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The map label for this gene is sdaA [H]

Identifier: 209549456

GI number: 209549456

Start: 1909069

End: 1910472

Strand: Reverse

Name: sdaA [H]

Synonym: Rleg2_1862

Alternate gene names: 209549456

Gene position: 1910472-1909069 (Counterclockwise)

Preceding gene: 209549459

Following gene: 209549455

Centisome position: 42.1

GC content: 65.53

Gene sequence:

>1404_bases
ATGTTTCTCTCGGTATTCGATGTCTTCAAGATCGGTGTCGGGCCGTCGAGCTCGCACACGATGGGTCCGATGTCGGCCGC
CAACCGGTTTCTCGCGCTGATCCTGTCGAACGAATGGCCGCGCCCGTCCTCGGGCGCGCAGGTCGTGGCGATCACGGTCA
GCCTACACGGTTCGCTTGCGCATACCGGCATCGGCCACGGCACGGGCAGGGCCGTCATTCTCGGGCTGATGGGCGAGGCG
CCCGACAGCGTCGATCCCGACAAGATGGACGGTATCGTCGATACGGTGGAGCGCACCGGCCGCATCACGCCGGAGGGGCA
TCCCGGCTATCAGTTCCAGCCGAAGACCGACCTGATCTTCGACAAGAAACAGCCGCTGCCCGGCCATGCCAACGGCATGA
TCTTTTCCGCTTTTGACCGGGACGGCCGGCTGCTCGTCAAGCGCGTCTATTATTCGGTCGGCGGCGGTTTCGTCGTCACC
GACACCGAGCTGGAACAGATGCGGGCGAAGAAGAATGCGGCCGGCGGCACACGCGTGCCCTATCCCTTCGCGACCGCCAG
GCAGATGCTCGACATGGCCGAGCGCTCCGGGTTGTCGATCGCGCAGATGAAGCGGGCGAACGAGGAGAGCCAGCGCAGCC
CGGAGGAGCTCGATCAGGGGCTCGACCGCATCTGGGAGGCGATGCGTTCCTGTATCGAGCGCGGCCTCAAGGTCGAAGGC
ATCATGCCTGGTGGTCTCAACGTCAAGCGCCGCGCCCGCCGGATTCACGACAAGCTGGAGGAGGAGTGGCGCAGCAACCG
CGTCAACCCGCTGCTCGCCAACGACTGGCTGAGCGTCTACGCGATGGCCGTCAACGAGGAGAATGCCGCCGGCGGGCGCG
TCGTTACGGCGCCGACCAACGGGGCTGCCGGCGTCATTCCGGCGACGATCCGCTATTACGAGCATTTCCACGAGGACTGG
GATCAGAACGGCATCCGCGATTACCTGCTGACGGCCGCGGCTATCGGCGGCATCATAAAGCACAATGCCTCGATCTCCGG
CGCCGAGGTCGGCTGTCAGGGCGAGGTCGGCTCGGCGGCCGCGATGGCGGCCGCCGGCCTTGCCGCCGTCATGGGCGGCA
CGCCGGAGCAGATCGAGAACGCCGCCGAGATCGCGCTCGAACATCATCTCGGCATGACCTGCGATCCGGTCGCGGGTCTG
GTGCAGGTTCCCTGCATCGAGCGCAACGCGCTCGGCGCGGTCAAGGCGGTCACGGCGGCATCGCTTGCGGTCAAGGGCGA
TGGCCAGCATTTCGTGCCGCTCGACGCCTGTATCGAGACGATGCGTCAGACCGGCAATGACATGAGCGAAAAATACAAGG
AAACGTCGACGGGCGGCCTTGCCGTCAACGTCGTCGAATGCTGA

Upstream 100 bases:

>100_bases
AGCCACAATGTCGCACCGGCTGCATGCGATGTCGGTGGTCCGCACGGACGGAAAACCGGCGTCGCTTAAGCTTGCATCCT
CGTAATCAGAAGGCACATCC

Downstream 100 bases:

>100_bases
GTTTGTGGACGCGTGCGTTAGCGCGGATCAGCGCTTCACGGAAGCGCTGATCCGCTCTAAGTTTTTGTTTTTACGCAATT
CCGGACGGAAAACCGCTTAA

Product: L-serine dehydratase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MFLSVFDVFKIGVGPSSSHTMGPMSAANRFLALILSNEWPRPSSGAQVVAITVSLHGSLAHTGIGHGTGRAVILGLMGEA
PDSVDPDKMDGIVDTVERTGRITPEGHPGYQFQPKTDLIFDKKQPLPGHANGMIFSAFDRDGRLLVKRVYYSVGGGFVVT
DTELEQMRAKKNAAGGTRVPYPFATARQMLDMAERSGLSIAQMKRANEESQRSPEELDQGLDRIWEAMRSCIERGLKVEG
IMPGGLNVKRRARRIHDKLEEEWRSNRVNPLLANDWLSVYAMAVNEENAAGGRVVTAPTNGAAGVIPATIRYYEHFHEDW
DQNGIRDYLLTAAAIGGIIKHNASISGAEVGCQGEVGSAAAMAAAGLAAVMGGTPEQIENAAEIALEHHLGMTCDPVAGL
VQVPCIERNALGAVKAVTAASLAVKGDGQHFVPLDACIETMRQTGNDMSEKYKETSTGGLAVNVVEC

Sequences:

