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The map label for this gene is kdgK [H]

Identifier: 209400541

GI number: 209400541

Start: 4524634

End: 4525563

Strand: Direct

Name: kdgK [H]

Synonym: ECH74115_4890

Alternate gene names: 209400541

Gene position: 4524634-4525563 (Clockwise)

Preceding gene: 209400488

Following gene: 209400592

Centisome position: 81.2

GC content: 56.56

Gene sequence:

>930_bases
ATGTCCAAAAAGATTGCCGTGATTGGCGAATGCATGATTGAGCTTTCCGAGAAAGGCGCGGACGTTAAGCGCGGTTTCGG
CGGCGATACCCTGAACACTTCCGTCTATATCGCCCGTCAGGTCGATCCTGCGGCATTAACCGTTCATTACGTAACGGCGC
TGGGAACGGACAGTTTTAGCCAGCAGATGCTGGACGCCTGGCACGGCGAGAACGTTGATACTTCCCTGACCCAACGGATG
GAAAACCGTCTGCCGGGCCTTTACTACATTGAAACCGACAGCACCGGCGAACGTACGTTCTACTACTGGCGTAACGAAGC
CGCCGCCAAATTCTGGCTGGAGAGCGATCAATCCGCGGCGATTTGCGAAGAGCTGGCGAATTTCGATTATCTCTACCTGA
GCGGGATTAGCCTGGCGATCTTAAGCCCGACCAGCCGCGAAAAGCTGCTTTCCCTGCTGCGCGAATGCCGCGCCAACGGC
GGAAAAGTGATTTTCGACAATAACTATCGTCCGCGCCTGTGGGCCAGCAAAGAAGAGACACAGCAGGTGTACCAACAAAT
GCTGGAATGCACGGATATCGCCTTCCTGACGCTGGACGATGAAGACGCGCTGTGGGGTCAACAGCCGGTGGAAGACGTCA
TTGCGCGCACCCATAACGCGGGCGTGAAAGAAGTGGTGGTGAAACGCGGGGCGGATTCTTGCCTGGTGTCCATTGCTGGC
GAAGGGTTAGTGGATGTTCCGGCGGTGAAACTGCCGAAAGAAAAAGTGATCGATACCACCGCAGCTGGCGACTCTTTCAG
TGCCGGTTATCTGGCGGTACGTTTGACGGGCGGCAGTGCGGAAAACGCAGCGAAACGCGGGCACCTGACCGCAAGTACCG
TTATTCAGTATCGCGGCGCGATTATCCCGCGTGAGGCGATGCCAGCGTAA

Upstream 100 bases:

>100_bases
CTGGCTCAAAAAAATAATGGAACACTGTTTTAATATGGTTGACCAGCAAACCACCACAGCGCAAACTAACGCTAATTTTT
TACAGATCAGGTTCACGACT

Downstream 100 bases:

>100_bases
ACGCAGCATATGCAAAAGGCTGGATAAAGAGTTACCCCTCTATCCAGCTCATCCATAAATACCTGATGGTTGTGCTAACT
CATCACCATCAGGCATTACT

Product: 2-dehydro-3-deoxygluconokinase

Products: NA

Alternate protein names: 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSKKIAVIGECMIELSEKGADVKRGFGGDTLNTSVYIARQVDPAALTVHYVTALGTDSFSQQMLDAWHGENVDTSLTQRM
ENRLPGLYYIETDSTGERTFYYWRNEAAAKFWLESDQSAAICEELANFDYLYLSGISLAILSPTSREKLLSLLRECRANG
GKVIFDNNYRPRLWASKEETQQVYQQMLECTDIAFLTLDDEDALWGQQPVEDVIARTHNAGVKEVVVKRGADSCLVSIAG
EGLVDVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLTGGSAENAAKRGHLTASTVIQYRGAIIPREAMPA

Sequences:

>Translated_309_residues
MSKKIAVIGECMIELSEKGADVKRGFGGDTLNTSVYIARQVDPAALTVHYVTALGTDSFSQQMLDAWHGENVDTSLTQRM
ENRLPGLYYIETDSTGERTFYYWRNEAAAKFWLESDQSAAICEELANFDYLYLSGISLAILSPTSREKLLSLLRECRANG
GKVIFDNNYRPRLWASKEETQQVYQQMLECTDIAFLTLDDEDALWGQQPVEDVIARTHNAGVKEVVVKRGADSCLVSIAG
EGLVDVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLTGGSAENAAKRGHLTASTVIQYRGAIIPREAMPA
>Mature_308_residues
SKKIAVIGECMIELSEKGADVKRGFGGDTLNTSVYIARQVDPAALTVHYVTALGTDSFSQQMLDAWHGENVDTSLTQRME
NRLPGLYYIETDSTGERTFYYWRNEAAAKFWLESDQSAAICEELANFDYLYLSGISLAILSPTSREKLLSLLRECRANGG
KVIFDNNYRPRLWASKEETQQVYQQMLECTDIAFLTLDDEDALWGQQPVEDVIARTHNAGVKEVVVKRGADSCLVSIAGE
GLVDVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLTGGSAENAAKRGHLTASTVIQYRGAIIPREAMPA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87082281, Length=309, Percent_Identity=99.3527508090615, Blast_Score=637, Evalue=0.0,
Organism=Escherichia coli, GI87081971, Length=276, Percent_Identity=27.8985507246377, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.45 [H]

Molecular weight: Translated: 33948; Mature: 33816

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKIAVIGECMIELSEKGADVKRGFGGDTLNTSVYIARQVDPAALTVHYVTALGTDSFS
CCCCHHHHHHHHHHHHHCCCCHHCCCCCCCCCCEEEEEEECCCHHEEEEEHHHHCCCHHH
QQMLDAWHGENVDTSLTQRMENRLPGLYYIETDSTGERTFYYWRNEAAAKFWLESDQSAA
HHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCEEEEECCCCHHH
ICEELANFDYLYLSGISLAILSPTSREKLLSLLRECRANGGKVIFDNNYRPRLWASKEET
HHHHHCCCCEEEECCCEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEECCHHHH
QQVYQQMLECTDIAFLTLDDEDALWGQQPVEDVIARTHNAGVKEVVVKRGADSCLVSIAG
HHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHHCCCCCEEEEECC
EGLVDVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLTGGSAENAAKRGHLTASTVIQYRGA
CCCEECCCCCCCHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHCCCCHHHHHHHHCCC
IIPREAMPA
CCCHHCCCC
>Mature Secondary Structure 
SKKIAVIGECMIELSEKGADVKRGFGGDTLNTSVYIARQVDPAALTVHYVTALGTDSFS
CCCHHHHHHHHHHHHHCCCCHHCCCCCCCCCCEEEEEEECCCHHEEEEEHHHHCCCHHH
QQMLDAWHGENVDTSLTQRMENRLPGLYYIETDSTGERTFYYWRNEAAAKFWLESDQSAA
HHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCEEEEECCCCHHH
ICEELANFDYLYLSGISLAILSPTSREKLLSLLRECRANGGKVIFDNNYRPRLWASKEET
HHHHHCCCCEEEECCCEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEECCHHHH
QQVYQQMLECTDIAFLTLDDEDALWGQQPVEDVIARTHNAGVKEVVVKRGADSCLVSIAG
HHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHHCCCCCEEEEECC
EGLVDVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLTGGSAENAAKRGHLTASTVIQYRGA
CCCEECCCCCCCHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHCCCCHHHHHHHHCCC
IIPREAMPA
CCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]