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The map label for this gene is yjcS [H]

Identifier: 209400388

GI number: 209400388

Start: 5232498

End: 5234483

Strand: Reverse

Name: yjcS [H]

Synonym: ECH74115_5593

Alternate gene names: 209400388

Gene position: 5234483-5232498 (Counterclockwise)

Preceding gene: 209395750

Following gene: 209397725

Centisome position: 93.94

GC content: 52.57

Gene sequence:

>1986_bases
ATGAATAACTCTCGGTTATTCCGTTTGAGCAGGATTGTTATTGCGTTAACTGCCGCCAGCGGCATGATGGTAAATACCGC
TAACGCGAAAGAGGAAGCGAAAGCCGCCACTCAATATACCCAACAGGTTAATCAGAATTACGCCAAATCATTACCGTTTA
GCGATCGTCAGGATTTTGACGATGCCCAGCGTGGATTTATCGCCCCGCTGCTGGATGAAGGTATTCTGCGTGATGCGAAC
GGTAAAGTTTACTACCGCGCAGACGATTACAAATTTGATATTAATGCCGCTGCGCCGGAAACCGTAAACCCCAGCCTGTG
GCGTCAGTCGCAGATCAACGGCATTTCTGGCCTGTTCAAAGTCACCGATAAAATGTATCAGGTGCGCGGCCAGGATATCT
CTAACATTACGTTCGTTGAGGGGGAGAAAGGCATTATTGTCATCGACCCGCTGGTGACGCCGCCTGCCGCAAAAGCCGCA
CTTGACCTTTACTTCCAGCATCGTCCGCAAAAACCGATTGTTGCCGTTATCTACACTCACAGCCACACCGACCACTATGG
TGGCGTGAAAGGCATTATCTCTGAAGCCGATGTTAAATCCGGCAAAGTTCAGGTGATTGCCCCTGCTGGCTTTATGGACG
AAGCCATCAGCGAAAACGTGCTGGCGGGTAACATCATGAGCCGCCGTGCGCTCTACTCTTACGGTCTGTTACTGCCGCAC
AACGCGCAAGGCAACGTGGGTAATGGCCTTGGCGTGACGCTGGCAACGGGCGACCCGAGCATTATTGCACCGACTAAAAC
TATCGTCAGAACTGGCGAGAAGATGATTATCGACGGCCTGGAGTTTGACTTCCTGATGACCCCAGGTAGCGAAGCGCCAG
CCGAAATGCACTTCTATATTCCGGCCCTGAAAGCCCTGTGTACCGCCGAGAACGCCACGCATACCCTGCACAACTTCTAC
ACTCTGCGCGGCGCGAAAACCCGCGATACCAGCAAGTGGACCGAGTACCTGAACGAAACGCTGGATATGTGGGGTAACGA
CGCGGAAGTACTGTTTATGCCGCACACATGGCCGGTCTGGGGCAATAAGCATATCAATGATTATATTGGTAAATATCGCG
ATACTATCACGTTCATTCACGACCAGACCCTGCACCTGGCGAACCAGGGCTACACCATGAATGAAATCGGCGACATGATT
AAGCTGCCGCCTGCACTTGCCAATAACTGGGCCAGCCGTGGCTATTACGGTTCTGTCAGCCACAACGCCCGCGCGGTGTA
TAACTTCTATCTTGGCTATTACGACGGTAACCCGGCTAACCTGCATCCGTATGGTCAGGTAGAGATGGGCAAACGTTACG
TGAAAGCGCTGGGCGGCTCTGCCCGTGTCATCAACCTGGCGCAAGAAGCGAATAAGCAAGGTGATTACCGCTGGTCGGCA
GAACTACTGAAACAGGTGATTGCCGCCAACCCGGGTGACCAGGTGGCGAAGAATCTGCAAGCGAATAACTTTGAACAGCT
GGGCTATCAGGCCGAGTCCGCCACATGGCGCGGTTTCTACCTGACCGGCGCGAAAGAGCTGCGCGAAGGGGTGCATAAGT
TCAGCCACGGCACCACCGGTTCCCCGGACACCATTCGCGGAATGTCGGTCGAAATGCTGTTCGACTTTATGGCCGTTCGC
CTCGATAGCGCGAAAGCTGCGGGTAAAAATATCAGCCTGAACTTCAATATGAGCAACGGCGATAACCTCAACCTGACGCT
GAACGATAGCGTGCTTAACTACCGTAAAACACTGCAACCGCAAGCCGACGCCTCTTTCTACATCAGCCGTGAAGATCTGC
ACGCCGTGCTGACCGGACAGGCAAAAATGGCGGATCTGGTGAAAGCGAAGAAAGCCAAAATTATTGGCAATGGCGCGAAA
CTGGAAGAAATTATCGCCTGTCTGGATAATTTCGATTTGTGGGTGAATATCGTAACCCCAAATTAA

