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The map label for this gene is xylR [H]

Identifier: 209549912

GI number: 209549912

Start: 2388276

End: 2389490

Strand: Direct

Name: xylR [H]

Synonym: Rleg2_2328

Alternate gene names: 209549912

Gene position: 2388276-2389490 (Clockwise)

Preceding gene: 209549905

Following gene: 209549913

Centisome position: 52.63

GC content: 68.4

Gene sequence:

>1215_bases
GTGAAGTTAAAAGGCGACCAGACCACGGCGAGAGCCATGAACCGACGCCTCATTCTCAACCTTCTCCGGCGCGAGGGGCC
GAGGAGCCGCGCCGATATCGCCGCCGTCATCGGCTTGAGCCCGGCCGCCGTCACCTTCGTCGTCACCGACCTCTTGGAGG
AAGGCATCGTCATCGAAGGCAAGACCGTGCCCGGCCTCACCGGCCGCCGGCCGATCCCGGTCGATATCAACTACGAACAC
GCGCTTGCCGTCGGCTTCAAGCTGATGGTGGATTCGGTCGAGTGCGTGGCGACCGACCTCGCCACCAACCCGGTCGCCGC
CATGCGGGTCAGCCTGGCCGGCCACGATCCGGATCAGGTCGCCGACCTGCTGGCGGCGACCGTCCCGGAACTGGTGAAGC
TCGCCGGCCGGCCGAACGCCAGGCTTGCCGGCATCGGCATTTCCATGCCCGGCGTCATCAACCACGAACAGACGGCTTGC
GTGCGCAGCTACCGCTTCGGCTGGAACAACGTCCCCCTCGCCGCGCTGGTCGCTGCCCGCGTCCACGTGCCGGTCTGGCT
GGAGGACGACACCAACGCCTATGCCATCGCCCAGCAGCTCTTCGGGCTTGGCCGCCAGCACCGCAACATGGCGGTGCTCG
CCGTCGGCGTCGGCATCAGCTGCGCGCTCGTCATCGACGGCAAGCTCTATCGCGGCGCCAATGGTGCGGCCGGCAAGTTC
GGTCATACGCTGTTCGAGGAAGGCGGCCGGCTCTGCGAATGCGGCAAACGCGGCTGCCTGATGGCCTATCACTCGGAAAT
GTCGATGCTGCGCCGCTGGCGGGAGGCAACCGGCCGCGGCGAGGAACTGGGCTTGCCCCAACTCTGCGAGGCGCTCGCAT
CCGGCGACGCCACCGCCCTCGCCCTCGTCGCAGAGTCCGGCCGCGGCATCGGCACCGCCCTTGCCAATCTCGTCAACATC
ACCGACCCCGAAGTCATCGTCGCCGGCGGCGAAGCCGTCTCCCTCGGCGACCCCTTCCTGACGCCGCTGCGCGAAGCCCT
CGCCGCCCGAACCTTCCGCACCGCCCCGCCGCTCTTGCCCGACTGGGAGGACAATTCCTGGGCCCGAGGCGCCGCCGCGC
TGGTCACCCAGAAGATCTTCGACTTCGAGTCCTCTGGCGGGGTGACGGATATTGCGACGCTGTCAGGGGTTAGAGGCTCG
ACGTCGGCGGCTTGA

Upstream 100 bases:

>100_bases
TTCCAGCGATAATCCGCTTGGCTGAGTTGATCGGCGGCCGAACTTATGCATAGATCTTTTCGGCCCGCAATAATTAATTT
ACAAAATTAAGGAATGCATC

Downstream 100 bases:

>100_bases
GCGGCGGGAGATAGGCCGGATTTGCCGGATAAGTCATTCCGTGCAAGCCCCCCTCTGCCCTGCCGGGCATCTCCCCCACA
GGTGGGGAGATCGGCTGGGC

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MKLKGDQTTARAMNRRLILNLLRREGPRSRADIAAVIGLSPAAVTFVVTDLLEEGIVIEGKTVPGLTGRRPIPVDINYEH
ALAVGFKLMVDSVECVATDLATNPVAAMRVSLAGHDPDQVADLLAATVPELVKLAGRPNARLAGIGISMPGVINHEQTAC
VRSYRFGWNNVPLAALVAARVHVPVWLEDDTNAYAIAQQLFGLGRQHRNMAVLAVGVGISCALVIDGKLYRGANGAAGKF
GHTLFEEGGRLCECGKRGCLMAYHSEMSMLRRWREATGRGEELGLPQLCEALASGDATALALVAESGRGIGTALANLVNI
TDPEVIVAGGEAVSLGDPFLTPLREALAARTFRTAPPLLPDWEDNSWARGAAALVTQKIFDFESSGGVTDIATLSGVRGS
TSAA

Sequences:

