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The map label for this gene is ospG [H]

Identifier: 209399529

GI number: 209399529

Start: 2936108

End: 2936698

Strand: Reverse

Name: ospG [H]

Synonym: ECH74115_3181

Alternate gene names: 209399529

Gene position: 2936698-2936108 (Counterclockwise)

Preceding gene: 209398931

Following gene: 209397769

Centisome position: 52.7

GC content: 33.33

Gene sequence:

>591_bases
ATGAAAATAATATCCACTGTTATTCAAACACCTTTCCCATTTGAGAATAATAATTCTCATACTGGCGTAGTAACGGAGCC
TATTCTCGGTAAGTTAATAGGGCAAGGTTCAACAGCAGAAATCTTTGAAGATATGAATGATTCGTCTGCTTTATATAAAA
AGTATGATCTTGTTGGTAACCAGCACAATGAAGTTCTGGAAATGGCTAGGCAAGAATCTGCCCTTTTTAATACTTTTTAT
GGCGATGACGCATCAGTTGTTATACAGTATGGCGGTGATGTGTATCTCCGAATGCTACGCGTGCCAGGGATTCCCCTTAG
TGATATTGATACAGCTGATATTCCTGATAATCTAGAGAGCCTTTATCTGCAGTTGATATGTAAATTGAATGAGTTGAGTA
TAATCCATTACGATCTTAATACAGGTAATATGTTGTATGATAAAGAAAGTAATAGTTTATTTCCAATAGATTTTCGAAAT
ATTTATTCTGAATATTACTCTGCAACCAAAAATGATAAAGAGATTATCGATCGACGATTACAGATGCGTACAAATGATTT
TTATTCATTATTAAACAGAAAATATTTATAA

Upstream 100 bases:

>100_bases
AATAGCATATGTACTTACGTGGTTTCTGAGGTGGTAGCGCGTAATATTATTTTATGTAAAAATATCTTGTAATCTTTAAA
TTTCATAACAAGGGCATGTC

Downstream 100 bases:

>100_bases
GTGCTATATTCATGAATGAAAAATAGCTATATGCGTACATTCTCAACCTGCCCGTCACGTAGCAGGTTGAATCACTTTTT
CTTGATAAAGGGCTGGTCCT

Product: OspG

Products: NA

Alternate protein names: Effector protein OspG [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MKIISTVIQTPFPFENNNSHTGVVTEPILGKLIGQGSTAEIFEDMNDSSALYKKYDLVGNQHNEVLEMARQESALFNTFY
GDDASVVIQYGGDVYLRMLRVPGIPLSDIDTADIPDNLESLYLQLICKLNELSIIHYDLNTGNMLYDKESNSLFPIDFRN
IYSEYYSATKNDKEIIDRRLQMRTNDFYSLLNRKYL

Sequences:

>Translated_196_residues
MKIISTVIQTPFPFENNNSHTGVVTEPILGKLIGQGSTAEIFEDMNDSSALYKKYDLVGNQHNEVLEMARQESALFNTFY
GDDASVVIQYGGDVYLRMLRVPGIPLSDIDTADIPDNLESLYLQLICKLNELSIIHYDLNTGNMLYDKESNSLFPIDFRN
IYSEYYSATKNDKEIIDRRLQMRTNDFYSLLNRKYL
>Mature_196_residues
MKIISTVIQTPFPFENNNSHTGVVTEPILGKLIGQGSTAEIFEDMNDSSALYKKYDLVGNQHNEVLEMARQESALFNTFY
GDDASVVIQYGGDVYLRMLRVPGIPLSDIDTADIPDNLESLYLQLICKLNELSIIHYDLNTGNMLYDKESNSLFPIDFRN
IYSEYYSATKNDKEIIDRRLQMRTNDFYSLLNRKYL

Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is a kinase that is involved in down-regulation of the host innate response induced by invasive bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cell (By similarity). Note=Secreted via Mxi-Spa type III secretion system (TTSS), and delivered into the host cell (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 22506; Mature: 22506

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIISTVIQTPFPFENNNSHTGVVTEPILGKLIGQGSTAEIFEDMNDSSALYKKYDLVGN
CHHHHHHHCCCCCCCCCCCCCCEECHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHCCC
QHNEVLEMARQESALFNTFYGDDASVVIQYGGDVYLRMLRVPGIPLSDIDTADIPDNLES
CHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHEEHHHHCCCCCCCCCCCCCCCHHHHH
LYLQLICKLNELSIIHYDLNTGNMLYDKESNSLFPIDFRNIYSEYYSATKNDKEIIDRRL
HHHHHHHHHCCEEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHH
QMRTNDFYSLLNRKYL
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIISTVIQTPFPFENNNSHTGVVTEPILGKLIGQGSTAEIFEDMNDSSALYKKYDLVGN
CHHHHHHHCCCCCCCCCCCCCCEECHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHCCC
QHNEVLEMARQESALFNTFYGDDASVVIQYGGDVYLRMLRVPGIPLSDIDTADIPDNLES
CHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHEEHHHHCCCCCCCCCCCCCCCHHHHH
LYLQLICKLNELSIIHYDLNTGNMLYDKESNSLFPIDFRNIYSEYYSATKNDKEIIDRRL
HHHHHHHHHCCEEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHH
QMRTNDFYSLLNRKYL
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA