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The map label for this gene is ulaA

Identifier: 209399248

GI number: 209399248

Start: 5348907

End: 5350304

Strand: Direct

Name: ulaA

Synonym: ECH74115_5709

Alternate gene names: 209399248

Gene position: 5348907-5350304 (Clockwise)

Preceding gene: 209398637

Following gene: 209397475

Centisome position: 95.99

GC content: 53.0

Gene sequence:

>1398_bases
ATGGAGATCCTCTACAACATCTTTACCGTATTTTTTAACCAGGTCATGACCAATGCCCCGTTGTTGCTGGGTATTGTGAC
CTGTCTGGGCTACATCCTACTGCGCAAAAGTGTCAGCGTTATTATTAAAGGCACGATTAAAACCATAATTGGTTTCATGT
TGTTGCAGGCAGGGTCCGGCATCCTCACCAGCACCTTCAAACCGGTGGTGGCGAAAATGTCCGAAGTCTACGGCATTAAC
GGCGCAATTTCCGATACCTACGCTTCAATGATGGCAACCATCGACCGCATGGGCGATGCCTATAGCTGGGTGGGTTACGC
CGTATTGTTAGCGCTGGCACTGAACATCTGTTACGTGCTGTTGCGTCGCATTACCGGCATTCGCACAATCATGTTGACCG
GCCACATCATGTTCCAGCAGGCCGGGTTGATTGCCGTTACGCTGTTTATCTTCGGCTACTCCATGTGGACCACCATTATC
TGTACCGCGATTCTGGTTTCGCTCTACTGGGGCATCACTTCCAACATGATGTACAAGCCGACTCAGGAAGTGACGGATGG
CTGTGGTTTCTCCATCGGTCACCAGCAGCAGTTTGCATCATGGATTGCCTATAAAGTCGCGCCGTTCCTCGGCAAAAAAG
AGGAGAGCGTTGAAGACCTCAAACTGCCGGGCTGGCTGAACATTTTCCACGACAACATCGTCTCCACGGCGATTGTGATG
ACCATCTTCTTTGGCGCCATTCTGCTCTCCTTCGGTATCGACACCGTGCAGGCGATGGCGGGCAAAGTGCACTGGACGGT
CTACATCCTGCAAACCGGTTTCTCCTTCGCGGTGGCGATCTTCATCATCACTCAGGGCGTGCGCATGTTTGTGGCGGAAC
TCTCTGAAGCATTTAACGGTATCTCCCAGCGCCTGATCCCAGGTGCGGTTCTGGCGATTGACTGTGCGGCTATCTATAGC
TTCGCGCCGAACGCCGTGGTCTGGGGCTTTATGTGGGGCACCATCGGTCAGCTGATTGCAGTTGGCATCCTGGTCGCCTG
CGGCTCTTCCATTCTGATTATTCTAGGCTTTATCCCGATGTTCTTCTCCAACGCCACCATCGGCGTGTTCGCTAACCACT
TCGGCGGCTGGCGTGCAGCGCTGAAGATTTGTCTGGTGATGGGAATGATCGAAATCTTTGGTTGCGTCTGGGCGGTGAAA
CTCACCGGTATGAGTGCCTGGATGGGCATGGCGGACTGGTCGATTCTGGCACCGCCGATGATGCAAGGCTTCTTCTCCAT
CGGTATCGCCTTTATGGCCGTCATCATTGTAATTGCACTGGCTTATATGTTCTTCGCTGGCCGCGCGCTGCGCGCAGAAG
AAGATGCAGAAAAACAACTGGCAGAACAGTCTGCTTAA

Upstream 100 bases:

>100_bases
TCATAAATAATCTTGTTGTGATTACTTTTGAAAATTAGAGTGAGTGCACAACATTCCGGGTGTGTGGAATACCCGGTTAC
CTCTTCTTCAGGAGATCGTT

Downstream 100 bases:

>100_bases
TAAGGAGTTTTGATTATGACCGTACGTATTCTGGCTGTGTGTGGCAACGGACAAGGCAGTTCCATGATCATGAAGATGAA
AGTGGACCAGTTTTTAACCC

Product: PTS system ascorbate-specific transporter subunit IIC

Products: NA

Alternate protein names: Ascorbate-specific PTS system EIIC component

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MEILYNIFTVFFNQVMTNAPLLLGIVTCLGYILLRKSVSVIIKGTIKTIIGFMLLQAGSGILTSTFKPVVAKMSEVYGIN
GAISDTYASMMATIDRMGDAYSWVGYAVLLALALNICYVLLRRITGIRTIMLTGHIMFQQAGLIAVTLFIFGYSMWTTII
CTAILVSLYWGITSNMMYKPTQEVTDGCGFSIGHQQQFASWIAYKVAPFLGKKEESVEDLKLPGWLNIFHDNIVSTAIVM
TIFFGAILLSFGIDTVQAMAGKVHWTVYILQTGFSFAVAIFIITQGVRMFVAELSEAFNGISQRLIPGAVLAIDCAAIYS
FAPNAVVWGFMWGTIGQLIAVGILVACGSSILIILGFIPMFFSNATIGVFANHFGGWRAALKICLVMGMIEIFGCVWAVK
LTGMSAWMGMADWSILAPPMMQGFFSIGIAFMAVIIVIALAYMFFAGRALRAEEDAEKQLAEQSA

Sequences:

>Translated_465_residues
MEILYNIFTVFFNQVMTNAPLLLGIVTCLGYILLRKSVSVIIKGTIKTIIGFMLLQAGSGILTSTFKPVVAKMSEVYGIN
GAISDTYASMMATIDRMGDAYSWVGYAVLLALALNICYVLLRRITGIRTIMLTGHIMFQQAGLIAVTLFIFGYSMWTTII
CTAILVSLYWGITSNMMYKPTQEVTDGCGFSIGHQQQFASWIAYKVAPFLGKKEESVEDLKLPGWLNIFHDNIVSTAIVM
TIFFGAILLSFGIDTVQAMAGKVHWTVYILQTGFSFAVAIFIITQGVRMFVAELSEAFNGISQRLIPGAVLAIDCAAIYS
FAPNAVVWGFMWGTIGQLIAVGILVACGSSILIILGFIPMFFSNATIGVFANHFGGWRAALKICLVMGMIEIFGCVWAVK
LTGMSAWMGMADWSILAPPMMQGFFSIGIAFMAVIIVIALAYMFFAGRALRAEEDAEKQLAEQSA
>Mature_465_residues
MEILYNIFTVFFNQVMTNAPLLLGIVTCLGYILLRKSVSVIIKGTIKTIIGFMLLQAGSGILTSTFKPVVAKMSEVYGIN
GAISDTYASMMATIDRMGDAYSWVGYAVLLALALNICYVLLRRITGIRTIMLTGHIMFQQAGLIAVTLFIFGYSMWTTII
CTAILVSLYWGITSNMMYKPTQEVTDGCGFSIGHQQQFASWIAYKVAPFLGKKEESVEDLKLPGWLNIFHDNIVSTAIVM
TIFFGAILLSFGIDTVQAMAGKVHWTVYILQTGFSFAVAIFIITQGVRMFVAELSEAFNGISQRLIPGAVLAIDCAAIYS
FAPNAVVWGFMWGTIGQLIAVGILVACGSSILIILGFIPMFFSNATIGVFANHFGGWRAALKICLVMGMIEIFGCVWAVK
LTGMSAWMGMADWSILAPPMMQGFFSIGIAFMAVIIVIALAYMFFAGRALRAEEDAEKQLAEQSA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active- transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3037

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ulaA family

Homologues:

Organism=Escherichia coli, GI87082388, Length=465, Percent_Identity=99.7849462365591, Blast_Score=931, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ULAA_ECO57 (Q8XDJ5)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   A86116
- PIR:   A98275
- RefSeq:   NP_290823.2
- RefSeq:   NP_313196.2
- EnsemblBacteria:   EBESCT00000024646
- EnsemblBacteria:   EBESCT00000059905
- GeneID:   914004
- GeneID:   959930
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z5802
- KEGG:   ecs:ECs5169
- GeneTree:   EBGT00050000011076
- HOGENOM:   HBG296693
- OMA:   NAVTIGF
- ProtClustDB:   PRK09410
- BioCyc:   ECOL83334:ECS5169-MONOMER
- InterPro:   IPR004703

Pfam domain/function: PF03611 EIIC-GAT

EC number: NA

Molecular weight: Translated: 50754; Mature: 50754

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12032430)-; HASH(0x13b35d9c)-; HASH(0x133ff144)-; HASH(0x12617378)-; HASH(0x1206de34)-; HASH(0x10bbc0cc)-; HASH(0x13c74d48)-; HASH(0x139218c0)-; HASH(0x13b0cb70)-; HASH(0x104f1470)-;

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHCCH
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796