Click here to switch to the map view.

The map label for this gene is cptA [H]

Identifier: 209397001

GI number: 209397001

Start: 5058527

End: 5060260

Strand: Reverse

Name: cptA [H]

Synonym: ECH74115_5415

Alternate gene names: 209397001

Gene position: 5060260-5058527 (Counterclockwise)

Preceding gene: 209397772

Following gene: 209400613

Centisome position: 90.81

GC content: 50.17

Gene sequence:

>1734_bases
ATGCATTCCACAGAAGTCCAGGCTAAACCTCTTTTTAGCTGGAAAGCCCTGGGTTGGGCATTGCTCTACTTTTGGTTTTT
CTCTACTCTGCTACAGGCCATTATTTACATCAGTGGTTATAGTGGCACCAACGGCATTCGCGACTCGCTGTTATTCAGCT
CGCTGTGGTTAATTCCGGTATTCCTCTTTCCGAAGCGGATCAAAATTATTGCCGCAGTGATCGGCGTGGTGCTATGGGCG
GCCTCTCTGGCGGCGCTGTGCTACTACGTCATCTACGGTCAGGAGTTCTCGCAGAGCGTTCTGTTTGTGATGTTCGAAAC
CAACACCAACGAAGCCAGCGAGTATTTAAGCCAGTATTTCAGCCTGAAAATTGTGCTTATCGCGCTGGCCTATACGGCGG
TGGCAGTTCTGCTGTGGACACGCCTGCGCCCGGTCTATATTCCAAAGCCGTGGCGTTATGTTGTCTCTTTTGCCCTGCTT
TATGGCTTGATTCTGCATCCGATCGCCATGAATATGTTTATCAAAAACAAGCCGTTTGAGAAAACGTTGGATAACCTGGC
CTCGCGTATGGAGCCTGCCGCACCGTGGCAATTCCTGACCGGCTATTATCAGTATCGTCAGCAACTAAACTCGCTAACAA
AGCTACTGAATGAAAATAATGCCTTGCCGCCGCTGGCTAATTTCAAAGATGAATCGGGTAACGAACCGCGCACCTTAGTG
CTGGTGATTGGCGAGTCAACCCAGCGTGGACGCATGAGTCTGTACGGTTATCCGCGTGAAACCACGCCGGAGCTGAATGC
GCTGCATAAAACCGATCCGAATCTGACCGTGTTTAATAACGTAGTTACGTCTCGTCCGTACACCATTGAAATCCTGCAAC
AGGCGCTGACCTTTGCCAATGAAAAGAACCCGGATCTGTATCTGACGCAGCCGTCGCTGATGAACATGATGAAACAGGCG
GGTTATAAAACCTTCTGGATCACCAACCAGCAGACGATGACCGCCCGCAATACCATGCTGACGGTATTTTCGCGCCAGAC
CGACAAGCAGTACTACATGAACCAGCAACGTACGCAGAGTGCGCGTGAATACGACACTAACGTGCTGAAGCCGTTCCAGG
AAGTGCTGAAGGACCCTGCGCCGAAGAAACTGATCATCGTTCATCTGCTGGGTACGCATATCAAATACAAATACCGCTAC
CCGGAAAATCAGGGCAAGTTTGATGGCAATACCGATCATGTTCCGCCGGGATTAAACGCGGAAGAGCTGGAGTCATATAA
CGATTATGACAACGCTAACCTGTATAACGATCATGTGGTTGCCAGCCTGATTAAAGACTTTAAAGCAGCAGACCCGAACG
GTTTCCTGGTTTACTTCTCTGACCACGGTGAAGAGGTTTACGACACGCCGCCTCATAAAACCCAGGGGCGTAATGAGGAC
AACCCGACGCGTCATATGTACACCATTCCGTTCCTGCTGTGGACGTCGGAAAAATGGCAAGCGACTCATCCGCGTGATTT
CTCGCAGGATGTTGATCGTAAATACAGCCTTGCGGAACTGATCCACACCTGGTCAGATTTAGCGGGCTTATCTTACGACG
GTTACGATCCAACCCGTTCAGTGGTGAATCCGCAGTTCAAAGAAAATACCCGCTGGATTGGTAACCCGTACAAGAAAAAC
GCGCTGATCGATTACGACACGCTGCCGTATGGCGACCAGGTAGGTAATCAGTAA

Upstream 100 bases:

>100_bases
TTTCTGTCTGCATTTTATTCAAATTCTGGATATCCCTTCAGATATCCTTAAGGAATTGTCGGTAAATTCGGCGATATTTT
TTTCAAGACAGGTTCTTACT

Downstream 100 bases:

