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The map label for this gene is rbsC

Identifier: 209396828

GI number: 209396828

Start: 4831827

End: 4832792

Strand: Direct

Name: rbsC

Synonym: ECH74115_5186

Alternate gene names: 209396828

Gene position: 4831827-4832792 (Clockwise)

Preceding gene: 209400209

Following gene: 209400606

Centisome position: 86.72

GC content: 53.31

Gene sequence:

>966_bases
ATGACAACCCAGACTGTCTCTGGTCGCCGTTATTTCACGAAAGCGTGGCTGATGGAGCAGAAATCGCTTATCGCTCTGCT
GGTGCTGATCGCGATTGTCTCGACGTTAAGCCCGAACTTTTTCACCATCAATAACTTATTCAATATTCTCCAGCAAACCT
CAGTGAACGCCATTATGGCGGTCGGGATGACGCTGGTGATCCTGACGTCGGGCATCGACTTGTCGGTAGGTTCTCTGTTG
GCGCTAACCGGCGCAGTTGCTGCATCTATCGTCGGCATTGAAGTCAATGCGCTGGTGGCTGTCGCTGCCGCTCTCGCGTT
AGGTGCCGCAATTGGTGCGGTAACCGGAGTGATTGTAGCGAAAGGTCGCGTCCAGGCGTTTATCGCTACGCTGGTTATGA
TGCTTTTACTGCGCGGCGTGACCATGGTTTATACCAACGGTAGCCCAGTGAATACCGGCTTTACTGAGAACGCCGATCTG
TTTGGCTGGTTTGGTATTGGTCGTCCGCTGGGCGTACCGACGCCAGTCTGGATCATGGGGATTGTCTTCCTCGCGGCCTG
GTACATGCTGCATCACACGCGTCTGGGGCGTTACATCTACGCGCTGGGCGGCAACGAAGCGGCAACGCGTCTTTCTGGTA
TCAACGTCAATAAAATCAAAATCATCGTCTATTCTCTTTGTGGTCTGCTGGCATCACTGGCCGGGATCATTGAAGTGGCG
CGTCTCTCCTCCGCACAACCCACGGCGGGGACTGGCTATGAGCTGGATGCTATTGCTGCGGTGGTTCTGGGCGGTACGAG
TCTGGCGGGCGGAAAAGGTCGCATTGTTGGGACGTTGATCGGCGCATTAATTCTTGGCTTCCTTAATAATGGATTGAATT
TGTTAGGTGTTTCCTCCTATTACCAGATGATCGTCAAAGCGGTGGTGATTTTGCTGGCGGTGCTGGTAGACAACAAAAAG
CAGTAA

Upstream 100 bases:

>100_bases
GGGCATCTCAGCGGGGAATTTACTCGTGAGCAGGCCACCCAGGAAGTGTTAATGGCTGCCGCTGTGGGCAAGCTTAATCG
CGTGAATCAGGAGTAAAAAA

Downstream 100 bases:

>100_bases
TAACGACTACAGGACATCTTGAATATGAACATGAAAAAACTGGCTACCCTGGTTTCCGCTGTTGCGCTAAGCGCCACCGT
CAGTGCGAATGCGATGGCAA

Product: ribose ABC transporter permease protein

Products: ADP; phosphate; ribose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MTTQTVSGRRYFTKAWLMEQKSLIALLVLIAIVSTLSPNFFTINNLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLL
ALTGAVAASIVGIEVNALVAVAAALALGAAIGAVTGVIVAKGRVQAFIATLVMMLLLRGVTMVYTNGSPVNTGFTENADL
FGWFGIGRPLGVPTPVWIMGIVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNKIKIIVYSLCGLLASLAGIIEVA
RLSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLVDNKK
Q

Sequences:

>Translated_321_residues
MTTQTVSGRRYFTKAWLMEQKSLIALLVLIAIVSTLSPNFFTINNLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLL
ALTGAVAASIVGIEVNALVAVAAALALGAAIGAVTGVIVAKGRVQAFIATLVMMLLLRGVTMVYTNGSPVNTGFTENADL
FGWFGIGRPLGVPTPVWIMGIVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNKIKIIVYSLCGLLASLAGIIEVA
RLSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLVDNKK
Q
>Mature_320_residues
TTQTVSGRRYFTKAWLMEQKSLIALLVLIAIVSTLSPNFFTINNLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLA
LTGAVAASIVGIEVNALVAVAAALALGAAIGAVTGVIVAKGRVQAFIATLVMMLLLRGVTMVYTNGSPVNTGFTENADLF
GWFGIGRPLGVPTPVWIMGIVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNKIKIIVYSLCGLLASLAGIIEVAR
LSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLVDNKKQ

Specific function: Part of the binding-protein-dependent transport system for ribose. Probably responsible for the translocation of the substrate across the membrane

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily

Homologues:

Organism=Escherichia coli, GI1790191, Length=321, Percent_Identity=100, Blast_Score=622, Evalue=1e-180,
Organism=Escherichia coli, GI1788896, Length=315, Percent_Identity=39.3650793650794, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1790524, Length=315, Percent_Identity=40, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI145693152, Length=310, Percent_Identity=35.8064516129032, Blast_Score=174, Evalue=9e-45,
Organism=Escherichia coli, GI1789992, Length=359, Percent_Identity=35.3760445682451, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI87082395, Length=304, Percent_Identity=36.5131578947368, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788471, Length=323, Percent_Identity=36.5325077399381, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI145693214, Length=326, Percent_Identity=36.8098159509202, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787793, Length=292, Percent_Identity=33.9041095890411, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787794, Length=292, Percent_Identity=29.7945205479452, Blast_Score=95, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RBSC_ECO57 (P0AGI3)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   D91215
- RefSeq:   NP_290389.1
- RefSeq:   NP_312719.1
- ProteinModelPortal:   P0AGI3
- EnsemblBacteria:   EBESCT00000024039
- EnsemblBacteria:   EBESCT00000058191
- GeneID:   915328
- GeneID:   960416
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z5251
- KEGG:   ecs:ECs4692
- GeneTree:   EBGT00050000010181
- HOGENOM:   HBG663180
- OMA:   GSPINTG
- ProtClustDB:   PRK09512
- BioCyc:   ECOL83334:ECS4692-MONOMER
- InterPro:   IPR001851

Pfam domain/function: PF02653 BPD_transp_2

EC number: NA

Molecular weight: Translated: 33452; Mature: 33321

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10436120)-; HASH(0x12a769c0)-; HASH(0x1321be70)-; HASH(0x12a3ee88)-; HASH(0x123eb944)-; HASH(0x12ee36fc)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQTVSGRRYFTKAWLMEQKSLIALLVLIAIVSTLSPNFFTINNLFNILQQTSVNAIMA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHH
VGMTLVILTSGIDLSVGSLLALTGAVAASIVGIEVNALVAVAAALALGAAIGAVTGVIVA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KGRVQAFIATLVMMLLLRGVTMVYTNGSPVNTGFTENADLFGWFGIGRPLGVPTPVWIMG
CHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHH
IVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNKIKIIVYSLCGLLASLAGIIEVA
HHHHHHHHHHHHHHHCCEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RLSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLLGVSSY
HHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHH
YQMIVKAVVILLAVLVDNKKQ
HHHHHHHHHHHHHHHHCCCCH
>Mature Secondary Structure 
TTQTVSGRRYFTKAWLMEQKSLIALLVLIAIVSTLSPNFFTINNLFNILQQTSVNAIMA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHH
VGMTLVILTSGIDLSVGSLLALTGAVAASIVGIEVNALVAVAAALALGAAIGAVTGVIVA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KGRVQAFIATLVMMLLLRGVTMVYTNGSPVNTGFTENADLFGWFGIGRPLGVPTPVWIMG
CHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHH
IVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNKIKIIVYSLCGLLASLAGIIEVA
HHHHHHHHHHHHHHHCCEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RLSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLLGVSSY
HHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHH
YQMIVKAVVILLAVLVDNKKQ
HHHHHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ribose [Periplasm]; H2O [C]

Specific reaction: ATP + ribose [Periplasm] + H2O = ADP + phosphate + ribose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796