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The map label for this gene is yabD [H]

Identifier: 209549395

GI number: 209549395

Start: 1849018

End: 1849800

Strand: Reverse

Name: yabD [H]

Synonym: Rleg2_1801

Alternate gene names: 209549395

Gene position: 1849800-1849018 (Counterclockwise)

Preceding gene: 209549396

Following gene: 209549394

Centisome position: 40.76

GC content: 62.07

Gene sequence:

>783_bases
GTGCTGATCGATACGCATTGCCATCTTGATTTCGCCGACTTCGAGGCGGAGCGCGACGAGATCGTTTCGCGCGCCCATCA
GGCGGGCGTCAAGCAAATGGTGACGATTTCGACGCGGGTGCGCAAGCTCGACCGGCTGCTTGCGATCACCGAGAAATATC
CTTCGGTGTTCTGCTCGGTCGGCACGCATCCGAACAATGCCGACGAAGAGCTGGATATCCAGACGGAAGATCTGGTGCGC
CTTGCGAACGCCCATGAGAAGGTGGTGGCGATCGGCGAGGCCGGCCTCGATTATTTCTACGATACGCAGAAGCCCGAGGA
CCAGCAGACCGGCTTTCGCCGCCATATCGCGGCGGCGCGCGCCACACAGCTGCCGCTCGTCATCCACAGCCGCAGCGCCG
ATGAGGACATGGCAACGATCCTGACCGAGGAAACGGGGAAGGGGGCTTTCCCCTTCATCCTCCATTGCTTTTCGGCAGGT
CCGGAACTGGCGCGAACGGGCGTCGAACTCGGCGGCTATGTTTCCTTTTCGGGCATCCTGACCTTCCCGAAATCGGAAGA
GCTGCGCGAGATCGCCAAGACGATCCCCCAAGATCGGCTGCTGGTGGAAACGGATGCGCCGTATCTGGCGCCGAAGCGCT
GGCGCGGCAAGCGCAACGAACCGTCCTATGTCGTCAACACCGCCGAGGTGCTCGCCGAGACGATCGGCCTCTCCTACGCG
GAGGTCGCACGGATGACGACGGAGAACGCATTGCGCCTGTTCACGAAGATGCCGAGGGTCTGA

Upstream 100 bases:

>100_bases
TTTGCTGCTCTTGGCGAATCCGGCCGTCTCCTTGCCGGAACGCCGCTCGAAGCGCCGACGCCGGTCTTCCCGCGCTACGT
GGCTCCGGAGGCTTGAGGCC

Downstream 100 bases:

>100_bases
GAGCGTGCTCTACCGGCGGCGCTTCACCATTCTCGGCTGTTCGTCGTCACCCGGCGTGCCGCGCATTACCGGCGACTGGG
GCGCCTGCAATCCCGCCAAT

Product: hydrolase, TatD family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MLIDTHCHLDFADFEAERDEIVSRAHQAGVKQMVTISTRVRKLDRLLAITEKYPSVFCSVGTHPNNADEELDIQTEDLVR
LANAHEKVVAIGEAGLDYFYDTQKPEDQQTGFRRHIAAARATQLPLVIHSRSADEDMATILTEETGKGAFPFILHCFSAG
PELARTGVELGGYVSFSGILTFPKSEELREIAKTIPQDRLLVETDAPYLAPKRWRGKRNEPSYVVNTAEVLAETIGLSYA
EVARMTTENALRLFTKMPRV

Sequences:

>Translated_260_residues
MLIDTHCHLDFADFEAERDEIVSRAHQAGVKQMVTISTRVRKLDRLLAITEKYPSVFCSVGTHPNNADEELDIQTEDLVR
LANAHEKVVAIGEAGLDYFYDTQKPEDQQTGFRRHIAAARATQLPLVIHSRSADEDMATILTEETGKGAFPFILHCFSAG
PELARTGVELGGYVSFSGILTFPKSEELREIAKTIPQDRLLVETDAPYLAPKRWRGKRNEPSYVVNTAEVLAETIGLSYA
EVARMTTENALRLFTKMPRV
>Mature_260_residues
MLIDTHCHLDFADFEAERDEIVSRAHQAGVKQMVTISTRVRKLDRLLAITEKYPSVFCSVGTHPNNADEELDIQTEDLVR
LANAHEKVVAIGEAGLDYFYDTQKPEDQQTGFRRHIAAARATQLPLVIHSRSADEDMATILTEETGKGAFPFILHCFSAG
PELARTGVELGGYVSFSGILTFPKSEELREIAKTIPQDRLLVETDAPYLAPKRWRGKRNEPSYVVNTAEVLAETIGLSYA
EVARMTTENALRLFTKMPRV

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=268, Percent_Identity=31.7164179104478, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI226061853, Length=276, Percent_Identity=32.2463768115942, Blast_Score=124, Evalue=8e-29,
Organism=Homo sapiens, GI110349734, Length=268, Percent_Identity=31.3432835820896, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI226061614, Length=261, Percent_Identity=31.0344827586207, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI14042943, Length=263, Percent_Identity=25.8555133079848, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI225903424, Length=234, Percent_Identity=30.7692307692308, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI226061595, Length=234, Percent_Identity=29.9145299145299, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI225903439, Length=226, Percent_Identity=27.4336283185841, Blast_Score=89, Evalue=3e-18,
Organism=Escherichia coli, GI1787342, Length=259, Percent_Identity=41.6988416988417, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI87082439, Length=259, Percent_Identity=31.6602316602317, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI48994985, Length=260, Percent_Identity=31.5384615384615, Blast_Score=128, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17559024, Length=282, Percent_Identity=30.1418439716312, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71980746, Length=262, Percent_Identity=30.9160305343511, Blast_Score=123, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17565396, Length=214, Percent_Identity=33.1775700934579, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17543026, Length=191, Percent_Identity=32.9842931937173, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24648690, Length=284, Percent_Identity=31.3380281690141, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI221330018, Length=273, Percent_Identity=26.3736263736264, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24586117, Length=273, Percent_Identity=26.3736263736264, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29076; Mature: 29076

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDTHCHLDFADFEAERDEIVSRAHQAGVKQMVTISTRVRKLDRLLAITEKYPSVFCSV
CEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEC
GTHPNNADEELDIQTEDLVRLANAHEKVVAIGEAGLDYFYDTQKPEDQQTGFRRHIAAAR
CCCCCCCCCCCCCCHHHHHHHHCCHHHEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHH
ATQLPLVIHSRSADEDMATILTEETGKGAFPFILHCFSAGPELARTGVELGGYVSFSGIL
HHCCCEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHCHHHCCEEEECEEE
TFPKSEELREIAKTIPQDRLLVETDAPYLAPKRWRGKRNEPSYVVNTAEVLAETIGLSYA
ECCCCHHHHHHHHHCCCCCEEEECCCCCCCCHHHCCCCCCCCEEEHHHHHHHHHHCCCHH
EVARMTTENALRLFTKMPRV
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLIDTHCHLDFADFEAERDEIVSRAHQAGVKQMVTISTRVRKLDRLLAITEKYPSVFCSV
CEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEC
GTHPNNADEELDIQTEDLVRLANAHEKVVAIGEAGLDYFYDTQKPEDQQTGFRRHIAAAR
CCCCCCCCCCCCCCHHHHHHHHCCHHHEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHH
ATQLPLVIHSRSADEDMATILTEETGKGAFPFILHCFSAGPELARTGVELGGYVSFSGIL
HHCCCEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHCHHHCCEEEECEEE
TFPKSEELREIAKTIPQDRLLVETDAPYLAPKRWRGKRNEPSYVVNTAEVLAETIGLSYA
ECCCCHHHHHHHHHCCCCCEEEECCCCCCCCHHHCCCCCCCCEEEHHHHHHHHHHCCCHH
EVARMTTENALRLFTKMPRV
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]