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The map label for this gene is stxB [H]

Identifier: 209399287

GI number: 209399287

Start: 2696202

End: 2696471

Strand: Reverse

Name: stxB [H]

Synonym: ECH74115_2905

Alternate gene names: 209399287

Gene position: 2696471-2696202 (Counterclockwise)

Preceding gene: 209397665

Following gene: 209398353

Centisome position: 48.39

GC content: 41.11

Gene sequence:

>270_bases
ATGAAGAAGATGTTTATGGCGGTTTTATTTGCATTAGTTTCTGTTAATGCAATGGCGGCGGATTGCGCTAAAGGTAAAAT
TGAGTTTTCCAAGTATAATGAGAATGATACATTCACAGTAAAAGTGGCCGGAAAAGAGTACTGGACCAGTCGCTGGAATC
TGCAACCGTTACTGCAAAGTGCTCAGTTGACAGGAATGACTGTCACAATCAAATCCAGTACCTGTGAATCAGGCTCCGGA
TTTGCTGAAGTGCAGTTTAATAATGACTGA

Upstream 100 bases:

>100_bases
TAAAAATAAACAATACATTATGGGAAAGTAATACAGCTGCAGCGTTTCTGAACAGAAAGTCACAGTTTTTATATACAACG
GGTAAATAAAGGAGTTAAGT

Downstream 100 bases:

>100_bases
GGCATAACCTGATTCGTGGTATGTGGGTAACAAGTGTAATCTGTGTCACAATTCAGTCAGTTGACAGTTGCCTGTCAGAC
TGAGCATTCGTTAAAAAAAT

Product: shigatoxin 2, subunit B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 89; Mature: 89

Protein sequence:

>89_residues
MKKMFMAVLFALVSVNAMAADCAKGKIEFSKYNENDTFTVKVAGKEYWTSRWNLQPLLQSAQLTGMTVTIKSSTCESGSG
FAEVQFNND

Sequences:

>Translated_89_residues
MKKMFMAVLFALVSVNAMAADCAKGKIEFSKYNENDTFTVKVAGKEYWTSRWNLQPLLQSAQLTGMTVTIKSSTCESGSG
FAEVQFNND
>Mature_89_residues
MKKMFMAVLFALVSVNAMAADCAKGKIEFSKYNENDTFTVKVAGKEYWTSRWNLQPLLQSAQLTGMTVTIKSSTCESGSG
FAEVQFNND

Specific function: The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the stxB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008992
- InterPro:   IPR003189
- ProDom:   PD006042 [H]

Pfam domain/function: PF02258 SLT_beta [H]

EC number: NA

Molecular weight: Translated: 9857; Mature: 9857

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKMFMAVLFALVSVNAMAADCAKGKIEFSKYNENDTFTVKVAGKEYWTSRWNLQPLLQS
CHHHHHHHHHHHHHCCHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHC
AQLTGMTVTIKSSTCESGSGFAEVQFNND
CCCCCEEEEEECCCCCCCCCEEEEEECCC
>Mature Secondary Structure
MKKMFMAVLFALVSVNAMAADCAKGKIEFSKYNENDTFTVKVAGKEYWTSRWNLQPLLQS
CHHHHHHHHHHHHHCCHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHC
AQLTGMTVTIKSSTCESGSGFAEVQFNND
CCCCCEEEEEECCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA