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The map label for this gene is cadC [H]

Identifier: 209695912

GI number: 209695912

Start: 2673304

End: 2674932

Strand: Reverse

Name: cadC [H]

Synonym: VSAL_I2494

Alternate gene names: 209695912

Gene position: 2674932-2673304 (Counterclockwise)

Preceding gene: 209695914

Following gene: 209695910

Centisome position: 80.45

GC content: 38.55

Gene sequence:

>1629_bases
ATGGTCGGATTATGTTTTCAAATTAATGACTGGACTCTCGTCATTGAAGAAAATAAATTATATCGCCAAGATAGGGAAGT
CTCGGTTGAACCTCGTTTAGTTAATTTGCTTCGTTTTTTAGCCCAACATTCCGGTGAAGTATTTTGCCGTGATGAATTAA
TACAACATGTTTGGGATGGTGCGTTCGTCACTGATCAAGTTGTCACTCAATCTATTTTTGAATTACGCAAGATATTAAGA
GATGGGCGTTTAGATAACGCGAGATACCTTGTGACCGTGCCAAAACGTGGTTATAAGCTTGTTGCTGACACTCAACTCGT
TAATTTTGAAGAGACAGAGTTTTGGAAACCTTGTGACTATTCTAAAACGGTAATCTCTTCAGCGTTAAATTATGCAGAAT
CAGGGCATGCAGCTCACGAGCTTGTTGATGAGAAAGTAACAACAACAGAGCATGATCTTTCTTTTCCATCAGGCCCACTA
ACCCGTGCTATCACGACAATATCGAAAGATGTTGAAAAAGAAAAAAATAAACAGGGGGCAAGCTTTAACTCTTTCCATCG
TTGGAAACTACTCGCTTTTGATGCTTTTCTTGTTTGTATTTTAATAGCAGTAATTATGTCGACAACGTATCAACACACCA
GTACACACATTACAAAAGCGATCGATATCGATTTAATCGAATTTACGTTTCATGCAAGCCGTAATCAAAAAGATGAAACG
GAATTTCTTGCTGATGGGATAAGCCAAAAATTAATGGCAGATTTAGCCAGTGTTGGTAATTATCGTGTTCAATTAGATAA
AACCGCCTTTACGACTGGGATTTTACCTGGGAAAGCGGTGGATGTACGTGTTGAAGAGCAGCAAAATAAAACCTATTTAG
ATGTAGAGTATCGCAGCAATACATCCAATAAAGTGTTGTTTAGTCGTCAATATCGAATGACGCCATCCAATCTTGAGCGT
GTCTTACGTCAATCGTCTTTTGATTTAATGAACGCACTGGGTGTTACTGTTTCTGAAGCACAGATGGACGAATTAATGAT
TGGCTTACCTAAAGAGGAAGGGTTGCTAGAGGTATTGATTCAAGCAAATCATTATATCAATCAACCGGATCCTCGATTGT
TTGAGCAAGGCATACGACTGTTAGAGAAAATATCATCAGAAGAACCTGATAATGGGTATATTTTGGCTGAATTATATATT
GCTTATAATGCATTTTCAGCACTTAACCCTGAGCTTGAATTGAGCGATAACACCATGAAAATTGATAATTTAAGTCAAGA
TTTGGTGGGCAAATACGGGGTTGCAACAGATGAAATATGGCCTGCGCGTATTTATGAAGCATTAGCAATGAATGCCATTA
AACAAGATGATAAAGAAGCGGCTCAAAAATACCTTACGCATGCTTTTGCGCGCAGAGAGTCAGCTTTCTCATACATTCTT
GAAGGAAAGCTTGCGGAGCTGAATGGGAATTTAGATAAAGCGGGGGACGCTTATAGTCGAGCGTTCTTTATGGATACGTC
TCTAGAAACGTACATGTTAAGTGAGAACTTAGCGTTTTACAGTGATCTAGAAACCGTGGCTTATTTTATGTATAGAGCCG
TAAAGCCAAGTGAAGTTCGTTTAATGTAA

Upstream 100 bases:

>100_bases
ATCTCTTTTATGAATCGTATCAATATAAATAGATAATCTTTATTTTTTGAGATGCATAAACTGCTTATATTAATAACGAT
TTAACACCAATGAGTATCTT

Downstream 100 bases:

>100_bases
ATGACAAATAACGGATAACAAAAAGCCCGTAGTACTCAGGACTATGGGCTTTTTTATTTTACGAGAGAATAAAGTATTTA
CACTTTCTTTTTCTCTGGAT

Product: DNA-binding transcriptional activator CadC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MVGLCFQINDWTLVIEENKLYRQDREVSVEPRLVNLLRFLAQHSGEVFCRDELIQHVWDGAFVTDQVVTQSIFELRKILR
DGRLDNARYLVTVPKRGYKLVADTQLVNFEETEFWKPCDYSKTVISSALNYAESGHAAHELVDEKVTTTEHDLSFPSGPL
TRAITTISKDVEKEKNKQGASFNSFHRWKLLAFDAFLVCILIAVIMSTTYQHTSTHITKAIDIDLIEFTFHASRNQKDET
EFLADGISQKLMADLASVGNYRVQLDKTAFTTGILPGKAVDVRVEEQQNKTYLDVEYRSNTSNKVLFSRQYRMTPSNLER
VLRQSSFDLMNALGVTVSEAQMDELMIGLPKEEGLLEVLIQANHYINQPDPRLFEQGIRLLEKISSEEPDNGYILAELYI
AYNAFSALNPELELSDNTMKIDNLSQDLVGKYGVATDEIWPARIYEALAMNAIKQDDKEAAQKYLTHAFARRESAFSYIL
EGKLAELNGNLDKAGDAYSRAFFMDTSLETYMLSENLAFYSDLETVAYFMYRAVKPSEVRLM

Sequences:

>Translated_542_residues
MVGLCFQINDWTLVIEENKLYRQDREVSVEPRLVNLLRFLAQHSGEVFCRDELIQHVWDGAFVTDQVVTQSIFELRKILR
DGRLDNARYLVTVPKRGYKLVADTQLVNFEETEFWKPCDYSKTVISSALNYAESGHAAHELVDEKVTTTEHDLSFPSGPL
TRAITTISKDVEKEKNKQGASFNSFHRWKLLAFDAFLVCILIAVIMSTTYQHTSTHITKAIDIDLIEFTFHASRNQKDET
EFLADGISQKLMADLASVGNYRVQLDKTAFTTGILPGKAVDVRVEEQQNKTYLDVEYRSNTSNKVLFSRQYRMTPSNLER
VLRQSSFDLMNALGVTVSEAQMDELMIGLPKEEGLLEVLIQANHYINQPDPRLFEQGIRLLEKISSEEPDNGYILAELYI
AYNAFSALNPELELSDNTMKIDNLSQDLVGKYGVATDEIWPARIYEALAMNAIKQDDKEAAQKYLTHAFARRESAFSYIL
EGKLAELNGNLDKAGDAYSRAFFMDTSLETYMLSENLAFYSDLETVAYFMYRAVKPSEVRLM
>Mature_542_residues
MVGLCFQINDWTLVIEENKLYRQDREVSVEPRLVNLLRFLAQHSGEVFCRDELIQHVWDGAFVTDQVVTQSIFELRKILR
DGRLDNARYLVTVPKRGYKLVADTQLVNFEETEFWKPCDYSKTVISSALNYAESGHAAHELVDEKVTTTEHDLSFPSGPL
TRAITTISKDVEKEKNKQGASFNSFHRWKLLAFDAFLVCILIAVIMSTTYQHTSTHITKAIDIDLIEFTFHASRNQKDET
EFLADGISQKLMADLASVGNYRVQLDKTAFTTGILPGKAVDVRVEEQQNKTYLDVEYRSNTSNKVLFSRQYRMTPSNLER
VLRQSSFDLMNALGVTVSEAQMDELMIGLPKEEGLLEVLIQANHYINQPDPRLFEQGIRLLEKISSEEPDNGYILAELYI
AYNAFSALNPELELSDNTMKIDNLSQDLVGKYGVATDEIWPARIYEALAMNAIKQDDKEAAQKYLTHAFARRESAFSYIL
EGKLAELNGNLDKAGDAYSRAFFMDTSLETYMLSENLAFYSDLETVAYFMYRAVKPSEVRLM

Specific function: Required for Pcad induction, a promoter upstream of cadB that is responsible for the pH-regulated expression of cadA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790576, Length=540, Percent_Identity=25.1851851851852, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR011990
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 61852; Mature: 61852

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGLCFQINDWTLVIEENKLYRQDREVSVEPRLVNLLRFLAQHSGEVFCRDELIQHVWDG
CEEEEEEECCEEEEEECCHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHCC
AFVTDQVVTQSIFELRKILRDGRLDNARYLVTVPKRGYKLVADTQLVNFEETEFWKPCDY
CHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEECCEEECCCCCCCCCCCCC
SKTVISSALNYAESGHAAHELVDEKVTTTEHDLSFPSGPLTRAITTISKDVEKEKNKQGA
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
SFNSFHRWKLLAFDAFLVCILIAVIMSTTYQHTSTHITKAIDIDLIEFTFHASRNQKDET
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEEEEEEEECCCCCCHHH
EFLADGISQKLMADLASVGNYRVQLDKTAFTTGILPGKAVDVRVEEQQNKTYLDVEYRSN
HHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHCCCCCCEEEEEEECCCCCEEEEEEECCC
TSNKVLFSRQYRMTPSNLERVLRQSSFDLMNALGVTVSEAQMDELMIGLPKEEGLLEVLI
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCEECHHHHHHHHCCCCCCCCHHHHHH
QANHYINQPDPRLFEQGIRLLEKISSEEPDNGYILAELYIAYNAFSALNPELELSDNTMK
HHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHCCCCEEECCCEEE
IDNLSQDLVGKYGVATDEIWPARIYEALAMNAIKQDDKEAAQKYLTHAFARRESAFSYIL
ECCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
EGKLAELNGNLDKAGDAYSRAFFMDTSLETYMLSENLAFYSDLETVAYFMYRAVKPSEVR
CCCHHCCCCCCCCCCCHHHHEEEEECCCHHHEECCCCHHHHHHHHHHHHHHHCCCCCCEE
LM
CC
>Mature Secondary Structure
MVGLCFQINDWTLVIEENKLYRQDREVSVEPRLVNLLRFLAQHSGEVFCRDELIQHVWDG
CEEEEEEECCEEEEEECCHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHCC
AFVTDQVVTQSIFELRKILRDGRLDNARYLVTVPKRGYKLVADTQLVNFEETEFWKPCDY
CHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEECCEEECCCCCCCCCCCCC
SKTVISSALNYAESGHAAHELVDEKVTTTEHDLSFPSGPLTRAITTISKDVEKEKNKQGA
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
SFNSFHRWKLLAFDAFLVCILIAVIMSTTYQHTSTHITKAIDIDLIEFTFHASRNQKDET
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEEEEEEEECCCCCCHHH
EFLADGISQKLMADLASVGNYRVQLDKTAFTTGILPGKAVDVRVEEQQNKTYLDVEYRSN
HHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHCCCCCCEEEEEEECCCCCEEEEEEECCC
TSNKVLFSRQYRMTPSNLERVLRQSSFDLMNALGVTVSEAQMDELMIGLPKEEGLLEVLI
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCEECHHHHHHHHCCCCCCCCHHHHHH
QANHYINQPDPRLFEQGIRLLEKISSEEPDNGYILAELYIAYNAFSALNPELELSDNTMK
HHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHCCCCEEECCCEEE
IDNLSQDLVGKYGVATDEIWPARIYEALAMNAIKQDDKEAAQKYLTHAFARRESAFSYIL
ECCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
EGKLAELNGNLDKAGDAYSRAFFMDTSLETYMLSENLAFYSDLETVAYFMYRAVKPSEVR
CCCHHCCCCCCCCCCCHHHHEEEEECCCHHHEECCCCHHHHHHHHHHHHHHHCCCCCCEE
LM
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370290; 7610040; 9278503 [H]