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The map label for this gene is argO

Identifier: 209397283

GI number: 209397283

Start: 3910046

End: 3910681

Strand: Reverse

Name: argO

Synonym: ECH74115_4220

Alternate gene names: 209397283

Gene position: 3910681-3910046 (Counterclockwise)

Preceding gene: 209400812

Following gene: 209398049

Centisome position: 70.18

GC content: 50.63

Gene sequence:

>636_bases
GTGTTTTCTTATTACTTTCAAGGTCTTGCTCTTGGGGCAGCTATGATTCTGCCGCTCGGCCCACAAAATGCTTTTGTGAT
GAATCAGGGCATTCGTCGTCAGTACCACATTATGATTGCCTTACTTTGCGCTATCAGCGATTTGGTCCTGATTTGCGCGG
GGATTTTTGGTGGTAGCGCGTTATTGATGCAGTCGCCGTGGTTGCTGGCGCTGGTCACCTGGGGCGGCGTAGTCTTCTTG
CTGTGGTATGGTTTTGGCGCTTTTAAAACAGCGATGAGTAGTAATATTGAGTTAGCTAGTGCCGAAGTCCTGAAGCAAGG
CAGATGGAAAATTATCGCCACCATGTTGGCAGTGACCTGGCTGAATCCGCATGTTTACCTAGATACTTTTGTTGTACTGG
GCAGCCTTGGCGGGCAGCTTGACGTCGAACCAAAACGTTGGTTTGCGCTCGGGACAATTAGCGCCTCTTTCCTGTGGTTC
TTTGGTCTGGCTATTCTCGCAGCCTGGCTGGCACCGCGCCTGCGCACGGCAAAATCACAGCGCATTATCAATCTGGTAGT
GGGATGTGTCATGTGGTTTATAGCCTTGCAGCTGGCGAGAGACGGTATTGCTCATGCACAAGCCTTGTTCAGTTAG

Upstream 100 bases:

>100_bases
TTATTAGTTATTCTGATTGCCAATTAATATTATCAATTTCCGCTAATAACAATCCCGCGATATAGTCTCTGCATCAGATA
CTTAATTCGGAATATCCAAC

Downstream 100 bases:

>100_bases
GCGCTATCTGATGGAAAAATAAAACAGAGGCGCTAAGCTTGCCTCCAGAGATCCTGAATTTTGGGCAAGTCAATTAACAC
GGAGAGACTAACGTGAAGTT

Product: arginine exporter protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MFSYYFQGLALGAAMILPLGPQNAFVMNQGIRRQYHIMIALLCAISDLVLICAGIFGGSALLMQSPWLLALVTWGGVVFL
LWYGFGAFKTAMSSNIELASAEVLKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLDVEPKRWFALGTISASFLWF
FGLAILAAWLAPRLRTAKSQRIINLVVGCVMWFIALQLARDGIAHAQALFS

Sequences:

>Translated_211_residues
MFSYYFQGLALGAAMILPLGPQNAFVMNQGIRRQYHIMIALLCAISDLVLICAGIFGGSALLMQSPWLLALVTWGGVVFL
LWYGFGAFKTAMSSNIELASAEVLKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLDVEPKRWFALGTISASFLWF
FGLAILAAWLAPRLRTAKSQRIINLVVGCVMWFIALQLARDGIAHAQALFS
>Mature_211_residues
MFSYYFQGLALGAAMILPLGPQNAFVMNQGIRRQYHIMIALLCAISDLVLICAGIFGGSALLMQSPWLLALVTWGGVVFL
LWYGFGAFKTAMSSNIELASAEVLKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLDVEPKRWFALGTISASFLWF
FGLAILAAWLAPRLRTAKSQRIINLVVGCVMWFIALQLARDGIAHAQALFS

Specific function: Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine

COG id: COG1279

COG function: function code R; Lysine efflux permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LysE/ArgO transporter (TC 2.A.75) family

Homologues:

Organism=Escherichia coli, GI1789290, Length=211, Percent_Identity=98.1042654028436, Blast_Score=416, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGO_ECO57 (Q8XD10)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   B91103
- PIR:   E85948
- RefSeq:   NP_289490.1
- RefSeq:   NP_311821.1
- EnsemblBacteria:   EBESCT00000027977
- EnsemblBacteria:   EBESCT00000055176
- GeneID:   916374
- GeneID:   959537
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z4260
- KEGG:   ecs:ECs3794
- GeneTree:   EBGT00050000008905
- HOGENOM:   HBG683136
- OMA:   EHHLPVA
- ProtClustDB:   PRK09304
- BioCyc:   ECOL83334:ECS3794-MONOMER
- HAMAP:   MF_01901
- InterPro:   IPR004777
- InterPro:   IPR001123
- TIGRFAMs:   TIGR00948

Pfam domain/function: PF01810 LysE

EC number: NA

Molecular weight: Translated: 23202; Mature: 23202

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS00189 LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11549a70)-; HASH(0x11171a18)-; HASH(0x116b056c)-; HASH(0x11293398)-; HASH(0x11633f4c)-; HASH(0x102de8e0)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSYYFQGLALGAAMILPLGPQNAFVMNQGIRRQYHIMIALLCAISDLVLICAGIFGGSA
CCHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
LLMQSPWLLALVTWGGVVFLLWYGFGAFKTAMSSNIELASAEVLKQGRWKIIATMLAVTW
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHH
LNPHVYLDTFVVLGSLGGQLDVEPKRWFALGTISASFLWFFGLAILAAWLAPRLRTAKSQ
CCCHHHHHHHHHHHCCCCCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIINLVVGCVMWFIALQLARDGIAHAQALFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MFSYYFQGLALGAAMILPLGPQNAFVMNQGIRRQYHIMIALLCAISDLVLICAGIFGGSA
CCHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
LLMQSPWLLALVTWGGVVFLLWYGFGAFKTAMSSNIELASAEVLKQGRWKIIATMLAVTW
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHH
LNPHVYLDTFVVLGSLGGQLDVEPKRWFALGTISASFLWFFGLAILAAWLAPRLRTAKSQ
CCCHHHHHHHHHHHCCCCCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIINLVVGCVMWFIALQLARDGIAHAQALFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796