>Translated_404_residues
MKLKGDQTTARAMNRRLILNLLRREGPRSRADIAAVIGLSPAAVTFVVTDLLEEGIVIEGKTVPGLTGRRPIPVDINYEH
ALAVGFKLMVDSVECVATDLATNPVAAMRVSLAGHDPDQVADLLAATVPELVKLAGRPNARLAGIGISMPGVINHEQTAC
VRSYRFGWNNVPLAALVAARVHVPVWLEDDTNAYAIAQQLFGLGRQHRNMAVLAVGVGISCALVIDGKLYRGANGAAGKF
GHTLFEEGGRLCECGKRGCLMAYHSEMSMLRRWREATGRGEELGLPQLCEALASGDATALALVAESGRGIGTALANLVNI
TDPEVIVAGGEAVSLGDPFLTPLREALAARTFRTAPPLLPDWEDNSWARGAAALVTQKIFDFESSGGVTDIATLSGVRGS
TSAA
>Mature_404_residues
MKLKGDQTTARAMNRRLILNLLRREGPRSRADIAAVIGLSPAAVTFVVTDLLEEGIVIEGKTVPGLTGRRPIPVDINYEH
ALAVGFKLMVDSVECVATDLATNPVAAMRVSLAGHDPDQVADLLAATVPELVKLAGRPNARLAGIGISMPGVINHEQTAC
VRSYRFGWNNVPLAALVAARVHVPVWLEDDTNAYAIAQQLFGLGRQHRNMAVLAVGVGISCALVIDGKLYRGANGAAGKF
GHTLFEEGGRLCECGKRGCLMAYHSEMSMLRRWREATGRGEELGLPQLCEALASGDATALALVAESGRGIGTALANLVNI
TDPEVIVAGGEAVSLGDPFLTPLREALAARTFRTAPPLLPDWEDNSWARGAAALVTQKIFDFESSGGVTDIATLSGVRGS
TSAA

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=267, Percent_Identity=25.0936329588015, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI4885285, Length=267, Percent_Identity=25.0936329588015, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI298566315, Length=267, Percent_Identity=25.0936329588015, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI190014632, Length=267, Percent_Identity=25.0936329588015, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1786891, Length=388, Percent_Identity=24.4845360824742, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787878, Length=332, Percent_Identity=26.2048192771084, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI87082127, Length=344, Percent_Identity=22.9651162790698, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081733, Length=310, Percent_Identity=24.8387096774194, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787363, Length=224, Percent_Identity=25.8928571428571, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 42616; Mature: 42616

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKGDQTTARAMNRRLILNLLRREGPRSRADIAAVIGLSPAAVTFVVTDLLEEGIVIEG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHCEEHEECCCHHHHHHHHHHHHHCCEEEEC
KTVPGLTGRRPIPVDINYEHALAVGFKLMVDSVECVATDLATNPVAAMRVSLAGHDPDQV
CCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCHHHH
ADLLAATVPELVKLAGRPNARLAGIGISMPGVINHEQTACVRSYRFGWNNVPLAALVAAR
HHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
VHVPVWLEDDTNAYAIAQQLFGLGRQHRNMAVLAVGVGISCALVIDGKLYRGANGAAGKF
HEEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEEECCEEEECCCCCCCHH
GHTLFEEGGRLCECGKRGCLMAYHSEMSMLRRWREATGRGEELGLPQLCEALASGDATAL
HHHHHHCCCCEEHHCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEE
ALVAESGRGIGTALANLVNITDPEVIVAGGEAVSLGDPFLTPLREALAARTFRTAPPLLP
EEEECCCCCHHHHHHHHHCCCCCCEEEECCCEEECCCHHHHHHHHHHHHHHHCCCCCCCC
DWEDNSWARGAAALVTQKIFDFESSGGVTDIATLSGVRGSTSAA
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKLKGDQTTARAMNRRLILNLLRREGPRSRADIAAVIGLSPAAVTFVVTDLLEEGIVIEG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHCEEHEECCCHHHHHHHHHHHHHCCEEEEC
KTVPGLTGRRPIPVDINYEHALAVGFKLMVDSVECVATDLATNPVAAMRVSLAGHDPDQV
CCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCHHHH
ADLLAATVPELVKLAGRPNARLAGIGISMPGVINHEQTACVRSYRFGWNNVPLAALVAAR
HHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
VHVPVWLEDDTNAYAIAQQLFGLGRQHRNMAVLAVGVGISCALVIDGKLYRGANGAAGKF
HEEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEEECCEEEECCCCCCCHH
GHTLFEEGGRLCECGKRGCLMAYHSEMSMLRRWREATGRGEELGLPQLCEALASGDATAL
HHHHHHCCCCEEHHCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEE
ALVAESGRGIGTALANLVNITDPEVIVAGGEAVSLGDPFLTPLREALAARTFRTAPPLLP
EEEECCCCCHHHHHHHHHCCCCCCEEEECCCEEECCCHHHHHHHHHHHHHHHCCCCCCCC
DWEDNSWARGAAALVTQKIFDFESSGGVTDIATLSGVRGSTSAA
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]