Upstream 100 bases:

>100_bases
TATTAAAGTCGCAATTTCCCAATTATGATAACGCCAGCTTTAAATGACGTATTTTGCATGGATTACATATTTACGACATA
AATGATAAATGGAGATTTAT

Downstream 100 bases:

>100_bases
TGTCACTCGCTTTTGGGGGCGCTGAAGCCCCCAAAAGCATTTATTTTAAAAATATATACAGCCAATTAATAAATAAAATA
TATAAGTTATGAATGCGGTG

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MNNSRLFRLSRIVIALTAASGMMVNTANAKEEAKAATQYTQQVNQNYAKSLPFSDRQDFDDAQRGFIAPLLDEGILRDAN
GKVYYRADDYKFDINAAAPETVNPSLWRQSQINGISGLFKVTDKMYQVRGQDISNITFVEGEKGIIVIDPLVTPPAAKAA
LDLYFQHRPQKPIVAVIYTHSHTDHYGGVKGIISEADVKSGKVQVIAPAGFMDEAISENVLAGNIMSRRALYSYGLLLPH
NAQGNVGNGLGVTLATGDPSIIAPTKTIVRTGEKMIIDGLEFDFLMTPGSEAPAEMHFYIPALKALCTAENATHTLHNFY
TLRGAKTRDTSKWTEYLNETLDMWGNDAEVLFMPHTWPVWGNKHINDYIGKYRDTITFIHDQTLHLANQGYTMNEIGDMI
KLPPALANNWASRGYYGSVSHNARAVYNFYLGYYDGNPANLHPYGQVEMGKRYVKALGGSARVINLAQEANKQGDYRWSA
ELLKQVIAANPGDQVAKNLQANNFEQLGYQAESATWRGFYLTGAKELREGVHKFSHGTTGSPDTIRGMSVEMLFDFMAVR
LDSAKAAGKNISLNFNMSNGDNLNLTLNDSVLNYRKTLQPQADASFYISREDLHAVLTGQAKMADLVKAKKAKIIGNGAK
LEEIIACLDNFDLWVNIVTPN

Sequences:

>Translated_661_residues
MNNSRLFRLSRIVIALTAASGMMVNTANAKEEAKAATQYTQQVNQNYAKSLPFSDRQDFDDAQRGFIAPLLDEGILRDAN
GKVYYRADDYKFDINAAAPETVNPSLWRQSQINGISGLFKVTDKMYQVRGQDISNITFVEGEKGIIVIDPLVTPPAAKAA
LDLYFQHRPQKPIVAVIYTHSHTDHYGGVKGIISEADVKSGKVQVIAPAGFMDEAISENVLAGNIMSRRALYSYGLLLPH
NAQGNVGNGLGVTLATGDPSIIAPTKTIVRTGEKMIIDGLEFDFLMTPGSEAPAEMHFYIPALKALCTAENATHTLHNFY
TLRGAKTRDTSKWTEYLNETLDMWGNDAEVLFMPHTWPVWGNKHINDYIGKYRDTITFIHDQTLHLANQGYTMNEIGDMI
KLPPALANNWASRGYYGSVSHNARAVYNFYLGYYDGNPANLHPYGQVEMGKRYVKALGGSARVINLAQEANKQGDYRWSA
ELLKQVIAANPGDQVAKNLQANNFEQLGYQAESATWRGFYLTGAKELREGVHKFSHGTTGSPDTIRGMSVEMLFDFMAVR
LDSAKAAGKNISLNFNMSNGDNLNLTLNDSVLNYRKTLQPQADASFYISREDLHAVLTGQAKMADLVKAKKAKIIGNGAK
LEEIIACLDNFDLWVNIVTPN
>Mature_661_residues
MNNSRLFRLSRIVIALTAASGMMVNTANAKEEAKAATQYTQQVNQNYAKSLPFSDRQDFDDAQRGFIAPLLDEGILRDAN
GKVYYRADDYKFDINAAAPETVNPSLWRQSQINGISGLFKVTDKMYQVRGQDISNITFVEGEKGIIVIDPLVTPPAAKAA
LDLYFQHRPQKPIVAVIYTHSHTDHYGGVKGIISEADVKSGKVQVIAPAGFMDEAISENVLAGNIMSRRALYSYGLLLPH
NAQGNVGNGLGVTLATGDPSIIAPTKTIVRTGEKMIIDGLEFDFLMTPGSEAPAEMHFYIPALKALCTAENATHTLHNFY
TLRGAKTRDTSKWTEYLNETLDMWGNDAEVLFMPHTWPVWGNKHINDYIGKYRDTITFIHDQTLHLANQGYTMNEIGDMI
KLPPALANNWASRGYYGSVSHNARAVYNFYLGYYDGNPANLHPYGQVEMGKRYVKALGGSARVINLAQEANKQGDYRWSA
ELLKQVIAANPGDQVAKNLQANNFEQLGYQAESATWRGFYLTGAKELREGVHKFSHGTTGSPDTIRGMSVEMLFDFMAVR
LDSAKAAGKNISLNFNMSNGDNLNLTLNDSVLNYRKTLQPQADASFYISREDLHAVLTGQAKMADLVKAKKAKIIGNGAK
LEEIIACLDNFDLWVNIVTPN

Specific function: Unknown

COG id: COG2015

COG function: function code Q; Alkyl sulfatase and related hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87082368, Length=661, Percent_Identity=99.5461422087746, Blast_Score=1369, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6324409, Length=637, Percent_Identity=45.3689167974882, Blast_Score=593, Evalue=1e-170,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR003033 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 73109; Mature: 73109

