Click here to switch to the map view.

The map label for this gene is ygcU

Identifier: 209399257

GI number: 209399257

Start: 3722478

End: 3723932

Strand: Reverse

Name: ygcU

Synonym: ECH74115_4029

Alternate gene names: 209399257

Gene position: 3723932-3722478 (Counterclockwise)

Preceding gene: 209397522

Following gene: 209400482

Centisome position: 66.83

GC content: 50.93

Gene sequence:

>1455_bases
ATGTCTTTATCTCGCGCAGCGATTGTCGACCAGCTAAAGGAAATTGTTGGTGCAGATCGCGTAATTACCGATGAAACAGT
ATTAAAGAAGAACAGTATTGACCGTTTTCGTAAATTTCCGGATATTCATGGCATTTATACTTTGCCGATTCCGGCAGCGG
TCGTAAAACTCGGTTCCACAGAGCAAGTATCCCGTGTGCTGAATTTTATGAATGCGCACAAAATTAACGGTGTGCCGCGT
ACCGGTGCTTCCGCCACCGAAGGTGGGCTGGAAACTGTTGTAGAAAACTCGGTGGTGCTCGACGGTTCCGCCATGAATCA
AATCATTAATATTGATATTGAGAATATGCAGGCGACGGCGCAATGTGGTGTTCCGCTGGAGGTGCTGGAAAACGCGTTGC
GTGAAAAAGGTTACACCACGGGGCATTCTCCGCAGTCAAAGCCGCTGGCGCAGATGGGCGGCCTGGTAGCAACCCGCAGT
ATCGGGCAGTTCTCCACACTCTACGGCGCAATCGAAGATATGGTCGTTGGTCTGGAGGCAGTGTTGGCAGATGGCACCGT
CACACGCATTAAAAACGTGCCACGCCGCGCGGCTGGCCCGGACATTCGTCACATCATCATCGGCAACGAAGGTGCATTGT
GCTATATCACTGAAGTAACAGTGAAAATCTTTAAATTCACCCCGGAAAACAACCTCTTCTACGGCTATATCCTGGAAGAC
ATGAAAACCGGCTTCAACATCCTGCGTGAAATCATGGTGGAAGGGTATCGTCCGTCGATCGCTCGTTTGTATGACGCTGA
AGATGGCACCCAACACTTCACCCATTTTGCCGACGGAAAATGCGTGCTGATCTTTATGGCTGAAGGTAACCCTCGCATTG
CGAAGGCGACGGGCGAAGGGATTGCGGAAATCGTTGCCCGCTACCCGCAATGCCAACGCGTGGACAGCAAGCTGATCGAA
ACCTGGTTTAACAACCTGAACTGGGGACCGGATAAAGTGGCTGCCGAACGTGTGCAGATCCTCAAAACCGGCAACATGGG
CTTTACTACCGAAGTGTCCGGCTGCTGGAGCTGCATCCACGAAATCTACGAAAGCGTTATTAACCGTATTCGTACCGAGT
TCCCGCACGCCGACGACATCACCATGCTGGGCGGTCACTCCTCTCATAGCTATCAGAACGGCACCAACATGTACTTCGTC
TACGACTACAACGTTGTCAACTGTAAGCCGGAAGAGGAAATCGACAAGTACCACAATCCGCTCAACAAAATCATTTGCGA
AGAAACCATTCGCCTCGGTGGTTCGATGGTGCACCACCACGGTATCGGTAAACATCGCGTTCACTGGAGCAAGCTGGAAC
ACGGCAGCGCGTGGGCGTTGCTGGAAGGGCTGAAAAAGCAGTTCGATCCTAATGGCATTATGAATACGGGTACTATCTAT
CCGATTGAAAAATAA

Upstream 100 bases:

>100_bases
AGTGGTCGATGGCGGTTATTTAGTGCGCTAACCCATAACGGTGGTTTCTGTTTTCTCTTATTAATGATTATTCCATTTTT
ATTATCAGGAAGGAATTACT

Downstream 100 bases:

