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The map label for this gene is sorM [H]

Identifier: 209398685

GI number: 209398685

Start: 5143320

End: 5144144

Strand: Reverse

Name: sorM [H]

Synonym: ECH74115_5494

Alternate gene names: 209398685

Gene position: 5144144-5143320 (Counterclockwise)

Preceding gene: 209398121

Following gene: 209399864

Centisome position: 92.32

GC content: 55.64

Gene sequence:

>825_bases
ATGGAACAGAGAAAAATTACACGCGGCGATCTGGTGAGCATGTTTCTGCGCTCCAACCTGCAACAGGCGTCCTTTAACTT
TGAACGTATTCACGGGCTGGGTTTTTGCTACGACATGATCCCCGCCATCAAGCGACTTTACCCAGTAAAAGAGGATCAGG
TTGCGGCGCTCAGGCGACACCTGGTGTTCTTTAATACCACGCCAGCCGTATGTGGCCCGGTCATCGGCGTCACTGCCGCC
ATGGAAGAGGCGCGGGCCAACGGCGCGGAAATTGATGACGGCACCATTAACGGCATCAAAGTCGGTCTGATGGGACCATT
GGCAGGGGTTGGCGATCCACTGGTCTGGGGAACGCTGCGCCCGATTACCGCCGCGCTCGGCGCATCGCTGGCGCTGTCTG
GCAACATTCTCGGCCCGCTGCTGTTCTTCTTTATTTTCAACGCGGTGCGTCTGGCGATGAAGTGGTATGGCCTACAGCTC
GGCTTTCGCAAAGGGGTGAATATCGTCAGCGATATGGGCGGGAATGTGCTGCAAAAACTCACCGAAGGCGCGTCGATTCT
CGGACTGTTTGTGATGGGCGTGCTGGTCACCAAATGGACGTCAATCAACGTACCGTTGGTGGTTTCACAAACGCATGCCG
CCGATGGCTCCACCGTCACCATGACCGTGCAGAACATTCTCGATCAACTTTGCCCTGGTTTGCTGGCGCTCGGTCTGACG
CTACTGATGGTTCGTCTGCTCAACAAAAAAATTAACCCGGTATGGCTGATTTTCGCCCTGTTTGGCTTAGGGATTATCGG
CAATGCGCTGGGCTTCCTGTCCTGA

Upstream 100 bases:

>100_bases
GTCTACATCCAGCTAAATCCACAGTGGCGTAAAGCTGAACCTCAACTCCTGGCCCCCGCTTCCACCGCCCTTGACCAACT
TGACGATTAACGGAGCCATC

Downstream 100 bases:

>100_bases
TTCTTCGCCCCGGCACGACTGCCGGGGCCATCGTTCAACATGAGGTGGTTTATGAAAACAACAGCTCTGCGTCTTTATGG
TAAACGTGATTTACGCCTGG

Product: PTS system, mannose/fructose/sorbose family, IID component

Products: protein histidine; sugar phosphate; D-glucosamine-6-phosphate [Cytoplasm]; pyruvate; glucose-6-phosphate [Cytoplasm]; N-acetyl-D-glucosamine-6-phosphate [Cytoplasm]; mannose-6-phosphate [Cytoplasm]; fructose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIID-Sor; PTS system sorbose-specific EIID component [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MEQRKITRGDLVSMFLRSNLQQASFNFERIHGLGFCYDMIPAIKRLYPVKEDQVAALRRHLVFFNTTPAVCGPVIGVTAA
MEEARANGAEIDDGTINGIKVGLMGPLAGVGDPLVWGTLRPITAALGASLALSGNILGPLLFFFIFNAVRLAMKWYGLQL
GFRKGVNIVSDMGGNVLQKLTEGASILGLFVMGVLVTKWTSINVPLVVSQTHAADGSTVTMTVQNILDQLCPGLLALGLT
LLMVRLLNKKINPVWLIFALFGLGIIGNALGFLS

Sequences:

