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The map label for this gene is invG [H]

Identifier: 209395847

GI number: 209395847

Start: 3836831

End: 3838534

Strand: Reverse

Name: invG [H]

Synonym: ECH74115_4149

Alternate gene names: 209395847

Gene position: 3838534-3836831 (Counterclockwise)

Preceding gene: 209396397

Following gene: 209400791

Centisome position: 68.89

GC content: 38.79

Gene sequence:

>1704_bases
ATGAAAATAAAATTACGCATTACTATTATATTAATTTCAGTCTTATGCATTTTTAATGGATTATTGACTCCTGGTGCATA
TGCCGCAGCAGCGAATGGATACGTAGCAAATAAAGAAAATCTACGTAGTTTTTTTGAAACGGTTTCATCATATGCGGGTA
AGCCTACAATAGTTAGTAAGCTTGCCATGAAGAAACAGATCAGCGGAAATTTTGATTTAACAGAACCCTATGCCTTGATT
GAACGCCTGTCGGCACAGATGGGGCTTATTTGGTATGATGATGGCAAAGCTATTTATATCTATGACTCATCAGAGATGCG
TAATGCATTGATTAATCTGAGAAAGGTATCGACGAATGAGTTTAATAATTTCTTAAAAAAATCGGGTCTGTATAACTCTC
GTTATGAAATTAAAGGGGACGGCAATGGTACTTTCTATGTATCGGGGCCACCGGTTTATGTTGACCTGGTCGTTAATGCT
GCGAAATTAATGGAGCAAAACAGCGATGGCATTGAGATCGGTCGAAATAAAGTAGGAATAATTCATCTGGTCAACACATT
CGTTAATGACCGGACTTATGAGTTACGTGGCGAAAAGATAGTTATTCCTGGCATGGCAAAAGTACTATCGACGTTGTTAA
ATAATAACATTAAGCAAAGCACAGGGGTGAACGTACTTTCTGAAATTTCAAGTCGTCAACAACTAAAAAACGTATCACGT
ATGCCTCCTTTTCCTGGGGCTGAAGAAGATGATGACCTACAAGTAGAGAAAATAATATCGACAGCAGGAGCGCCAGAGAC
TGACGATATACAAATTATTGCATATCCTGATACCAACAGTTTACTTGTTAAAGGAACAGTATCTCAGGTTGATTTTATCG
AGAAGTTAGTAGCTACGCTTGATATTCCAAAGCGACACATTGAATTATCTTTATGGATAATAGATATTGATAAGACTGAT
CTAGAACAGCTAGGTGCTGACTGGTCGGGCACGATAAAAATTGGATCCAGCTTAAGTGCATCATTTAATAATTCAGGTTC
AATTAGTACCCTTGATGGGACACAGTTTATTGCAACAATACAGGCACTTGCACAAAAAAGAAGAGCCGCCGTTGTTGCTC
GTCCCGTCGTTTTAACACAAGAGAATATTCCTGCTATATTTGATAATAACCGCACTTTCTATACTAAATTAGTCGGCGAG
CGTACTGCGGAATTGGATGAAGTAACCTATGGTACGATGATTAGCGTGCTACCACGATTTGCTGCGCGAAATCAAATTGA
ATTACTCTTGAATATTGAAGATGGAAATGAAATCAATTCCGACAAGACCAATGTTGATGATCTGCCTCAGGTTGGTAGAA
CACTTATAAGTACTATTGCACGCGTGCCCCAAGGGAAAAGTCTTTTGATTGGGGGATATACACGCGATACGAATACCTAT
GAAAGTCGCAAGATCCCAATATTAGGCAGCATTCCATTTATTGGTAAATTATTTGGTTATGAAGGAACAAATGCGAATAA
CATCGTTCGTGTCTTTCTTATTGAGCCAAGAGAGATCGATGAACGCATGATGAATAATGCGAATGAGGCTGCGGTTGATG
CCAGAGCGATTACACAGCAAATGGCAAAAAATAAAGAAATCAACGATGAATTACTGCAGAAATGGATAAAAACTTACCTG
AATCGTGAAGTCGTCGGAGGATAG

Upstream 100 bases:

>100_bases
CAACTATTGCGCATAAATATGGTTACTCGTCCTCATCACACTTTTCAGCCGAAGTAAAAAGCCGGTTAGGAAAAACACCG
AGAGAACTATGTAAAAAGTT

Downstream 100 bases:

>100_bases
TGAAATGGCGATTCATGTAGAGCATGTCGGTGTATTAGAAAGAGCCAGGGAAGTTTCTCGCTTAGAGGACATTATCACAG
AAGATAATGAAGACATTGAA

Product: type III secretion outer membrane pore, YscC/HrcC family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 567; Mature: 567

Protein sequence:

>567_residues
MKIKLRITIILISVLCIFNGLLTPGAYAAAANGYVANKENLRSFFETVSSYAGKPTIVSKLAMKKQISGNFDLTEPYALI
ERLSAQMGLIWYDDGKAIYIYDSSEMRNALINLRKVSTNEFNNFLKKSGLYNSRYEIKGDGNGTFYVSGPPVYVDLVVNA
AKLMEQNSDGIEIGRNKVGIIHLVNTFVNDRTYELRGEKIVIPGMAKVLSTLLNNNIKQSTGVNVLSEISSRQQLKNVSR
MPPFPGAEEDDDLQVEKIISTAGAPETDDIQIIAYPDTNSLLVKGTVSQVDFIEKLVATLDIPKRHIELSLWIIDIDKTD
LEQLGADWSGTIKIGSSLSASFNNSGSISTLDGTQFIATIQALAQKRRAAVVARPVVLTQENIPAIFDNNRTFYTKLVGE
RTAELDEVTYGTMISVLPRFAARNQIELLLNIEDGNEINSDKTNVDDLPQVGRTLISTIARVPQGKSLLIGGYTRDTNTY
ESRKIPILGSIPFIGKLFGYEGTNANNIVRVFLIEPREIDERMMNNANEAAVDARAITQQMAKNKEINDELLQKWIKTYL
NREVVGG

Sequences:

>Translated_567_residues
MKIKLRITIILISVLCIFNGLLTPGAYAAAANGYVANKENLRSFFETVSSYAGKPTIVSKLAMKKQISGNFDLTEPYALI
ERLSAQMGLIWYDDGKAIYIYDSSEMRNALINLRKVSTNEFNNFLKKSGLYNSRYEIKGDGNGTFYVSGPPVYVDLVVNA
AKLMEQNSDGIEIGRNKVGIIHLVNTFVNDRTYELRGEKIVIPGMAKVLSTLLNNNIKQSTGVNVLSEISSRQQLKNVSR
MPPFPGAEEDDDLQVEKIISTAGAPETDDIQIIAYPDTNSLLVKGTVSQVDFIEKLVATLDIPKRHIELSLWIIDIDKTD
LEQLGADWSGTIKIGSSLSASFNNSGSISTLDGTQFIATIQALAQKRRAAVVARPVVLTQENIPAIFDNNRTFYTKLVGE
RTAELDEVTYGTMISVLPRFAARNQIELLLNIEDGNEINSDKTNVDDLPQVGRTLISTIARVPQGKSLLIGGYTRDTNTY
ESRKIPILGSIPFIGKLFGYEGTNANNIVRVFLIEPREIDERMMNNANEAAVDARAITQQMAKNKEINDELLQKWIKTYL
NREVVGG
>Mature_567_residues
MKIKLRITIILISVLCIFNGLLTPGAYAAAANGYVANKENLRSFFETVSSYAGKPTIVSKLAMKKQISGNFDLTEPYALI
ERLSAQMGLIWYDDGKAIYIYDSSEMRNALINLRKVSTNEFNNFLKKSGLYNSRYEIKGDGNGTFYVSGPPVYVDLVVNA
AKLMEQNSDGIEIGRNKVGIIHLVNTFVNDRTYELRGEKIVIPGMAKVLSTLLNNNIKQSTGVNVLSEISSRQQLKNVSR
MPPFPGAEEDDDLQVEKIISTAGAPETDDIQIIAYPDTNSLLVKGTVSQVDFIEKLVATLDIPKRHIELSLWIIDIDKTD
LEQLGADWSGTIKIGSSLSASFNNSGSISTLDGTQFIATIQALAQKRRAAVVARPVVLTQENIPAIFDNNRTFYTKLVGE
RTAELDEVTYGTMISVLPRFAARNQIELLLNIEDGNEINSDKTNVDDLPQVGRTLISTIARVPQGKSLLIGGYTRDTNTY
ESRKIPILGSIPFIGKLFGYEGTNANNIVRVFLIEPREIDERMMNNANEAAVDARAITQQMAKNKEINDELLQKWIKTYL
NREVVGG

Specific function: Involved in the invasion of the cells of the intestinal epithelium. Could be necessary for the export of invasion related determinants [H]

COG id: COG1450

COG function: function code NU; Type II secretory pathway, component PulD

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=280, Percent_Identity=26.7857142857143, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005644
- InterPro:   IPR004846
- InterPro:   IPR004845
- InterPro:   IPR003522 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N [H]

EC number: NA

Molecular weight: Translated: 62795; Mature: 62795

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKLRITIILISVLCIFNGLLTPGAYAAAANGYVANKENLRSFFETVSSYAGKPTIVSK
CEEEEEEHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
LAMKKQISGNFDLTEPYALIERLSAQMGLIWYDDGKAIYIYDSSEMRNALINLRKVSTNE
HHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEECCCEEEEECCHHHHHHHHHHHHCCHHH
FNNFLKKSGLYNSRYEIKGDGNGTFYVSGPPVYVDLVVNAAKLMEQNSDGIEIGRNKVGI
HHHHHHHCCCCCCCEEEEECCCEEEEECCCCEEEEHHHHHHHHHHCCCCCCEECCCCEEE
IHLVNTFVNDRTYELRGEKIVIPGMAKVLSTLLNNNIKQSTGVNVLSEISSRQQLKNVSR
EEEEHHHHCCCEEEECCCEEEECCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHC
MPPFPGAEEDDDLQVEKIISTAGAPETDDIQIIAYPDTNSLLVKGTVSQVDFIEKLVATL
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHH
DIPKRHIELSLWIIDIDKTDLEQLGADWSGTIKIGSSLSASFNNSGSISTLDGTQFIATI
CCCCCEEEEEEEEEECCCHHHHHHCCCCCCEEEECCCCCCCCCCCCCEEEECCHHHHHHH
QALAQKRRAAVVARPVVLTQENIPAIFDNNRTFYTKLVGERTAELDEVTYGTMISVLPRF
HHHHHHHHHHHEECCEEEECCCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
AARNQIELLLNIEDGNEINSDKTNVDDLPQVGRTLISTIARVPQGKSLLIGGYTRDTNTY
HCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCC
ESRKIPILGSIPFIGKLFGYEGTNANNIVRVFLIEPREIDERMMNNANEAAVDARAITQQ
CCCCCCEEECCCHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHCCCCHHHHHHHHHHHH
MAKNKEINDELLQKWIKTYLNREVVGG
HHCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKIKLRITIILISVLCIFNGLLTPGAYAAAANGYVANKENLRSFFETVSSYAGKPTIVSK
CEEEEEEHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
LAMKKQISGNFDLTEPYALIERLSAQMGLIWYDDGKAIYIYDSSEMRNALINLRKVSTNE
HHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEECCCEEEEECCHHHHHHHHHHHHCCHHH
FNNFLKKSGLYNSRYEIKGDGNGTFYVSGPPVYVDLVVNAAKLMEQNSDGIEIGRNKVGI
HHHHHHHCCCCCCCEEEEECCCEEEEECCCCEEEEHHHHHHHHHHCCCCCCEECCCCEEE
IHLVNTFVNDRTYELRGEKIVIPGMAKVLSTLLNNNIKQSTGVNVLSEISSRQQLKNVSR
EEEEHHHHCCCEEEECCCEEEECCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHC
MPPFPGAEEDDDLQVEKIISTAGAPETDDIQIIAYPDTNSLLVKGTVSQVDFIEKLVATL
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHH
DIPKRHIELSLWIIDIDKTDLEQLGADWSGTIKIGSSLSASFNNSGSISTLDGTQFIATI
CCCCCEEEEEEEEEECCCHHHHHHCCCCCCEEEECCCCCCCCCCCCCEEEECCHHHHHHH
QALAQKRRAAVVARPVVLTQENIPAIFDNNRTFYTKLVGERTAELDEVTYGTMISVLPRF
HHHHHHHHHHHEECCEEEECCCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
AARNQIELLLNIEDGNEINSDKTNVDDLPQVGRTLISTIARVPQGKSLLIGGYTRDTNTY
HCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCC
ESRKIPILGSIPFIGKLFGYEGTNANNIVRVFLIEPREIDERMMNNANEAAVDARAITQQ
CCCCCCEEECCCHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHCCCCHHHHHHHHHHHH
MAKNKEINDELLQKWIKTYLNREVVGG
HHCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7868245; 7997169; 11677609 [H]