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The map label for this gene is mukE [H]

Identifier: 209400539

GI number: 209400539

Start: 1108593

End: 1109324

Strand: Direct

Name: mukE [H]

Synonym: ECH74115_1084

Alternate gene names: 209400539

Gene position: 1108593-1109324 (Clockwise)

Preceding gene: 209396953

Following gene: 209397222

Centisome position: 19.9

GC content: 51.64

Gene sequence:

>732_bases
ATGATTACGGAGCCAAGGTACAGGCGCATGTCATCGACAAATATTGAACAAGTGATGCCGGTTAAGCTGGCGCAGGCGCT
GGCGAATCCGTTATTTCCGGCGCTGGACAGCGCCTTACGTTCAGGCCGCCATATTGGCCTCGACGAACTGGATAATCATG
CATTCCTGATGGATTTTCAGGAATATCTGGAAGAGTTTTACGCGCGTTATAACGTTGAGCTTATTCGTGCACCGGAAGGG
TTCTTCTATTTACGTCCACGTTCCACCACGCTGATCCCTCGTTCCGTCTTGTCGGAACTGGATATGATGGTCGGGAAAAT
CCTCTGTTATCTCTATCTCAGCCCGGAACGGCTGGCGAATGAGGGGATTTTCACCCAGCAGGAACTGTACGACGAACTGC
TCACCCTGGCCGATGAAGCGAAACTGCTGAAACTGGTGAACAACCGTTCAACCGGTTCAGACATTGACCGTCAGAAGTTG
CAGGAAAAAGTACGTTCTTCGCTCAACCGTCTGCGTCGTTTAGGTATGGTGTGGTTTATGGGCCACGACAGCAGCAAGTT
CCGCATTACCGAATCGGTGTTCCGCTTCGGAGCCGATGTGCGTGCTGGCGACGATCCCCGTGAAGCACAGCGTCGCCTGA
TTCGTGATGGCGAAGCAATGCCGATTGAAAATCATCTGCAACTCAACGATGAAACCGAAGAGAATCAGCCAGATAGCGGA
GAGGAAGAATAA

Upstream 100 bases:

>100_bases
CGTCACTTTGACGTTGCGCGCATTGTTATTGATCAGGCGGTACGTCTTGGCGTAGCGCAAGCAGATTTCACCGGACTGCC
AGCGAAATGGCAGCCGATTA

Downstream 100 bases:

>100_bases
TGATTGAACGCGGTAAATTTCGCTCACTGACGCTGATTAACTGGAACGGCTTCTTTGCCCGAACTTTTGACCTTGACGAG
CTGGTCACGACGCTTTCTGG

Product: condesin subunit E

Products: NA

Alternate protein names: Protein kicA [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MITEPRYRRMSSTNIEQVMPVKLAQALANPLFPALDSALRSGRHIGLDELDNHAFLMDFQEYLEEFYARYNVELIRAPEG
FFYLRPRSTTLIPRSVLSELDMMVGKILCYLYLSPERLANEGIFTQQELYDELLTLADEAKLLKLVNNRSTGSDIDRQKL
QEKVRSSLNRLRRLGMVWFMGHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMPIENHLQLNDETEENQPDSG
EEE

Sequences:

>Translated_243_residues
MITEPRYRRMSSTNIEQVMPVKLAQALANPLFPALDSALRSGRHIGLDELDNHAFLMDFQEYLEEFYARYNVELIRAPEG
FFYLRPRSTTLIPRSVLSELDMMVGKILCYLYLSPERLANEGIFTQQELYDELLTLADEAKLLKLVNNRSTGSDIDRQKL
QEKVRSSLNRLRRLGMVWFMGHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMPIENHLQLNDETEENQPDSG
EEE
>Mature_243_residues
MITEPRYRRMSSTNIEQVMPVKLAQALANPLFPALDSALRSGRHIGLDELDNHAFLMDFQEYLEEFYARYNVELIRAPEG
FFYLRPRSTTLIPRSVLSELDMMVGKILCYLYLSPERLANEGIFTQQELYDELLTLADEAKLLKLVNNRSTGSDIDRQKL
QEKVRSSLNRLRRLGMVWFMGHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMPIENHLQLNDETEENQPDSG
EEE

Specific function: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interactio

COG id: COG3095

COG function: function code D; Uncharacterized protein involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm, nucleoid. Note=Restricted to the nucleoid region [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mukE family [H]

Homologues:

Organism=Escherichia coli, GI226510932, Length=234, Percent_Identity=99.5726495726496, Blast_Score=478, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007385 [H]

Pfam domain/function: PF04288 MukE [H]

EC number: NA

Molecular weight: Translated: 28192; Mature: 28192

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITEPRYRRMSSTNIEQVMPVKLAQALANPLFPALDSALRSGRHIGLDELDNHAFLMDFQ
CCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHCCCHHHHHHH
EYLEEFYARYNVELIRAPEGFFYLRPRSTTLIPRSVLSELDMMVGKILCYLYLSPERLAN
HHHHHHHHHHCCEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHC
EGIFTQQELYDELLTLADEAKLLKLVNNRSTGSDIDRQKLQEKVRSSLNRLRRLGMVWFM
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEE
GHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMPIENHLQLNDETEENQPDSG
CCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
EEE
CCC
>Mature Secondary Structure
MITEPRYRRMSSTNIEQVMPVKLAQALANPLFPALDSALRSGRHIGLDELDNHAFLMDFQ
CCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHCCCHHHHHHH
EYLEEFYARYNVELIRAPEGFFYLRPRSTTLIPRSVLSELDMMVGKILCYLYLSPERLAN
HHHHHHHHHHCCEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHC
EGIFTQQELYDELLTLADEAKLLKLVNNRSTGSDIDRQKLQEKVRSSLNRLRRLGMVWFM
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEE
GHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMPIENHLQLNDETEENQPDSG
CCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
EEE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7513784; 8905232; 9278503; 1989883; 8602138 [H]