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The map label for this gene is stpA

Identifier: 209400130

GI number: 209400130

Start: 3624514

End: 3624918

Strand: Reverse

Name: stpA

Synonym: ECH74115_3911

Alternate gene names: 209400130

Gene position: 3624918-3624514 (Counterclockwise)

Preceding gene: 209398919

Following gene: 209397884

Centisome position: 65.06

GC content: 48.15

Gene sequence:

>405_bases
ATGTCCGTAATGTTACAAAGTTTAAATAACATTCGCACCCTCCGTGCGATGGCTCGCGAATTCTCCATTGACGTTCTTGA
AGAAATGCTCGAAAAATTCAGGGTTGTCACTAAAGAAAGACGTGAAGAAGAAGAACAGCAGCAGCGTGAACTGGCAGAGC
GCCAGGAAAAAATTAGCACCTGGCTGGAGCTGATGAAAGCTGACGGAATTAACCCGGAAGAGTTATTGGGTAATAGCTCT
GCTGCTGCACCACGTGCTGGTAAAAAACGCCAGCCGCGTCCGGCGAAATATAAATTCACCGATGTTAACGGTGAAACTAA
AACCTGGACCGGTCAGGGCCGTACACCGAAGCCAATCGCTCAGGCGCTGGCAGAAGGTAAATCTCTCGACGATTTCCTGA
TCTAA

Upstream 100 bases:

>100_bases
GACTGTAAATAGATTAAATTTTGTGGAAATATAATAAGTGATCGCTTACACTACGCGACGAAATACTTTTTTGTTTTGGC
GTTAAAAGGTTTTCTTTATT

Downstream 100 bases:

>100_bases
TTACTGAGGCCGGATGTCGCTGCTAGGGCGCGTCCGGCGTCGCTTCTCAAGCTCATTGGTTCCACGGCATCTTATCTAAC
AACCTTGCCATCCCACAAAA

Product: DNA binding protein, nucleoid-associated

Products: NA

Alternate protein names: H-NS homolog stpA

Number of amino acids: Translated: 134; Mature: 133

Protein sequence:

>134_residues
MSVMLQSLNNIRTLRAMAREFSIDVLEEMLEKFRVVTKERREEEEQQQRELAERQEKISTWLELMKADGINPEELLGNSS
AAAPRAGKKRQPRPAKYKFTDVNGETKTWTGQGRTPKPIAQALAEGKSLDDFLI

Sequences:

>Translated_134_residues
MSVMLQSLNNIRTLRAMAREFSIDVLEEMLEKFRVVTKERREEEEQQQRELAERQEKISTWLELMKADGINPEELLGNSS
AAAPRAGKKRQPRPAKYKFTDVNGETKTWTGQGRTPKPIAQALAEGKSLDDFLI
>Mature_133_residues
SVMLQSLNNIRTLRAMAREFSIDVLEEMLEKFRVVTKERREEEEQQQRELAERQEKISTWLELMKADGINPEELLGNSSA
AAPRAGKKRQPRPAKYKFTDVNGETKTWTGQGRTPKPIAQALAEGKSLDDFLI

Specific function: It may act in a fashion similar to H-NS proteins

COG id: COG2916

COG function: function code R; DNA-binding protein H-NS

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone-like protein H-NS family

Homologues:

Organism=Escherichia coli, GI1789023, Length=134, Percent_Identity=100, Blast_Score=271, Evalue=8e-75,
Organism=Escherichia coli, GI1787489, Length=135, Percent_Identity=57.7777777777778, Blast_Score=129, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): STPA_ECO57 (P0ACG2)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   B91070
- PIR:   E85914
- RefSeq:   NP_289219.1
- RefSeq:   NP_311557.1
- ProteinModelPortal:   P0ACG2
- EnsemblBacteria:   EBESCT00000024126
- EnsemblBacteria:   EBESCT00000058372
- GeneID:   914754
- GeneID:   958518
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z3968
- KEGG:   ecs:ECs3530
- GeneTree:   EBGT00050000008684
- HOGENOM:   HBG740436
- OMA:   NTWLELM
- ProtClustDB:   PRK10328
- BioCyc:   ECOL83334:ECS3530-MONOMER
- GO:   GO:0005622
- InterPro:   IPR001801
- SMART:   SM00528

Pfam domain/function: PF00816 Histone_HNS

EC number: NA

Molecular weight: Translated: 15348; Mature: 15217

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVMLQSLNNIRTLRAMAREFSIDVLEEMLEKFRVVTKERREEEEQQQRELAERQEKIST
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLELMKADGINPEELLGNSSAAAPRAGKKRQPRPAKYKFTDVNGETKTWTGQGRTPKPIA
HHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHH
QALAEGKSLDDFLI
HHHHCCCCCHHHCC
>Mature Secondary Structure 
SVMLQSLNNIRTLRAMAREFSIDVLEEMLEKFRVVTKERREEEEQQQRELAERQEKIST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLELMKADGINPEELLGNSSAAAPRAGKKRQPRPAKYKFTDVNGETKTWTGQGRTPKPIA
HHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHH
QALAEGKSLDDFLI
HHHHCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796