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNSRLFRLSRIVIALTAASGMMVNTANAKEEAKAATQYTQQVNQNYAKSLPFSDRQDFD
CCCCCEEHHEEEEEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
DAQRGFIAPLLDEGILRDANGKVYYRADDYKFDINAAAPETVNPSLWRQSQINGISGLFK
HHHCCCCCHHHCCCCEECCCCEEEEEECCEEEEECCCCCCCCCHHHHHHHHCCCHHHHHH
VTDKMYQVRGQDISNITFVEGEKGIIVIDPLVTPPAAKAALDLYFQHRPQKPIVAVIYTH
HHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEE
SHTDHYGGVKGIISEADVKSGKVQVIAPAGFMDEAISENVLAGNIMSRRALYSYGLLLPH
CCCCCCCCHHHHHCCCCCCCCCEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHCCEEEEC
NAQGNVGNGLGVTLATGDPSIIAPTKTIVRTGEKMIIDGLEFDFLMTPGSEAPAEMHFYI
CCCCCCCCCEEEEEECCCCCEECCCHHHHHCCCEEEEECCCEEEEECCCCCCCCEEEEHH
PALKALCTAENATHTLHNFYTLRGAKTRDTSKWTEYLNETLDMWGNDAEVLFMPHTWPVW
HHHHHHHHCCCCHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
GNKHINDYIGKYRDTITFIHDQTLHLANQGYTMNEIGDMIKLPPALANNWASRGYYGSVS
CCCCHHHHHHHHHHEEEEEECCEEEECCCCCCHHHHHHHHCCCHHHHCCCCCCCCCCCCC
HNARAVYNFYLGYYDGNPANLHPYGQVEMGKRYVKALGGSARVINLAQEANKQGDYRWSA
CCCEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEHHHCCCCCCCCHHH
ELLKQVIAANPGDQVAKNLQANNFEQLGYQAESATWRGFYLTGAKELREGVHKFSHGTTG
HHHHHHHCCCCHHHHHHHCCCCCHHHHCEECCCCEEEEEEEECHHHHHHHHHHHCCCCCC
SPDTIRGMSVEMLFDFMAVRLDSAKAAGKNISLNFNMSNGDNLNLTLNDSVLNYRKTLQP
CCCCCCCCHHHHHHHHHHHHHCCHHCCCCEEEEEEECCCCCEEEEEECCHHHHHHHHCCC
QADASFYISREDLHAVLTGQAKMADLVKAKKAKIIGNGAKLEEIIACLDNFDLWVNIVTP
CCCCEEEEEHHHHEEEEECCHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCEEEEEEECC
N
C
>Mature Secondary Structure
MNNSRLFRLSRIVIALTAASGMMVNTANAKEEAKAATQYTQQVNQNYAKSLPFSDRQDFD
CCCCCEEHHEEEEEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
DAQRGFIAPLLDEGILRDANGKVYYRADDYKFDINAAAPETVNPSLWRQSQINGISGLFK
HHHCCCCCHHHCCCCEECCCCEEEEEECCEEEEECCCCCCCCCHHHHHHHHCCCHHHHHH
VTDKMYQVRGQDISNITFVEGEKGIIVIDPLVTPPAAKAALDLYFQHRPQKPIVAVIYTH
HHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEE
SHTDHYGGVKGIISEADVKSGKVQVIAPAGFMDEAISENVLAGNIMSRRALYSYGLLLPH
CCCCCCCCHHHHHCCCCCCCCCEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHCCEEEEC
NAQGNVGNGLGVTLATGDPSIIAPTKTIVRTGEKMIIDGLEFDFLMTPGSEAPAEMHFYI
CCCCCCCCCEEEEEECCCCCEECCCHHHHHCCCEEEEECCCEEEEECCCCCCCCEEEEHH
PALKALCTAENATHTLHNFYTLRGAKTRDTSKWTEYLNETLDMWGNDAEVLFMPHTWPVW
HHHHHHHHCCCCHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
GNKHINDYIGKYRDTITFIHDQTLHLANQGYTMNEIGDMIKLPPALANNWASRGYYGSVS
CCCCHHHHHHHHHHEEEEEECCEEEECCCCCCHHHHHHHHCCCHHHHCCCCCCCCCCCCC
HNARAVYNFYLGYYDGNPANLHPYGQVEMGKRYVKALGGSARVINLAQEANKQGDYRWSA
CCCEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEHHHCCCCCCCCHHH
ELLKQVIAANPGDQVAKNLQANNFEQLGYQAESATWRGFYLTGAKELREGVHKFSHGTTG
HHHHHHHCCCCHHHHHHHCCCCCHHHHCEECCCCEEEEEEEECHHHHHHHHHHHCCCCCC
SPDTIRGMSVEMLFDFMAVRLDSAKAAGKNISLNFNMSNGDNLNLTLNDSVLNYRKTLQP
CCCCCCCCHHHHHHHHHHHHHCCHHCCCCEEEEEEECCCCCEEEEEECCHHHHHHHHCCC
QADASFYISREDLHAVLTGQAKMADLVKAKKAKIIGNGAKLEEIIACLDNFDLWVNIVTP
CCCCEEEEEHHHHEEEEECCHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCEEEEEEECC
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]