>Translated_274_residues
MEQRKITRGDLVSMFLRSNLQQASFNFERIHGLGFCYDMIPAIKRLYPVKEDQVAALRRHLVFFNTTPAVCGPVIGVTAA
MEEARANGAEIDDGTINGIKVGLMGPLAGVGDPLVWGTLRPITAALGASLALSGNILGPLLFFFIFNAVRLAMKWYGLQL
GFRKGVNIVSDMGGNVLQKLTEGASILGLFVMGVLVTKWTSINVPLVVSQTHAADGSTVTMTVQNILDQLCPGLLALGLT
LLMVRLLNKKINPVWLIFALFGLGIIGNALGFLS
>Mature_274_residues
MEQRKITRGDLVSMFLRSNLQQASFNFERIHGLGFCYDMIPAIKRLYPVKEDQVAALRRHLVFFNTTPAVCGPVIGVTAA
MEEARANGAEIDDGTINGIKVGLMGPLAGVGDPLVWGTLRPITAALGASLALSGNILGPLLFFFIFNAVRLAMKWYGLQL
GFRKGVNIVSDMGGNVLQKLTEGASILGLFVMGVLVTKWTSINVPLVVSQTHAADGSTVTMTVQNILDQLCPGLLALGLT
LLMVRLLNKKINPVWLIFALFGLGIIGNALGFLS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3716

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIID domain [H]

Homologues:

Organism=Escherichia coli, GI1788122, Length=272, Percent_Identity=62.1323529411765, Blast_Score=345, Evalue=2e-96,
Organism=Escherichia coli, GI1789529, Length=274, Percent_Identity=36.8613138686131, Blast_Score=159, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004704
- InterPro:   IPR018405 [H]

Pfam domain/function: PF03613 EIID-AGA [H]

EC number: NA

Molecular weight: Translated: 29454; Mature: 29454

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS51108 PTS_EIID

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQRKITRGDLVSMFLRSNLQQASFNFERIHGLGFCYDMIPAIKRLYPVKEDQVAALRRH
CCCCCCHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LVFFNTTPAVCGPVIGVTAAMEEARANGAEIDDGTINGIKVGLMGPLAGVGDPLVWGTLR
HHEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHH
PITAALGASLALSGNILGPLLFFFIFNAVRLAMKWYGLQLGFRKGVNIVSDMGGNVLQKL
HHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHH
TEGASILGLFVMGVLVTKWTSINVPLVVSQTHAADGSTVTMTVQNILDQLCPGLLALGLT
HCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
LLMVRLLNKKINPVWLIFALFGLGIIGNALGFLS
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEQRKITRGDLVSMFLRSNLQQASFNFERIHGLGFCYDMIPAIKRLYPVKEDQVAALRRH
CCCCCCHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LVFFNTTPAVCGPVIGVTAAMEEARANGAEIDDGTINGIKVGLMGPLAGVGDPLVWGTLR
HHEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHH
PITAALGASLALSGNILGPLLFFFIFNAVRLAMKWYGLQLGFRKGVNIVSDMGGNVLQKL
HHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHH
TEGASILGLFVMGVLVTKWTSINVPLVVSQTHAADGSTVTMTVQNILDQLCPGLLALGLT
HCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
LLMVRLLNKKINPVWLIFALFGLGIIGNALGFLS
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N p -phosphohistidine; sugar; phosphoenolpyruvate; glucosamine [Periplasm]; phosphoenolpyruvate; beta-D-glucose [Periplasm]; N-acetyl-D-glucosamine [Periplasm]; mannose [Periplasm]; fructose [Periplasm] [C]

Specific reaction: protein N p -phosphohistidine + sugar = protein histidine + sugar phosphate phosphoenolpyruvate + glucosamine [Periplasm] = D-glucosamine-6-phosphate [Cytoplasm] + pyruvate phosphoenolpyruvate + beta-D-glucose [Periplasm] = glucose-6-phosphate [Cytoplasm]

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7947968 [H]