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The map label for this gene is cdsA [H]

Identifier: 209695846

GI number: 209695846

Start: 2593115

End: 2593954

Strand: Reverse

Name: cdsA [H]

Synonym: VSAL_I2422

Alternate gene names: 209695846

Gene position: 2593954-2593115 (Counterclockwise)

Preceding gene: 209695847

Following gene: 209695845

Centisome position: 78.01

GC content: 38.33

Gene sequence:

>840_bases
TTGAAACAGCGTATAATTACAGCCCTTATTTTAGCTCCTCTAGTTATTGCCGGTATTTTCATGCTGCCAATGCAAGGTTT
TTTAATCGCGATTATGGCCATTACATTGATTGGTTTTTGGGAGTGGACTCAATTTACTGAGTCAAAATCTCGTTATATAG
CTATTATTCCTTCAATTGCTGCATTAGCGGCTTCATTTGTATTTCTCCCTACTTCAACGCTTGAATTAGCAATCCCATCT
GATAGTCATTATATGATGCTCTTAGTTGGTTCGATTTGGTGGTTGATCGCTTCAGGCTTAGTGCTTACCTTTCCTAACAG
CAAAAAAATGTGGCAAAACAATCTACTTTTAAAACATCTTTTTGGTTGGCTAACGATGATCCCATTCTTATGGAGTATTT
TATTACTTCGTGCTGATAACTATGCGTTTGATGGTTATTATGGGGCAAAACTCGTGCTGTTAGTTTGCCTGTTTGTATGG
GCAGCCGATAGTGGCGCTTATTTTGCTGGAAAAACATTTGGTAAACGAAAAATGTCACCTGCAGTTAGTCCAAATAAAAC
GATCGAAGGGTTGATTGGCGGGATCATCACTGCAATTATTATTGGTTGGGGAGCGGCAAGCGCTTTTGAGATCAAATTTG
ATAGTACCGCTGCGATGTTAGGTATTTTTATTGCTACCATCATTATTTCAGTACTTGGTGATCTTGTTGAAAGTATGTTT
AAACGAGCATCTGGTATTAAAGATAGTGGAACTATCATTCCTGGGCACGGTGGTATTTTAGACCGTATTGATAGTTTAAC
GGCTGCCTTTCCTGTATTCGCATTTTTATATCTCTTTTAG

Upstream 100 bases:

>100_bases
TTTAGCGAATGCAGTTGCTTGGTTTGTTAGTCGAGAAAGACGATTTGGTTGTACCGGTGAGCAAATCCAAGCTCTTATGA
ACGAAAAGGATCGATAAAGT

Downstream 100 bases:

>100_bases
TCATTCTTCAGCTCTTTACGTAGAGCAACATAAAAAATGATAGGTTTAATACGGCAGATAGTATGATCTGCCGCTTTTCT
TTCTTACTTTCATCATGGTC

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MKQRIITALILAPLVIAGIFMLPMQGFLIAIMAITLIGFWEWTQFTESKSRYIAIIPSIAALAASFVFLPTSTLELAIPS
DSHYMMLLVGSIWWLIASGLVLTFPNSKKMWQNNLLLKHLFGWLTMIPFLWSILLLRADNYAFDGYYGAKLVLLVCLFVW
AADSGAYFAGKTFGKRKMSPAVSPNKTIEGLIGGIITAIIIGWGAASAFEIKFDSTAAMLGIFIATIIISVLGDLVESMF
KRASGIKDSGTIIPGHGGILDRIDSLTAAFPVFAFLYLF

Sequences:

>Translated_279_residues
MKQRIITALILAPLVIAGIFMLPMQGFLIAIMAITLIGFWEWTQFTESKSRYIAIIPSIAALAASFVFLPTSTLELAIPS
DSHYMMLLVGSIWWLIASGLVLTFPNSKKMWQNNLLLKHLFGWLTMIPFLWSILLLRADNYAFDGYYGAKLVLLVCLFVW
AADSGAYFAGKTFGKRKMSPAVSPNKTIEGLIGGIITAIIIGWGAASAFEIKFDSTAAMLGIFIATIIISVLGDLVESMF
KRASGIKDSGTIIPGHGGILDRIDSLTAAFPVFAFLYLF
>Mature_279_residues
MKQRIITALILAPLVIAGIFMLPMQGFLIAIMAITLIGFWEWTQFTESKSRYIAIIPSIAALAASFVFLPTSTLELAIPS
DSHYMMLLVGSIWWLIASGLVLTFPNSKKMWQNNLLLKHLFGWLTMIPFLWSILLLRADNYAFDGYYGAKLVLLVCLFVW
AADSGAYFAGKTFGKRKMSPAVSPNKTIEGLIGGIITAIIIGWGAASAFEIKFDSTAAMLGIFIATIIISVLGDLVESMF
KRASGIKDSGTIIPGHGGILDRIDSLTAAFPVFAFLYLF

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=282, Percent_Identity=45.0354609929078, Blast_Score=219, Evalue=1e-58,
Organism=Escherichia coli, GI1787677, Length=115, Percent_Identity=44.3478260869565, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 30549; Mature: 30549

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQRIITALILAPLVIAGIFMLPMQGFLIAIMAITLIGFWEWTQFTESKSRYIAIIPSIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHH
ALAASFVFLPTSTLELAIPSDSHYMMLLVGSIWWLIASGLVLTFPNSKKMWQNNLLLKHL
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHH
FGWLTMIPFLWSILLLRADNYAFDGYYGAKLVLLVCLFVWAADSGAYFAGKTFGKRKMSP
HHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCC
AVSPNKTIEGLIGGIITAIIIGWGAASAFEIKFDSTAAMLGIFIATIIISVLGDLVESMF
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
KRASGIKDSGTIIPGHGGILDRIDSLTAAFPVFAFLYLF
HHHCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKQRIITALILAPLVIAGIFMLPMQGFLIAIMAITLIGFWEWTQFTESKSRYIAIIPSIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHH
ALAASFVFLPTSTLELAIPSDSHYMMLLVGSIWWLIASGLVLTFPNSKKMWQNNLLLKHL
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHH
FGWLTMIPFLWSILLLRADNYAFDGYYGAKLVLLVCLFVWAADSGAYFAGKTFGKRKMSP
HHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCC
AVSPNKTIEGLIGGIITAIIIGWGAASAFEIKFDSTAAMLGIFIATIIISVLGDLVESMF
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
KRASGIKDSGTIIPGHGGILDRIDSLTAAFPVFAFLYLF
HHHCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]