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The map label for this gene is chaA [C]

Identifier: 209550311

GI number: 209550311

Start: 2777702

End: 2778799

Strand: Direct

Name: chaA [C]

Synonym: Rleg2_2731

Alternate gene names: 209550311

Gene position: 2777702-2778799 (Clockwise)

Preceding gene: 209550309

Following gene: 209550317

Centisome position: 61.21

GC content: 61.75

Gene sequence:

>1098_bases
TTGGCGATTGCATCACGCTTAAAAGAAGAGAAGTTTCTGGTCGCCGCACTTGCCGTTGCAGCCATCGCCTATCTCTTGGA
ACACGCGGTGATCGAGATGGGACGCGGCGTCGCGCTGATCGCCGCCGCCGCCTTGGTCGGCACCATCGTTCTCGCCTCGA
TCCGCGTTGCCCATCACGCCGAACTGCTCGCCGTCAAGGTCGGCGACCCCTATGGCACGATGATCCTGACGCTGGCGGCT
GTTGCCGTGGAGGTCATCATCCTCGCCATCATGATGAGCGGAGAGAGTTCGCCGACACTGGTGCGCGACACGATTTATTC
CGCCCTGATGCTCGATATCAACGGCATTCTGGGTCTCGCCGCCCTGCTCGGCGGGCTGAAGCACGGCGAACAGCCCTACA
ACGACAATTCGGGCAAGACCTACGGCGTGATGATCCTCACCGCCATGGGCATCTCGATGATCGTGCCGGAATTCGTGCCC
GGCGACAAATGGCACTATTATTCCGCCTTCACCATCGTCGCGATGATTGCGCTCTACGGCCTCTTCCTGCGCATGCAGGT
CGGCCAGCACAGCTATTTTTTCAGCTACAGCTACCCGCGCTCCGAACGGAAGAAAGGGGCTTCGGACGCGCACGGCGCTG
ACGAGCCGGCAGCGATATCGATCGCCACAATTCTCGTCGGCGTCGTCATCATCGGCCTGCTGGCCGAGTTCATGTCGGCC
TTGATGACCGAGGGTCTGCGCGACAGCGGCGCGCCGATCGCCGTCACCGCCGTCGTCGTCGCGGCGATTTCAGCTGCCCC
CGAGATCCTGACCGCCTTGAAGGCGGCCCTCAAGAACCGCATGCAGGCGACCGTCAACATAGCCATGGGCGCCTCGCTCT
CGACCGTGATCCTGACGGTGCCGGTCATGGAGGCGATCGCGCTCTATACCGGCCAGCCCTTCATCATGGCGATGACCCCG
GTGCAGACGGTGATGGTGACGATCACGCTGATTGCCGCAGCGATCAACCTCAATGACGGCGAGACCAACGCCATCGAAGG
CATGACGCACTTCATCCTCTTTGCCACTTTCGTCATGCTGACGGCGCTGGGGCTTTGA

Upstream 100 bases:

>100_bases
TTAAACGCCGAAGACTGCAAATGGCACCAGACCGCGGCTTTCTTGATATGCGAAATCAGTGACTTAGATAAAACGCATGA
ATCGGGACAGGAGCTGAAAC

Downstream 100 bases:

>100_bases
AGACGGCGCTGCTTTCGATCTCGAAAGGAGTTCTCTCGGCAGGTCACGCCCGGCGGCGGGAGCCTGCGACAGTCATTCTT
TCGATTTTTCCAGGAAGCGC

Product: sodium/calcium exchanger membrane protein

Products: Na (I) [Periplasm]; Ca (II) [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MAIASRLKEEKFLVAALAVAAIAYLLEHAVIEMGRGVALIAAAALVGTIVLASIRVAHHAELLAVKVGDPYGTMILTLAA
VAVEVIILAIMMSGESSPTLVRDTIYSALMLDINGILGLAALLGGLKHGEQPYNDNSGKTYGVMILTAMGISMIVPEFVP
GDKWHYYSAFTIVAMIALYGLFLRMQVGQHSYFFSYSYPRSERKKGASDAHGADEPAAISIATILVGVVIIGLLAEFMSA
LMTEGLRDSGAPIAVTAVVVAAISAAPEILTALKAALKNRMQATVNIAMGASLSTVILTVPVMEAIALYTGQPFIMAMTP
VQTVMVTITLIAAAINLNDGETNAIEGMTHFILFATFVMLTALGL