>100_bases
TTATCAGCCAGGCGCTATTTGCCGGATGCGACGCTTGACGCGTCTTATCCGGCCTACAGATCGCGGCGGTAGACTGGATA
AGGCGTTTACGCCACATCCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MHSTEVQAKPLFSWKALGWALLYFWFFSTLLQAIIYISGYSGTNGIRDSLLFSSLWLIPVFLFPKRIKIIAAVIGVVLWA
ASLAALCYYVIYGQEFSQSVLFVMFETNTNEASEYLSQYFSLKIVLIALAYTAVAVLLWTRLRPVYIPKPWRYVVSFALL
YGLILHPIAMNMFIKNKPFEKTLDNLASRMEPAAPWQFLTGYYQYRQQLNSLTKLLNENNALPPLANFKDESGNEPRTLV
LVIGESTQRGRMSLYGYPRETTPELNALHKTDPNLTVFNNVVTSRPYTIEILQQALTFANEKNPDLYLTQPSLMNMMKQA
GYKTFWITNQQTMTARNTMLTVFSRQTDKQYYMNQQRTQSAREYDTNVLKPFQEVLKDPAPKKLIIVHLLGTHIKYKYRY
PENQGKFDGNTDHVPPGLNAEELESYNDYDNANLYNDHVVASLIKDFKAADPNGFLVYFSDHGEEVYDTPPHKTQGRNED
NPTRHMYTIPFLLWTSEKWQATHPRDFSQDVDRKYSLAELIHTWSDLAGLSYDGYDPTRSVVNPQFKENTRWIGNPYKKN
ALIDYDTLPYGDQVGNQ

Sequences:

>Translated_577_residues
MHSTEVQAKPLFSWKALGWALLYFWFFSTLLQAIIYISGYSGTNGIRDSLLFSSLWLIPVFLFPKRIKIIAAVIGVVLWA
ASLAALCYYVIYGQEFSQSVLFVMFETNTNEASEYLSQYFSLKIVLIALAYTAVAVLLWTRLRPVYIPKPWRYVVSFALL
YGLILHPIAMNMFIKNKPFEKTLDNLASRMEPAAPWQFLTGYYQYRQQLNSLTKLLNENNALPPLANFKDESGNEPRTLV
LVIGESTQRGRMSLYGYPRETTPELNALHKTDPNLTVFNNVVTSRPYTIEILQQALTFANEKNPDLYLTQPSLMNMMKQA
GYKTFWITNQQTMTARNTMLTVFSRQTDKQYYMNQQRTQSAREYDTNVLKPFQEVLKDPAPKKLIIVHLLGTHIKYKYRY
PENQGKFDGNTDHVPPGLNAEELESYNDYDNANLYNDHVVASLIKDFKAADPNGFLVYFSDHGEEVYDTPPHKTQGRNED
NPTRHMYTIPFLLWTSEKWQATHPRDFSQDVDRKYSLAELIHTWSDLAGLSYDGYDPTRSVVNPQFKENTRWIGNPYKKN
ALIDYDTLPYGDQVGNQ
>Mature_577_residues
MHSTEVQAKPLFSWKALGWALLYFWFFSTLLQAIIYISGYSGTNGIRDSLLFSSLWLIPVFLFPKRIKIIAAVIGVVLWA
ASLAALCYYVIYGQEFSQSVLFVMFETNTNEASEYLSQYFSLKIVLIALAYTAVAVLLWTRLRPVYIPKPWRYVVSFALL
YGLILHPIAMNMFIKNKPFEKTLDNLASRMEPAAPWQFLTGYYQYRQQLNSLTKLLNENNALPPLANFKDESGNEPRTLV
LVIGESTQRGRMSLYGYPRETTPELNALHKTDPNLTVFNNVVTSRPYTIEILQQALTFANEKNPDLYLTQPSLMNMMKQA
GYKTFWITNQQTMTARNTMLTVFSRQTDKQYYMNQQRTQSAREYDTNVLKPFQEVLKDPAPKKLIIVHLLGTHIKYKYRY
PENQGKFDGNTDHVPPGLNAEELESYNDYDNANLYNDHVVASLIKDFKAADPNGFLVYFSDHGEEVYDTPPHKTQGRNED
NPTRHMYTIPFLLWTSEKWQATHPRDFSQDVDRKYSLAELIHTWSDLAGLSYDGYDPTRSVVNPQFKENTRWIGNPYKKN
ALIDYDTLPYGDQVGNQ

