Click here to switch to the map view.

The map label for this gene is yegX

Identifier: 209396750

GI number: 209396750

Start: 2853160

End: 2853978

Strand: Reverse

Name: yegX

Synonym: ECH74115_3081

Alternate gene names: 209396750

Gene position: 2853978-2853160 (Counterclockwise)

Preceding gene: 209400323

Following gene: 209399375

Centisome position: 51.22

GC content: 48.47

Gene sequence:

>819_bases
ATGCAGCTAAGAATTACCAGTCGAAAAAAACTCACCGCTCTATTATGCGCTCTTGGGCTAATTTCCATCGTTGCAATTTA
TCCGCGTCAGACGGTGAATTTTTTCTATTCGACAGCAGTTCAGATTACAGACTACATCCACTTCTACGGTTATCGCCCGG
TTAAATCTTTCGCTATTCATATTCCTGCCAGTTACACCATTCACGGAATAGATGTTTCGCGCTGGCAGGAGCGGATCGAC
TGGCAGCGGGTGGCAAAAATGCGCGATAACGGTATCCGCTTACAATTTGCCTTTATCAAGGCGACGGAAGGCGAAAAGCT
GGTGGACCCCTATTTTTCGCGTAACTGGCAACTAAGCCGCGAAAATGGCCTGCTGCGCGGGGCGTATCATTATTTCTCCC
CGTCGGTAGCAGCGCCTGTTCAGGCGCGATTATTTCTGCAAACGGTGGATTTCTCACAAGGCGATTTCCCTGCCGTGCTG
GACGTAGAAGAACGGGGAAAATTATCGGCAAAAGAATTACGCAAGCGGGTAAGTCAGTGGCTAAAAATGGTCGAAAAAAG
TACGGGAAAAAAGCCGGTTATTTACTCAGGAGCCGTTTTTTATCACACCAATCTGGCGGGCTATTTCAATGAATATCCGT
GGTGGGTGGCTCACTACTATCAACGTCGCCCGGACAATGACGGCATGGCCTGGCGTTTCTGGCAGCATTCCGACCGTGGG
CAGGTAGATGGCATTAATGGTTCGGTGGATTTTAATGTGTTTAATGGCACAGAGGAGGAGTTGCAGGCATTCGTTGATGG
GATTAAAGAAACGCCTTAA

Upstream 100 bases:

>100_bases
ATTGGTCCGGTTCACCACTTCCACGCCTGGTGGTGAGCACCGTACTATAGCTGCTTTGGTTATTGTCAGCCTTTGGCACT
GACATTCAGGGATGAAACCA

Downstream 100 bases:

>100_bases
ATAAGAAGCAGTGATATACTCCCACCAGACTCCCTGGCAGGAAAAAGACAAATGGAACAAGCGCATACCCAGCTGATTGC
CCAACTGAACGAGCGTATTT

Product: glycosyl hydrolase family 25

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MQLRITSRKKLTALLCALGLISIVAIYPRQTVNFFYSTAVQITDYIHFYGYRPVKSFAIHIPASYTIHGIDVSRWQERID
WQRVAKMRDNGIRLQFAFIKATEGEKLVDPYFSRNWQLSRENGLLRGAYHYFSPSVAAPVQARLFLQTVDFSQGDFPAVL
DVEERGKLSAKELRKRVSQWLKMVEKSTGKKPVIYSGAVFYHTNLAGYFNEYPWWVAHYYQRRPDNDGMAWRFWQHSDRG
QVDGINGSVDFNVFNGTEEELQAFVDGIKETP

Sequences:

>Translated_272_residues
MQLRITSRKKLTALLCALGLISIVAIYPRQTVNFFYSTAVQITDYIHFYGYRPVKSFAIHIPASYTIHGIDVSRWQERID
WQRVAKMRDNGIRLQFAFIKATEGEKLVDPYFSRNWQLSRENGLLRGAYHYFSPSVAAPVQARLFLQTVDFSQGDFPAVL
DVEERGKLSAKELRKRVSQWLKMVEKSTGKKPVIYSGAVFYHTNLAGYFNEYPWWVAHYYQRRPDNDGMAWRFWQHSDRG
QVDGINGSVDFNVFNGTEEELQAFVDGIKETP
>Mature_272_residues
MQLRITSRKKLTALLCALGLISIVAIYPRQTVNFFYSTAVQITDYIHFYGYRPVKSFAIHIPASYTIHGIDVSRWQERID
WQRVAKMRDNGIRLQFAFIKATEGEKLVDPYFSRNWQLSRENGLLRGAYHYFSPSVAAPVQARLFLQTVDFSQGDFPAVL
DVEERGKLSAKELRKRVSQWLKMVEKSTGKKPVIYSGAVFYHTNLAGYFNEYPWWVAHYYQRRPDNDGMAWRFWQHSDRG
QVDGINGSVDFNVFNGTEEELQAFVDGIKETP

Specific function: Unknown

COG id: COG3757

COG function: function code M; Lyzozyme M1 (1,4-beta-N-acetylmuramidase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 25 family

Homologues:

Organism=Escherichia coli, GI87082043, Length=272, Percent_Identity=97.4264705882353, Blast_Score=553, Evalue=1e-159,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YEGX_ECO57 (Q8X7H0)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   A90992
- PIR:   C85837
- RefSeq:   NP_288604.1
- RefSeq:   NP_310932.1
- ProteinModelPortal:   Q8X7H0
- SMR:   Q8X7H0
- EnsemblBacteria:   EBESCT00000024322
- EnsemblBacteria:   EBESCT00000057071
- GeneID:   916608
- GeneID:   956825
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z3266
- KEGG:   ecs:ECs2905
- GeneTree:   EBGT00050000011081
- HOGENOM:   HBG580490
- OMA:   RRWAFWQ
- ProtClustDB:   CLSK880290
- BioCyc:   ECOL83334:ECS2905-MONOMER
- InterPro:   IPR002053
- InterPro:   IPR008270
- InterPro:   IPR017853
- InterPro:   IPR018077
- InterPro:   IPR013781
- Gene3D:   G3DSA:3.20.20.80
- SMART:   SM00641

Pfam domain/function: PF01183 Glyco_hydro_25; SSF51445 Glyco_hydro_cat

EC number: NA

Molecular weight: Translated: 31569; Mature: 31569

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS00953 GLYCOSYL_HYDROL_F25

Important sites: ACT_SITE 163-163

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLRITSRKKLTALLCALGLISIVAIYPRQTVNFFYSTAVQITDYIHFYGYRPVKSFAIH
CEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEE
IPASYTIHGIDVSRWQERIDWQRVAKMRDNGIRLQFAFIKATEGEKLVDPYFSRNWQLSR
ECCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCHHHCCCEEEEC
ENGLLRGAYHYFSPSVAAPVQARLFLQTVDFSQGDFPAVLDVEERGKLSAKELRKRVSQW
CCCEEEEEHHHCCCCCCCCHHHEEEEEEECCCCCCCCEEEEHHHCCCCCHHHHHHHHHHH
LKMVEKSTGKKPVIYSGAVFYHTNLAGYFNEYPWWVAHYYQRRPDNDGMAWRFWQHSDRG
HHHHHHCCCCCCEEEECEEEEECCHHHHHCCCCHHHHHHHHCCCCCCCCEEEEEECCCCC
QVDGINGSVDFNVFNGTEEELQAFVDGIKETP
CCCCCCCEEEEEEECCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQLRITSRKKLTALLCALGLISIVAIYPRQTVNFFYSTAVQITDYIHFYGYRPVKSFAIH
CEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEE
IPASYTIHGIDVSRWQERIDWQRVAKMRDNGIRLQFAFIKATEGEKLVDPYFSRNWQLSR
ECCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCHHHCCCEEEEC
ENGLLRGAYHYFSPSVAAPVQARLFLQTVDFSQGDFPAVLDVEERGKLSAKELRKRVSQW
CCCEEEEEHHHCCCCCCCCHHHEEEEEEECCCCCCCCEEEEHHHCCCCCHHHHHHHHHHH
LKMVEKSTGKKPVIYSGAVFYHTNLAGYFNEYPWWVAHYYQRRPDNDGMAWRFWQHSDRG
HHHHHHCCCCCCEEEECEEEEECCHHHHHCCCCHHHHHHHHCCCCCCCCEEEEEECCCCC
QVDGINGSVDFNVFNGTEEELQAFVDGIKETP
CCCCCCCEEEEEEECCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796