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The map label for this gene is wecD [H]

Identifier: 209400127

GI number: 209400127

Start: 4870969

End: 4871643

Strand: Direct

Name: wecD [H]

Synonym: ECH74115_5223

Alternate gene names: 209400127

Gene position: 4870969-4871643 (Clockwise)

Preceding gene: 209400406

Following gene: 209400869

Centisome position: 87.42

GC content: 55.26

Gene sequence:

>675_bases
GTGCCCGTCCGCGCCAGTATTGAGCCACTAACCTGGGAAAACGCCTTCTTTGGTGTTAACAGCGCCATCGTGCGCATTAC
GTCTGAAGCACCGTTCCTGACGCCAGACGCGTTAGCGCCGTGGTCACGGGTGCAGGCCAAAATTGCGGCATCAAATACGG
GGGAACTGGATGCCCTGCAACAGCTGGGATTCTCCCTGGTAGAAGGTGAAGTTGATTTGGCGCTACCCGTGAACAATGCC
AGTGATAGCGGTGCTGTAGTGGCACAAGAGACCGATATTCCCGCATTACGTCAGTTAGCCAGCGCCGCATTTGCGCAAAG
CCGTTTTCGTGCGCCGTGGTATGCGCCTGACGCCAGCAGTCGCTTTTATGCACAGTGGATTGAAAATGCCGTGCGCGGCA
CCTTTGATCATCAATGTCTGATTTTACGTGCGGCGTCCGGCGATATTCGCGGTTATGTCTCTTTACGGGAACTCAATGCT
ACAGATGCGCGAATTGGCCTGCTGGCTGGACGCGGTGCAGGTGCTGAGCTGATGCAAACGGCGCTAAACTGGGCGTATGC
TCGCGGTAAAACAACTTTGCGGGTGGCGACCCAAATGGGCAACACCGCCGCGCTTAAACGATACATACAAAGTGGTGCGA
ATGTAGAAAGCACCGCGTACTGGTTATACAGGTGA

Upstream 100 bases:

>100_bases
ATCGCCTGGCGTAACGGCTGGCTCGATGACGAGGGTGTGAAGCGTGCTGCCAGTTCATTAGCGAAAACTGGCTACGGCCA
ATATCTGCTGGAGTTACTTC

Downstream 100 bases:

>100_bases
TCACATGATTCCATTTAACGCACCGCCGGTGGTGGGAACCGAACTCGACTATATGCAGTCGGCAATGGGTAGCGGCAAAC
TGTGTGGCGATGGCGGTTTT

Product: TDP-fucosamine acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MPVRASIEPLTWENAFFGVNSAIVRITSEAPFLTPDALAPWSRVQAKIAASNTGELDALQQLGFSLVEGEVDLALPVNNA
SDSGAVVAQETDIPALRQLASAAFAQSRFRAPWYAPDASSRFYAQWIENAVRGTFDHQCLILRAASGDIRGYVSLRELNA
TDARIGLLAGRGAGAELMQTALNWAYARGKTTLRVATQMGNTAALKRYIQSGANVESTAYWLYR

Sequences:

>Translated_224_residues
MPVRASIEPLTWENAFFGVNSAIVRITSEAPFLTPDALAPWSRVQAKIAASNTGELDALQQLGFSLVEGEVDLALPVNNA
SDSGAVVAQETDIPALRQLASAAFAQSRFRAPWYAPDASSRFYAQWIENAVRGTFDHQCLILRAASGDIRGYVSLRELNA
TDARIGLLAGRGAGAELMQTALNWAYARGKTTLRVATQMGNTAALKRYIQSGANVESTAYWLYR
>Mature_223_residues
PVRASIEPLTWENAFFGVNSAIVRITSEAPFLTPDALAPWSRVQAKIAASNTGELDALQQLGFSLVEGEVDLALPVNNAS
DSGAVVAQETDIPALRQLASAAFAQSRFRAPWYAPDASSRFYAQWIENAVRGTFDHQCLILRAASGDIRGYVSLRELNAT
DARIGLLAGRGAGAELMQTALNWAYARGKTTLRVATQMGNTAALKRYIQSGANVESTAYWLYR

Specific function: Transaminase converting thymidine diphosphate(TDP)-4- keto-6-deoxy-D-glucose to TDP-4-amino-4,6-dideoxy-D-galactose, the immediate precursor of the ECA sugar TDP-Fuc4NAc [H]

COG id: COG0454

COG function: function code KR; Histone acetyltransferase HPA2 and related acetyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI145693203, Length=224, Percent_Identity=99.5535714285714, Blast_Score=450, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR012752
- InterPro:   IPR016181
- InterPro:   IPR002110
- InterPro:   IPR020683 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: NA

Molecular weight: Translated: 24255; Mature: 24123

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS50088 ANK_REPEAT ; PS50297 ANK_REP_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVRASIEPLTWENAFFGVNSAIVRITSEAPFLTPDALAPWSRVQAKIAASNTGELDALQ
CCCCCCCCCCEECCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHEEEECCCCCCHHHHH
QLGFSLVEGEVDLALPVNNASDSGAVVAQETDIPALRQLASAAFAQSRFRAPWYAPDASS
HCCHHEECCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
RFYAQWIENAVRGTFDHQCLILRAASGDIRGYVSLRELNATDARIGLLAGRGAGAELMQT
HHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEEECCCCCCEEEEEECCCCCHHHHHH
ALNWAYARGKTTLRVATQMGNTAALKRYIQSGANVESTAYWLYR
HHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCEEEEEC
>Mature Secondary Structure 
PVRASIEPLTWENAFFGVNSAIVRITSEAPFLTPDALAPWSRVQAKIAASNTGELDALQ
CCCCCCCCCEECCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHEEEECCCCCCHHHHH
QLGFSLVEGEVDLALPVNNASDSGAVVAQETDIPALRQLASAAFAQSRFRAPWYAPDASS
HCCHHEECCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
RFYAQWIENAVRGTFDHQCLILRAASGDIRGYVSLRELNATDARIGLLAGRGAGAELMQT
HHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEEECCCCCCEEEEEECCCCCHHHHHH
ALNWAYARGKTTLRVATQMGNTAALKRYIQSGANVESTAYWLYR
HHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503; 8366065 [H]