>Translated_467_residues
MFLSVFDVFKIGVGPSSSHTMGPMSAANRFLALILSNEWPRPSSGAQVVAITVSLHGSLAHTGIGHGTGRAVILGLMGEA
PDSVDPDKMDGIVDTVERTGRITPEGHPGYQFQPKTDLIFDKKQPLPGHANGMIFSAFDRDGRLLVKRVYYSVGGGFVVT
DTELEQMRAKKNAAGGTRVPYPFATARQMLDMAERSGLSIAQMKRANEESQRSPEELDQGLDRIWEAMRSCIERGLKVEG
IMPGGLNVKRRARRIHDKLEEEWRSNRVNPLLANDWLSVYAMAVNEENAAGGRVVTAPTNGAAGVIPATIRYYEHFHEDW
DQNGIRDYLLTAAAIGGIIKHNASISGAEVGCQGEVGSAAAMAAAGLAAVMGGTPEQIENAAEIALEHHLGMTCDPVAGL
VQVPCIERNALGAVKAVTAASLAVKGDGQHFVPLDACIETMRQTGNDMSEKYKETSTGGLAVNVVEC
>Mature_467_residues
MFLSVFDVFKIGVGPSSSHTMGPMSAANRFLALILSNEWPRPSSGAQVVAITVSLHGSLAHTGIGHGTGRAVILGLMGEA
PDSVDPDKMDGIVDTVERTGRITPEGHPGYQFQPKTDLIFDKKQPLPGHANGMIFSAFDRDGRLLVKRVYYSVGGGFVVT
DTELEQMRAKKNAAGGTRVPYPFATARQMLDMAERSGLSIAQMKRANEESQRSPEELDQGLDRIWEAMRSCIERGLKVEG
IMPGGLNVKRRARRIHDKLEEEWRSNRVNPLLANDWLSVYAMAVNEENAAGGRVVTAPTNGAAGVIPATIRYYEHFHEDW
DQNGIRDYLLTAAAIGGIIKHNASISGAEVGCQGEVGSAAAMAAAGLAAVMGGTPEQIENAAEIALEHHLGMTCDPVAGL
VQVPCIERNALGAVKAVTAASLAVKGDGQHFVPLDACIETMRQTGNDMSEKYKETSTGGLAVNVVEC

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=466, Percent_Identity=49.3562231759657, Blast_Score=418, Evalue=1e-118,
Organism=Escherichia coli, GI1789161, Length=467, Percent_Identity=46.8950749464668, Blast_Score=415, Evalue=1e-117,
Organism=Escherichia coli, GI1788116, Length=465, Percent_Identity=46.0215053763441, Blast_Score=405, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49959; Mature: 49959

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLSVFDVFKIGVGPSSSHTMGPMSAANRFLALILSNEWPRPSSGAQVVAITVSLHGSLA
CEEEHHHHHHHCCCCCCCCCCCCHHHHHHHEEEEECCCCCCCCCCCEEEEEEEEECCCHH
HTGIGHGTGRAVILGLMGEAPDSVDPDKMDGIVDTVERTGRITPEGHPGYQFQPKTDLIF
HCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEE
DKKQPLPGHANGMIFSAFDRDGRLLVKRVYYSVGGGFVVTDTELEQMRAKKNAAGGTRVP
CCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHCCCCCCCCC
YPFATARQMLDMAERSGLSIAQMKRANEESQRSPEELDQGLDRIWEAMRSCIERGLKVEG
CCHHHHHHHHHHHHHCCCHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEE
IMPGGLNVKRRARRIHDKLEEEWRSNRVNPLLANDWLSVYAMAVNEENAAGGRVVTAPTN
ECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEEEEECCCCCCCCEEEECCCC
GAAGVIPATIRYYEHFHEDWDQNGIRDYLLTAAAIGGIIKHNASISGAEVGCQGEVGSAA
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
AMAAAGLAAVMGGTPEQIENAAEIALEHHLGMTCDPVAGLVQVPCIERNALGAVKAVTAA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHH
SLAVKGDGQHFVPLDACIETMRQTGNDMSEKYKETSTGGLAVNVVEC
HEEEECCCCEECCHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure
MFLSVFDVFKIGVGPSSSHTMGPMSAANRFLALILSNEWPRPSSGAQVVAITVSLHGSLA
CEEEHHHHHHHCCCCCCCCCCCCHHHHHHHEEEEECCCCCCCCCCCEEEEEEEEECCCHH
HTGIGHGTGRAVILGLMGEAPDSVDPDKMDGIVDTVERTGRITPEGHPGYQFQPKTDLIF
HCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEE
DKKQPLPGHANGMIFSAFDRDGRLLVKRVYYSVGGGFVVTDTELEQMRAKKNAAGGTRVP
CCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHCCCCCCCCC
YPFATARQMLDMAERSGLSIAQMKRANEESQRSPEELDQGLDRIWEAMRSCIERGLKVEG
CCHHHHHHHHHHHHHCCCHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEE
IMPGGLNVKRRARRIHDKLEEEWRSNRVNPLLANDWLSVYAMAVNEENAAGGRVVTAPTN
ECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEEEEECCCCCCCCEEEECCCC
GAAGVIPATIRYYEHFHEDWDQNGIRDYLLTAAAIGGIIKHNASISGAEVGCQGEVGSAA
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
AMAAAGLAAVMGGTPEQIENAAEIALEHHLGMTCDPVAGLVQVPCIERNALGAVKAVTAA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHH
SLAVKGDGQHFVPLDACIETMRQTGNDMSEKYKETSTGGLAVNVVEC
HEEEECCCCEECCHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]