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The map label for this gene is ycgM [C]

Identifier: 209549960

GI number: 209549960

Start: 2438610

End: 2439305

Strand: Direct

Name: ycgM [C]

Synonym: Rleg2_2376

Alternate gene names: 209549960

Gene position: 2438610-2439305 (Clockwise)

Preceding gene: 209549958

Following gene: 209549961

Centisome position: 53.74

GC content: 63.36

Gene sequence:

>696_bases
ATGCCCCACCCCGTCACCGTCATCCCGCGTCCCGCACCGGTTCTGCTGCCGGTGGACGGCAGCGATGAGCGATTTCCGGT
GCGCCGCGTCTATTGCGTCGGGCGCAACTATGCCGACCATGCGATCGAGATGGGCCATGATCCCTCCCGCGAGCCGCCCT
TCTTCTTCCAGAAGAATGCCGATAACCTGCTGCCGGCAGACAAAGCTTTTCCTTATCCGCCGCTCTCGAACGATGTGCAT
TACGAGGTCGAATGCGTTCTGGCGCTGAAATCCGGCGGCGCTGACATTCAGGCGGCAGACGCGCTCGACTGCATTTACGG
CTATGCAGTCGGCATCGATTTCACCCGTCGAGACCTGCAGGGCGAGGCAAAGAAGCTCGGCCGCCCCTGGGAGGTCGGCA
AGGCCTTCGAGCATTCCGCCCCTGTCTCGCCGATCGTTCCGGCAAGCCGCATCGGCCACCCCTCGCAGGCAAGGATCTGG
CTGGAACAGAACGGCAGCCGAGTCCAGGATGGCGATCTCAACCAGATGATCTGGAAGGTGCCAGAAATCATCGCCGAGCT
GTCGAAGCTCTTCACCCTGGCGCCGGGCGATATCATCATGACCGGCACGCCCGCCGGCGTCGGCGCCGTTTCCAGGGGCG
ACCGCATCAGTTGCGGTATCGACGGCGTTGCCACCCTATCGGTCGAGGTCGTCTGA

Upstream 100 bases:

>100_bases
CGCCCGGCGGCGGGAGCGTCAATGCACCGAGAATGCTTCCCCGGCGCGTTGTTTTCCGTCTAAGATGGCGCCAAGACTCG
TCAAACAGGAAGAGCCGCCC

Downstream 100 bases:

>100_bases
GGAGAGAGCCATGCCCGTCTACGCGCTCGGCGGATCGACGCCGAAACTGCCCGCCGCCGGCCTCTATTGGATCGCACCAG
ACGCCAATATCATCGGCCAG

Product: fumarylacetoacetate hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MPHPVTVIPRPAPVLLPVDGSDERFPVRRVYCVGRNYADHAIEMGHDPSREPPFFFQKNADNLLPADKAFPYPPLSNDVH
YEVECVLALKSGGADIQAADALDCIYGYAVGIDFTRRDLQGEAKKLGRPWEVGKAFEHSAPVSPIVPASRIGHPSQARIW
LEQNGSRVQDGDLNQMIWKVPEIIAELSKLFTLAPGDIIMTGTPAGVGAVSRGDRISCGIDGVATLSVEVV

Sequences:

>Translated_231_residues
MPHPVTVIPRPAPVLLPVDGSDERFPVRRVYCVGRNYADHAIEMGHDPSREPPFFFQKNADNLLPADKAFPYPPLSNDVH
YEVECVLALKSGGADIQAADALDCIYGYAVGIDFTRRDLQGEAKKLGRPWEVGKAFEHSAPVSPIVPASRIGHPSQARIW
LEQNGSRVQDGDLNQMIWKVPEIIAELSKLFTLAPGDIIMTGTPAGVGAVSRGDRISCGIDGVATLSVEVV
>Mature_230_residues
PHPVTVIPRPAPVLLPVDGSDERFPVRRVYCVGRNYADHAIEMGHDPSREPPFFFQKNADNLLPADKAFPYPPLSNDVHY
EVECVLALKSGGADIQAADALDCIYGYAVGIDFTRRDLQGEAKKLGRPWEVGKAFEHSAPVSPIVPASRIGHPSQARIWL
EQNGSRVQDGDLNQMIWKVPEIIAELSKLFTLAPGDIIMTGTPAGVGAVSRGDRISCGIDGVATLSVEVV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=203, Percent_Identity=39.4088669950739, Blast_Score=157, Evalue=5e-39,
Organism=Homo sapiens, GI215422413, Length=200, Percent_Identity=40, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI66348062, Length=196, Percent_Identity=40.3061224489796, Blast_Score=154, Evalue=8e-38,
Organism=Homo sapiens, GI156231349, Length=234, Percent_Identity=33.7606837606838, Blast_Score=128, Evalue=4e-30,
Organism=Homo sapiens, GI40786394, Length=211, Percent_Identity=33.175355450237, Blast_Score=123, Evalue=1e-28,
Organism=Escherichia coli, GI1787428, Length=201, Percent_Identity=41.2935323383085, Blast_Score=143, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI17557057, Length=192, Percent_Identity=36.4583333333333, Blast_Score=145, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6324161, Length=238, Percent_Identity=31.5126050420168, Blast_Score=124, Evalue=9e-30,
Organism=Drosophila melanogaster, GI28571789, Length=203, Percent_Identity=33.4975369458128, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28572127, Length=213, Percent_Identity=30.5164319248826, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24663695, Length=219, Percent_Identity=29.2237442922374, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 25062; Mature: 24931

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHPVTVIPRPAPVLLPVDGSDERFPVRRVYCVGRNYADHAIEMGHDPSREPPFFFQKNA
CCCCCEEECCCCCEEEECCCCCCCCCEEEEEEECCCCHHHHHCCCCCCCCCCCEEEECCC
DNLLPADKAFPYPPLSNDVHYEVECVLALKSGGADIQAADALDCIYGYAVGIDFTRRDLQ
CCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCEEHHHHHHHHHHHHCCCCHHHHHCC
GEAKKLGRPWEVGKAFEHSAPVSPIVPASRIGHPSQARIWLEQNGSRVQDGDLNQMIWKV
HHHHHCCCCCHHCHHHHCCCCCCCCCCHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHH
PEIIAELSKLFTLAPGDIIMTGTPAGVGAVSRGDRISCGIDGVATLSVEVV
HHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCEEEECCCCEEEEEEEEC
>Mature Secondary Structure 
PHPVTVIPRPAPVLLPVDGSDERFPVRRVYCVGRNYADHAIEMGHDPSREPPFFFQKNA
CCCCEEECCCCCEEEECCCCCCCCCEEEEEEECCCCHHHHHCCCCCCCCCCCEEEECCC
DNLLPADKAFPYPPLSNDVHYEVECVLALKSGGADIQAADALDCIYGYAVGIDFTRRDLQ
CCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCEEHHHHHHHHHHHHCCCCHHHHHCC
GEAKKLGRPWEVGKAFEHSAPVSPIVPASRIGHPSQARIWLEQNGSRVQDGDLNQMIWKV
HHHHHCCCCCHHCHHHHCCCCCCCCCCHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHH
PEIIAELSKLFTLAPGDIIMTGTPAGVGAVSRGDRISCGIDGVATLSVEVV
HHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCEEEECCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]