Sequences:

>Translated_365_residues
MAIASRLKEEKFLVAALAVAAIAYLLEHAVIEMGRGVALIAAAALVGTIVLASIRVAHHAELLAVKVGDPYGTMILTLAA
VAVEVIILAIMMSGESSPTLVRDTIYSALMLDINGILGLAALLGGLKHGEQPYNDNSGKTYGVMILTAMGISMIVPEFVP
GDKWHYYSAFTIVAMIALYGLFLRMQVGQHSYFFSYSYPRSERKKGASDAHGADEPAAISIATILVGVVIIGLLAEFMSA
LMTEGLRDSGAPIAVTAVVVAAISAAPEILTALKAALKNRMQATVNIAMGASLSTVILTVPVMEAIALYTGQPFIMAMTP
VQTVMVTITLIAAAINLNDGETNAIEGMTHFILFATFVMLTALGL
>Mature_364_residues
AIASRLKEEKFLVAALAVAAIAYLLEHAVIEMGRGVALIAAAALVGTIVLASIRVAHHAELLAVKVGDPYGTMILTLAAV
AVEVIILAIMMSGESSPTLVRDTIYSALMLDINGILGLAALLGGLKHGEQPYNDNSGKTYGVMILTAMGISMIVPEFVPG
DKWHYYSAFTIVAMIALYGLFLRMQVGQHSYFFSYSYPRSERKKGASDAHGADEPAAISIATILVGVVIIGLLAEFMSAL
MTEGLRDSGAPIAVTAVVVAAISAAPEILTALKAALKNRMQATVNIAMGASLSTVILTVPVMEAIALYTGQPFIMAMTPV
QTVMVTITLIAAAINLNDGETNAIEGMTHFILFATFVMLTALGL

Specific function: Possible cation transporter [H]

COG id: COG0387

COG function: function code P; Ca2+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1787468, Length=366, Percent_Identity=33.0601092896175, Blast_Score=160, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6320075, Length=315, Percent_Identity=23.4920634920635, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004713
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 38343; Mature: 38212

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIASRLKEEKFLVAALAVAAIAYLLEHAVIEMGRGVALIAAAALVGTIVLASIRVAHHA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ELLAVKVGDPYGTMILTLAAVAVEVIILAIMMSGESSPTLVRDTIYSALMLDINGILGLA
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ALLGGLKHGEQPYNDNSGKTYGVMILTAMGISMIVPEFVPGDKWHYYSAFTIVAMIALYG
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LFLRMQVGQHSYFFSYSYPRSERKKGASDAHGADEPAAISIATILVGVVIIGLLAEFMSA
HHHHHHCCCCEEEEEECCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LMTEGLRDSGAPIAVTAVVVAAISAAPEILTALKAALKNRMQATVNIAMGASLSTVILTV
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHH
PVMEAIALYTGQPFIMAMTPVQTVMVTITLIAAAINLNDGETNAIEGMTHFILFATFVML
HHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
TALGL
HHHCC
>Mature Secondary Structure 
AIASRLKEEKFLVAALAVAAIAYLLEHAVIEMGRGVALIAAAALVGTIVLASIRVAHHA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ELLAVKVGDPYGTMILTLAAVAVEVIILAIMMSGESSPTLVRDTIYSALMLDINGILGLA
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ALLGGLKHGEQPYNDNSGKTYGVMILTAMGISMIVPEFVPGDKWHYYSAFTIVAMIALYG
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LFLRMQVGQHSYFFSYSYPRSERKKGASDAHGADEPAAISIATILVGVVIIGLLAEFMSA
HHHHHHCCCCEEEEEECCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LMTEGLRDSGAPIAVTAVVVAAISAAPEILTALKAALKNRMQATVNIAMGASLSTVILTV
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHH
PVMEAIALYTGQPFIMAMTPVQTVMVTITLIAAAINLNDGETNAIEGMTHFILFATFVML
HHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
TALGL
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Cytoplasm]; Proton [Periplasm]; Ca (II) [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: Na (I) [Cytoplasm] + Proton [Periplasm] = Proton [Cytoplasm] + Na (I) [Periplasm] Ca (II) [Cytoplasm] + Proton [Periplasm] = Ca (II) [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]