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The map label for this gene is hit [H]

Identifier: 209549173

GI number: 209549173

Start: 1599547

End: 1599972

Strand: Reverse

Name: hit [H]

Synonym: Rleg2_1574

Alternate gene names: 209549173

Gene position: 1599972-1599547 (Counterclockwise)

Preceding gene: 209549174

Following gene: 209549165

Centisome position: 35.26

GC content: 61.97

Gene sequence:

>426_bases
ATGACCAGCGCCTATGACGACAACAACATCTTCGCCAAGATCCTGCGCGGCGAAATTCCCTCGCACCGTATCTACGAGGA
CCAGCATACCATCGCCTTCATGGATGTGATGCCGCAAGCGCCCGGCCATGTGCTCGTCGTGCCGAAGGCGGCGTCGCGCA
ATATTCTCGATGCCGATCCAGCCACCCTCACCCATGCGATTACCGTCGTCCAGAAGATTGCCAATGCGGTCAAGGAGGTC
TTCGACGCCGACGGCGTGTTCGTCGCCCAGTTCAACGAACCGGCCGCCGGGCAGACGGTGTTTCATCTGCATTTCCACAT
CATCCCGCGCCACGAGGGTGCCGCCCTCAAGCCGCACTCCGGCAAGATGGAGGATGGCGCCGTGCTTGCCGCCCATGCCG
AGAAGATCAGGGCGGCGCTGGCGTAA

Upstream 100 bases:

>100_bases
GCGAACACAGCCCCTTCCGCAAGGGCGAACGCCAGCAGGAGGATTGACGCCGCCCTGCCGGCGGCGTTACCCGAGCAAGA
GGAAATGAGGAGATTTCGCG

Downstream 100 bases:

>100_bases
GATCATTTGGCGAGTGTTGGCCGCGCCTTCATGCCGTTCAGCGGCAACAGAACCGCCAAAGCCGCCATGCTCAGCCCGCC
CAGAACCGCGAAAGTCGCCT

Product: histidine triad (HIT) protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MTSAYDDNNIFAKILRGEIPSHRIYEDQHTIAFMDVMPQAPGHVLVVPKAASRNILDADPATLTHAITVVQKIANAVKEV
FDADGVFVAQFNEPAAGQTVFHLHFHIIPRHEGAALKPHSGKMEDGAVLAAHAEKIRAALA

Sequences:

>Translated_141_residues
MTSAYDDNNIFAKILRGEIPSHRIYEDQHTIAFMDVMPQAPGHVLVVPKAASRNILDADPATLTHAITVVQKIANAVKEV
FDADGVFVAQFNEPAAGQTVFHLHFHIIPRHEGAALKPHSGKMEDGAVLAAHAEKIRAALA
>Mature_140_residues
TSAYDDNNIFAKILRGEIPSHRIYEDQHTIAFMDVMPQAPGHVLVVPKAASRNILDADPATLTHAITVVQKIANAVKEVF
DADGVFVAQFNEPAAGQTVFHLHFHIIPRHEGAALKPHSGKMEDGAVLAAHAEKIRAALA

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=105, Percent_Identity=37.1428571428571, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1787346, Length=105, Percent_Identity=36.1904761904762, Blast_Score=59, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17506713, Length=105, Percent_Identity=39.0476190476191, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320078, Length=107, Percent_Identity=37.3831775700935, Blast_Score=76, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320511, Length=103, Percent_Identity=34.9514563106796, Blast_Score=62, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28574010, Length=110, Percent_Identity=41.8181818181818, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24581222, Length=110, Percent_Identity=41.8181818181818, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 15277; Mature: 15145

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSAYDDNNIFAKILRGEIPSHRIYEDQHTIAFMDVMPQAPGHVLVVPKAASRNILDADP
CCCCCCCCCHHHHHHHCCCCCCCEECCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCC
ATLTHAITVVQKIANAVKEVFDADGVFVAQFNEPAAGQTVFHLHFHIIPRHEGAALKPHS
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEEEEEECCCCCEECCCC
GKMEDGAVLAAHAEKIRAALA
CCCCCCEEEEHHHHHHHHHCC
>Mature Secondary Structure 
TSAYDDNNIFAKILRGEIPSHRIYEDQHTIAFMDVMPQAPGHVLVVPKAASRNILDADP
CCCCCCCCHHHHHHHCCCCCCCEECCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCC
ATLTHAITVVQKIANAVKEVFDADGVFVAQFNEPAAGQTVFHLHFHIIPRHEGAALKPHS
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEEEEEECCCCCEECCCC
GKMEDGAVLAAHAEKIRAALA
CCCCCCEEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]