Specific function: Catalyzes the addition of a phosphoethanolamine moiety to the outer membrane lipopolysaccharide core [H]

COG id: COG2194

COG function: function code R; Predicted membrane-associated, metal-dependent hydrolase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoethanolamine transferase family. CptA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790392, Length=577, Percent_Identity=99.1334488734835, Blast_Score=1185, Evalue=0.0,
Organism=Escherichia coli, GI87082223, Length=481, Percent_Identity=23.7006237006237, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI87082286, Length=267, Percent_Identity=25.8426966292135, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1787035, Length=498, Percent_Identity=20.4819277108434, Blast_Score=76, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR012549
- InterPro:   IPR000917 [H]

Pfam domain/function: PF08019 DUF1705; PF00884 Sulfatase [H]

EC number: NA

Molecular weight: Translated: 66668; Mature: 66668

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSTEVQAKPLFSWKALGWALLYFWFFSTLLQAIIYISGYSGTNGIRDSLLFSSLWLIPV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
FLFPKRIKIIAAVIGVVLWAASLAALCYYVIYGQEFSQSVLFVMFETNTNEASEYLSQYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHH
SLKIVLIALAYTAVAVLLWTRLRPVYIPKPWRYVVSFALLYGLILHPIAMNMFIKNKPFE
HHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
KTLDNLASRMEPAAPWQFLTGYYQYRQQLNSLTKLLNENNALPPLANFKDESGNEPRTLV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEE
LVIGESTQRGRMSLYGYPRETTPELNALHKTDPNLTVFNNVVTSRPYTIEILQQALTFAN
EEECCCCCCCCEEEECCCCCCCCCHHHHHCCCCCCEEEHHHHCCCCHHHHHHHHHHHHCC
EKNPDLYLTQPSLMNMMKQAGYKTFWITNQQTMTARNTMLTVFSRQTDKQYYMNQQRTQS
CCCCCEEEECHHHHHHHHHCCCEEEEEECCCHHHHHHHEEEEHHCCCCHHHHHHHHHHHH
AREYDTNVLKPFQEVLKDPAPKKLIIVHLLGTHIKYKYRYPENQGKFDGNTDHVPPGLNA
HHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCH
EELESYNDYDNANLYNDHVVASLIKDFKAADPNGFLVYFSDHGEEVYDTPPHKTQGRNED
HHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCC
NPTRHMYTIPFLLWTSEKWQATHPRDFSQDVDRKYSLAELIHTWSDLAGLSYDGYDPTRS
CCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
VVNPQFKENTRWIGNPYKKNALIDYDTLPYGDQVGNQ
HCCCCHHCCCCCCCCCCCCCCEEECCCCCCCHHCCCC
>Mature Secondary Structure
MHSTEVQAKPLFSWKALGWALLYFWFFSTLLQAIIYISGYSGTNGIRDSLLFSSLWLIPV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
FLFPKRIKIIAAVIGVVLWAASLAALCYYVIYGQEFSQSVLFVMFETNTNEASEYLSQYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHH
SLKIVLIALAYTAVAVLLWTRLRPVYIPKPWRYVVSFALLYGLILHPIAMNMFIKNKPFE
HHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
KTLDNLASRMEPAAPWQFLTGYYQYRQQLNSLTKLLNENNALPPLANFKDESGNEPRTLV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEE
LVIGESTQRGRMSLYGYPRETTPELNALHKTDPNLTVFNNVVTSRPYTIEILQQALTFAN
EEECCCCCCCCEEEECCCCCCCCCHHHHHCCCCCCEEEHHHHCCCCHHHHHHHHHHHHCC
EKNPDLYLTQPSLMNMMKQAGYKTFWITNQQTMTARNTMLTVFSRQTDKQYYMNQQRTQS
CCCCCEEEECHHHHHHHHHCCCEEEEEECCCHHHHHHHEEEEHHCCCCHHHHHHHHHHHH
AREYDTNVLKPFQEVLKDPAPKKLIIVHLLGTHIKYKYRYPENQGKFDGNTDHVPPGLNA
HHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCH
EELESYNDYDNANLYNDHVVASLIKDFKAADPNGFLVYFSDHGEEVYDTPPHKTQGRNED
HHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCC
NPTRHMYTIPFLLWTSEKWQATHPRDFSQDVDRKYSLAELIHTWSDLAGLSYDGYDPTRS
CCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
VVNPQFKENTRWIGNPYKKNALIDYDTLPYGDQVGNQ
HCCCCHHCCCCCCCCCCCCCCEEECCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]