>100_bases
TGTGTCAGGCAGCGTTCCGCGATGATGGGGCGTTGCCTTTTCGGCTTCTCAGGCGAGAAGCCGTTCTTATTACCGGACAA
TGAAGGGGTAAAGATGAACA

Product: FAD binding domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPR
TGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRS
IGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILED
MKTGFNILREIMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIE
TWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFV
YDYNVVNCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIY
PIEK

Sequences:

>Translated_484_residues
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPR
TGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRS
IGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILED
MKTGFNILREIMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIE
TWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFV
YDYNVVNCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIY
PIEK
>Mature_483_residues
SLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRT
GASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSI
GQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDM
KTGFNILREIMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIET
WFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVY
DYNVVNCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIYP
IEK

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain

Homologues:

Organism=Homo sapiens, GI4501993, Length=456, Percent_Identity=28.7280701754386, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI37595756, Length=220, Percent_Identity=27.7272727272727, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI119964728, Length=202, Percent_Identity=27.2277227722772, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI48994907, Length=484, Percent_Identity=99.5867768595041, Blast_Score=1004, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17556096, Length=462, Percent_Identity=27.7056277056277, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI71992373, Length=492, Percent_Identity=24.390243902439, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71992381, Length=489, Percent_Identity=23.721881390593, Blast_Score=82, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6320027, Length=175, Percent_Identity=32, Blast_Score=94, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6320023, Length=169, Percent_Identity=30.1775147928994, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320764, Length=179, Percent_Identity=27.3743016759777, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24653753, Length=486, Percent_Identity=25.7201646090535, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI18921117, Length=169, Percent_Identity=30.1775147928994, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24639277, Length=169, Percent_Identity=30.1775147928994, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24639275, Length=169, Percent_Identity=30.1775147928994, Blast_Score=78, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YGCU_ECO57 (Q8X7S0)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   E91082
- PIR:   F85927
- RefSeq:   NP_289323.1
- RefSeq:   NP_311656.1
- ProteinModelPortal:   Q8X7S0
- SMR:   Q8X7S0
- EnsemblBacteria:   EBESCT00000024726
- EnsemblBacteria:   EBESCT00000058391
- GeneID:   914648
- GeneID:   958231
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z4084
- KEGG:   ecs:ECs3629
- GeneTree:   EBGT00050000008853
- HOGENOM:   HBG416937
- OMA:   HACANGI
- ProtClustDB:   CLSK880487
- BioCyc:   ECOL83334:ECS3629-MONOMER
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR006094
- InterPro:   IPR016171
- Gene3D:   G3DSA:3.30.43.10
- Gene3D:   G3DSA:3.30.465.20
- Gene3D:   G3DSA:1.10.45.10

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4; SSF55103 FAD-binding_2; SSF56176 FAD-binding_2

EC number: NA

Molecular weight: Translated: 53709; Mature: 53578

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS51387 FAD_PCMH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGST
CCCHHHHHHHHHHHHHCCCCEECCHHHHHHCCHHHHHCCCCCCCEEECCHHHHHHHCCCH
EQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCEEECCHHHHHEEEEEECCCCHHH
QCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEA
HCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHH
VLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILED
HHCCCHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEEEEEEEEECCCCCEEEEEEHHH
MKTGFNILREIMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEG
HHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHEECCCCEEEEEEECCCCCEEECCCHH
IAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIH
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEECCCCCCCHHHHHHHHHH
EIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVNCKPEEEIDKYHNP
HHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHCH
LNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIY
HHHHHHHHHHHHCCHHHHHCCCCCCCEEHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEE
PIEK
ECCC
>Mature Secondary Structure 
SLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGST
CCHHHHHHHHHHHHHCCCCEECCHHHHHHCCHHHHHCCCCCCCEEECCHHHHHHHCCCH
EQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCEEECCHHHHHEEEEEECCCCHHH
QCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEA
HCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHH
VLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILED
HHCCCHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEEEEEEEEECCCCCEEEEEEHHH
MKTGFNILREIMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEG
HHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHEECCCCEEEEEEECCCCCEEECCCHH
IAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIH
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEECCCCCCCHHHHHHHHHH
EIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVNCKPEEEIDKYHNP
HHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHCH
LNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIY
HHHHHHHHHHHHCCHHHHHCCCCCCCEEHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEE
PIEK
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796