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The map label for this gene is pagC [H]

Identifier: 209396143

GI number: 209396143

Start: 3962226

End: 3962759

Strand: Reverse

Name: pagC [H]

Synonym: ECH74115_4278

Alternate gene names: 209396143

Gene position: 3962759-3962226 (Counterclockwise)

Preceding gene: 209396733

Following gene: 209396139

Centisome position: 71.12

GC content: 39.89

Gene sequence:

>534_bases
ATGAGTGGTTCAAGACTGGCTGATAATCATACGCTATCGGCTGGTTATGCTCAGAGTAAGGTACAGGACTTTAAGAATAT
TAAAGGAGTGAATCTGCAATATCGATATGAGTGGGATTCTCCGGTCAGTGTCGTCGGGAGTTTTTCGTATATGAAAGGTG
ATTGGGCGGACAGTCATCGCGATGAAGCTGACGATTTTTACAGACATCAGGCTGATATTAAATATTATTCATTTCTCGCA
GGCCCAGCTTATCGTCTGAATGACTATATCAGTTTTTATGGTTTGGTGGGGATATCTCATACTAAAGCGAAGGGAGATTA
TGAGTGGAGAAACAGTGTGGGTGCTGATGAGTCTGATGGATATTTAAGTGAGTCTGTATCAAAAAAATCCACTGATTTTG
CTTATGCAGCTGGTGTTATTATTAATCCGTGGGGCAATATGTCTGTAAATGTTGGGTATGAGGGAACTAAAGCAGATATA
TATGGAAAACATTCGGTCAATGGATTTACTGTTGGAGTTGGTTATCGTTTTTAA

Upstream 100 bases:

>100_bases
TGAGATGTGTGGTCCTTTTTGATTTTCAGAAATCATTTATTAATGAAGGAGGGTTAAATGAAAAAAACTCGTTATAATTT
CAGTAATGATATTATATGTT

Downstream 100 bases:

>100_bases
TCATTAGACGGGACTGGATAATTGCACTTGCGTAGTGAAGTTTACTAAATGTTTGTATTTTAATGAAGTATTCGACATAT
TCCCTTCAGACGGAATATGT

Product: outer membrane invasion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MSGSRLADNHTLSAGYAQSKVQDFKNIKGVNLQYRYEWDSPVSVVGSFSYMKGDWADSHRDEADDFYRHQADIKYYSFLA
GPAYRLNDYISFYGLVGISHTKAKGDYEWRNSVGADESDGYLSESVSKKSTDFAYAAGVIINPWGNMSVNVGYEGTKADI
YGKHSVNGFTVGVGYRF

Sequences:

>Translated_177_residues
MSGSRLADNHTLSAGYAQSKVQDFKNIKGVNLQYRYEWDSPVSVVGSFSYMKGDWADSHRDEADDFYRHQADIKYYSFLA
GPAYRLNDYISFYGLVGISHTKAKGDYEWRNSVGADESDGYLSESVSKKSTDFAYAAGVIINPWGNMSVNVGYEGTKADI
YGKHSVNGFTVGVGYRF
>Mature_176_residues
SGSRLADNHTLSAGYAQSKVQDFKNIKGVNLQYRYEWDSPVSVVGSFSYMKGDWADSHRDEADDFYRHQADIKYYSFLAG
PAYRLNDYISFYGLVGISHTKAKGDYEWRNSVGADESDGYLSESVSKKSTDFAYAAGVIINPWGNMSVNVGYEGTKADIY
GKHSVNGFTVGVGYRF

Specific function: Essential for full virulence and survival within macrophages [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ail/ompX/pagC/lom family [H]

Homologues:

Organism=Escherichia coli, GI1787034, Length=178, Percent_Identity=34.2696629213483, Blast_Score=87, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000758
- InterPro:   IPR011250 [H]

Pfam domain/function: PF06316 Ail_Lom [H]

EC number: NA

Molecular weight: Translated: 19764; Mature: 19633

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00695 ENT_VIR_OMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSRLADNHTLSAGYAQSKVQDFKNIKGVNLQYRYEWDSPVSVVGSFSYMKGDWADSHR
CCCCCCCCCCEECCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCHHCCCCCCCCCC
DEADDFYRHQADIKYYSFLAGPAYRLNDYISFYGLVGISHTKAKGDYEWRNSVGADESDG
CCHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHEEECCCCCCCCCCHHHHCCCCCCCCC
YLSESVSKKSTDFAYAAGVIINPWGNMSVNVGYEGTKADIYGKHSVNGFTVGVGYRF
HHHHHHCCCCCCEEEEEEEEECCCCCEEEEECCCCCCEEEEECCCCCEEEEEEEECC
>Mature Secondary Structure 
SGSRLADNHTLSAGYAQSKVQDFKNIKGVNLQYRYEWDSPVSVVGSFSYMKGDWADSHR
CCCCCCCCCEECCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCHHCCCCCCCCCC
DEADDFYRHQADIKYYSFLAGPAYRLNDYISFYGLVGISHTKAKGDYEWRNSVGADESDG
CCHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHEEECCCCCCCCCCHHHHCCCCCCCCC
YLSESVSKKSTDFAYAAGVIINPWGNMSVNVGYEGTKADIYGKHSVNGFTVGVGYRF
HHHHHHCCCCCCEEEEEEEEECCCCCEEEEECCCCCCEEEEECCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1846140; 11677609 [H]