTGCTGCCGCTCGGCGA
CGACGTCGGCTTCATCTGTGGCCATGGCCCCGGCAGCCGCATCGGCGATGAACGGCGCAGCAATCCATTTTTGCAGGAAA
TCAGAACCGGCTGA

Upstream 100 bases:

>100_bases
TTTTGACGTGAGGCAAGGCGGCAGACACGGAAAATTCCGGCTGTCCTTGACGCGGTTTCGGACTATACCCTGAGCATCCG
AGACACCAAGCGAGGCACTT

Downstream 100 bases:

>100_bases
GCGTTCGGCGCGGGCTCACATCATCTTCCGGCCGTTCGGCACGGGCTGCTCGACATCAGCAAGCACGATCGCGCCGCTCT
CGTCCTCGAATCCCAGCGTC

Product: beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MGMLQAGVIPVTPFQQNCTIFFDPETKEGVVVDPGGDVPLILQAIAQNGLIIKEIWLTHGHLDHAGGASELKEALGIDVV
GPHQDDLPLLQRIETQAEKYGISGLRNVLPDRWLKDGDKISFGDHEFEVYHAPGHAPGHVIYFNRAQNFAHLGDVLFNGS
IGRTDLPGGNHQQLLDSIRDKVLPLGDDVGFICGHGPGSRIGDERRSNPFLQEIRTG

Sequences:

>Translated_217_residues
MGMLQAGVIPVTPFQQNCTIFFDPETKEGVVVDPGGDVPLILQAIAQNGLIIKEIWLTHGHLDHAGGASELKEALGIDVV
GPHQDDLPLLQRIETQAEKYGISGLRNVLPDRWLKDGDKISFGDHEFEVYHAPGHAPGHVIYFNRAQNFAHLGDVLFNGS
IGRTDLPGGNHQQLLDSIRDKVLPLGDDVGFICGHGPGSRIGDERRSNPFLQEIRTG
>Mature_216_residues
GMLQAGVIPVTPFQQNCTIFFDPETKEGVVVDPGGDVPLILQAIAQNGLIIKEIWLTHGHLDHAGGASELKEALGIDVVG
PHQDDLPLLQRIETQAEKYGISGLRNVLPDRWLKDGDKISFGDHEFEVYHAPGHAPGHVIYFNRAQNFAHLGDVLFNGSI
GRTDLPGGNHQQLLDSIRDKVLPLGDDVGFICGHGPGSRIGDERRSNPFLQEIRTG

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=209, Percent_Identity=29.1866028708134, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1787158, Length=206, Percent_Identity=48.5436893203884, Blast_Score=210, Evalue=6e-56,
Organism=Escherichia coli, GI1786406, Length=186, Percent_Identity=35.4838709677419, Blast_Score=70, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17538952, Length=202, Percent_Identity=25.7425742574257, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI221330176, Length=205, Percent_Identity=23.9024390243902, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23645; Mature: 23514

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMLQAGVIPVTPFQQNCTIFFDPETKEGVVVDPGGDVPLILQAIAQNGLIIKEIWLTHG
CCCCCCCCEECCCCCCCCEEEECCCCCCCEEECCCCCHHHHHHHHHHCCEEEEEEHHHCC
HLDHAGGASELKEALGIDVVGPHQDDLPLLQRIETQAEKYGISGLRNVLPDRWLKDGDKI
CCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEE
SFGDHEFEVYHAPGHAPGHVIYFNRAQNFAHLGDVLFNGSIGRTDLPGGNHQQLLDSIRD
ECCCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
KVLPLGDDVGFICGHGPGSRIGDERRSNPFLQEIRTG
HCCCCCCCCCEEECCCCCCCCCCHHCCCHHHHHHCCC
>Mature Secondary Structure 
GMLQAGVIPVTPFQQNCTIFFDPETKEGVVVDPGGDVPLILQAIAQNGLIIKEIWLTHG
CCCCCCCEECCCCCCCCEEEECCCCCCCEEECCCCCHHHHHHHHHHCCEEEEEEHHHCC
HLDHAGGASELKEALGIDVVGPHQDDLPLLQRIETQAEKYGISGLRNVLPDRWLKDGDKI
CCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEE
SFGDHEFEVYHAPGHAPGHVIYFNRAQNFAHLGDVLFNGSIGRTDLPGGNHQQLLDSIRD
ECCCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
KVLPLGDDVGFICGHGPGSRIGDERRSNPFLQEIRTG
HCCCCCCCCCEEECCCCCCCCCCHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]