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The map label for this gene is hmuT [H]

Identifier: 209396547

GI number: 209396547

Start: 4495266

End: 4496120

Strand: Direct

Name: hmuT [H]

Synonym: ECH74115_4861

Alternate gene names: 209396547

Gene position: 4495266-4496120 (Clockwise)

Preceding gene: 209397132

Following gene: 209395960

Centisome position: 80.67

GC content: 53.1

Gene sequence:

>855_bases
GTGGCCTCTGCCGCGAAGACCGCAGTAAAACGTAAAAAATTGTTTACGGCAGTACTGGCTCTTAGCTGGGCTTTTAGCGT
AACGGCTGCCGAACGTATCGTGGTCGCAGGAGGATCGCTGACGGAGCTAATCTACGCGATGGGCGCTGGCGAACGCGTGG
TTGGTGTCGATGAAACGACATCTTATCCACCAGAAACCGCCAAACTGCCGCATATTGGCTACTGGAAACAACTCAGCAGC
GAAGGCATTTTGTCACTTCGCCCGGATAGCGTAATTACCTGGCAGGATGCCGGGCCACAAATTGTGCTCGACCAACTACG
AGCGCAGAAAGTCAACGTCGTCACCCTGCCGCGTGTGCCTGCCACCCTTCAGCAGATGTACGCCAACATTCGCCAACTGG
CAAAAACGCTACAGGTTCCTGAACAAGGCGAGGCGCTGGTGACACAAATCAGCCAACGCCTGGAGCGAGTACAGCAAAAC
GTGGCGACCAAAAAAGCCCCGGTTAAAGCCATGTTTATTCTCTCCGCAGGCGGAAGTGCGCCACAAGTTGCCGGTAAAGG
CAGCGTCGCGGACGCCATTCTTTCGCTTGCCGGAGCAGAAAACGTCGCTACCCACCAGCAGTACAAAAGCTACAGTGCAG
AATCACTGATTGCGGCTAATCCAGAAGTGATTGTCGTAACCTCACAAATGGTCGATGGCGATATTAATCGGCTACGTTCT
ATTGCTGGAATTACCCACACTGCCGCATGGAAAAACCAGCGCATTATCACCGTTGATCAAAACCTGATTCTGGGAATGGG
TCCGCGTATTGCTGATGTCGTTGAGTCTTTACACCAGCAGCTTTGGCCGCAATAA

Upstream 100 bases:

>100_bases
TAATCATGATCATTCTCAATTTGATAAGAGTTCTCATATTATGCCAAGGATCATCACCAGGCCGTTTCTTTTTTCCCCAC
TGACGTTATGTATTTCAGCC

Downstream 100 bases:

>100_bases
ATGGATTTAAATCAGACGAATGAACGCAAATAACACCCTGGATCTCACGCCACATTTTGCTTTAGACGGTGATCAGCCAT
TTAAAGACAGGCGCGCCATG

Product: periplasmic-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MASAAKTAVKRKKLFTAVLALSWAFSVTAAERIVVAGGSLTELIYAMGAGERVVGVDETTSYPPETAKLPHIGYWKQLSS
EGILSLRPDSVITWQDAGPQIVLDQLRAQKVNVVTLPRVPATLQQMYANIRQLAKTLQVPEQGEALVTQISQRLERVQQN
VATKKAPVKAMFILSAGGSAPQVAGKGSVADAILSLAGAENVATHQQYKSYSAESLIAANPEVIVVTSQMVDGDINRLRS
IAGITHTAAWKNQRIITVDQNLILGMGPRIADVVESLHQQLWPQ

Sequences:

>Translated_284_residues
MASAAKTAVKRKKLFTAVLALSWAFSVTAAERIVVAGGSLTELIYAMGAGERVVGVDETTSYPPETAKLPHIGYWKQLSS
EGILSLRPDSVITWQDAGPQIVLDQLRAQKVNVVTLPRVPATLQQMYANIRQLAKTLQVPEQGEALVTQISQRLERVQQN
VATKKAPVKAMFILSAGGSAPQVAGKGSVADAILSLAGAENVATHQQYKSYSAESLIAANPEVIVVTSQMVDGDINRLRS
IAGITHTAAWKNQRIITVDQNLILGMGPRIADVVESLHQQLWPQ
>Mature_283_residues
ASAAKTAVKRKKLFTAVLALSWAFSVTAAERIVVAGGSLTELIYAMGAGERVVGVDETTSYPPETAKLPHIGYWKQLSSE
GILSLRPDSVITWQDAGPQIVLDQLRAQKVNVVTLPRVPATLQQMYANIRQLAKTLQVPEQGEALVTQISQRLERVQQNV
ATKKAPVKAMFILSAGGSAPQVAGKGSVADAILSLAGAENVATHQQYKSYSAESLIAANPEVIVVTSQMVDGDINRLRSI
AGITHTAAWKNQRIITVDQNLILGMGPRIADVVESLHQQLWPQ

Specific function: Part of the binding-protein-dependent transport system for hemin [H]

COG id: COG4558

COG function: function code P; ABC-type hemin transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786353, Length=220, Percent_Identity=29.5454545454545, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 30553; Mature: 30421

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASAAKTAVKRKKLFTAVLALSWAFSVTAAERIVVAGGSLTELIYAMGAGERVVGVDETT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCHHHHHHHHHCCCCEEEECCCCC
SYPPETAKLPHIGYWKQLSSEGILSLRPDSVITWQDAGPQIVLDQLRAQKVNVVTLPRVP
CCCCCCCCCCCCHHHHHHCCCCCEEECCCCEEEECCCCCHHHHHHHHHCCCCEEEECCCC
ATLQQMYANIRQLAKTLQVPEQGEALVTQISQRLERVQQNVATKKAPVKAMFILSAGGSA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCC
PQVAGKGSVADAILSLAGAENVATHQQYKSYSAESLIAANPEVIVVTSQMVDGDINRLRS
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCHHEECCCCEEEEEHHHHCCHHHHHHH
IAGITHTAAWKNQRIITVDQNLILGMGPRIADVVESLHQQLWPQ
HHCCHHHHHCCCCEEEEECCCEEECCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASAAKTAVKRKKLFTAVLALSWAFSVTAAERIVVAGGSLTELIYAMGAGERVVGVDETT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCHHHHHHHHHCCCCEEEECCCCC
SYPPETAKLPHIGYWKQLSSEGILSLRPDSVITWQDAGPQIVLDQLRAQKVNVVTLPRVP
CCCCCCCCCCCCHHHHHHCCCCCEEECCCCEEEECCCCCHHHHHHHHHCCCCEEEECCCC
ATLQQMYANIRQLAKTLQVPEQGEALVTQISQRLERVQQNVATKKAPVKAMFILSAGGSA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCC
PQVAGKGSVADAILSLAGAENVATHQQYKSYSAESLIAANPEVIVVTSQMVDGDINRLRS
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCHHEECCCCEEEEEHHHHCCHHHHHHH
IAGITHTAAWKNQRIITVDQNLILGMGPRIADVVESLHQQLWPQ
HHCCHHHHHCCCCEEEEECCCEEECCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9026634; 11586360; 12142430 [H]