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The map label for this gene is msrB [H]

Identifier: 209695317

GI number: 209695317

Start: 1985842

End: 1986246

Strand: Direct

Name: msrB [H]

Synonym: VSAL_I1850

Alternate gene names: 209695317

Gene position: 1985842-1986246 (Clockwise)

Preceding gene: 209695314

Following gene: 209695319

Centisome position: 59.72

GC content: 38.77

Gene sequence:

>405_bases
ATGAATCAATCAAAATCATTTTCTGACTTTACAAACGAAGATTGGAAAAGTGAGTTAACCGACGAAGAATTTGTGGTTTG
TCGACAAAAAGGCACAGAAGCGCCTTTTTCAGGAAAGCTTTTACAGAATAAGGCGACAGGGAATTATGCGTGTACCTGTT
GTCATGTGGATTTGTTTTCATCAGAGAATAAATACGATTCTGGTTGTGGATGGCCAAGCTTTGATGAACCATTAAATACG
CAGGTTATTCGATATATAAAAGACAATAGCCATGGCATGGCGCGAGTAGAGATTCGATGTGCCCGCTGTGATAGTCATTT
AGGGCATGTATTTAATGATGGTCCTAAAACGACCGGAGAGCGTTTTTGTGTTAACTCTATTTCTCTACGCTTTAAAGGTA
AATAA

Upstream 100 bases:

>100_bases
TTTTGGGCTAGCGGTAAAATTACTTTGGCAAAGTATGTGCTACAACGATAAGACTTAGCAAGGTTTAATTTAAATATGTA
ACAAAGGAGGGGTTATTAAA

Downstream 100 bases:

>100_bases
AAAATAGAGAAATAACAGGGAGGAGATACCGATAATTCCTCTCTGTTTTGTCATCACTAATGATTACTGTGAGTCGTTAT
TTATTGTCGGAAGCATTGAA

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MNQSKSFSDFTNEDWKSELTDEEFVVCRQKGTEAPFSGKLLQNKATGNYACTCCHVDLFSSENKYDSGCGWPSFDEPLNT
QVIRYIKDNSHGMARVEIRCARCDSHLGHVFNDGPKTTGERFCVNSISLRFKGK

Sequences:

>Translated_134_residues
MNQSKSFSDFTNEDWKSELTDEEFVVCRQKGTEAPFSGKLLQNKATGNYACTCCHVDLFSSENKYDSGCGWPSFDEPLNT
QVIRYIKDNSHGMARVEIRCARCDSHLGHVFNDGPKTTGERFCVNSISLRFKGK
>Mature_134_residues
MNQSKSFSDFTNEDWKSELTDEEFVVCRQKGTEAPFSGKLLQNKATGNYACTCCHVDLFSSENKYDSGCGWPSFDEPLNT
QVIRYIKDNSHGMARVEIRCARCDSHLGHVFNDGPKTTGERFCVNSISLRFKGK

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI117606353, Length=133, Percent_Identity=49.6240601503759, Blast_Score=137, Evalue=2e-33,
Organism=Homo sapiens, GI37620216, Length=122, Percent_Identity=45.0819672131148, Blast_Score=130, Evalue=3e-31,
Organism=Homo sapiens, GI301336164, Length=122, Percent_Identity=45.0819672131148, Blast_Score=130, Evalue=3e-31,
Organism=Homo sapiens, GI301336162, Length=122, Percent_Identity=45.0819672131148, Blast_Score=130, Evalue=3e-31,
Organism=Homo sapiens, GI73089054, Length=122, Percent_Identity=45.0819672131148, Blast_Score=130, Evalue=3e-31,
Organism=Homo sapiens, GI7706511, Length=103, Percent_Identity=37.8640776699029, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788077, Length=119, Percent_Identity=61.3445378151261, Blast_Score=163, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI17553450, Length=137, Percent_Identity=45.985401459854, Blast_Score=133, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI115532676, Length=136, Percent_Identity=47.0588235294118, Blast_Score=132, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6319816, Length=140, Percent_Identity=45, Blast_Score=108, Evalue=2e-25,
Organism=Drosophila melanogaster, GI221378664, Length=120, Percent_Identity=47.5, Blast_Score=125, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24645799, Length=120, Percent_Identity=47.5, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI45553335, Length=120, Percent_Identity=47.5, Blast_Score=124, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21356369, Length=120, Percent_Identity=47.5, Blast_Score=124, Evalue=1e-29,
Organism=Drosophila melanogaster, GI221378662, Length=127, Percent_Identity=44.8818897637795, Blast_Score=123, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24645801, Length=131, Percent_Identity=43.5114503816794, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24645804, Length=131, Percent_Identity=43.5114503816794, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 15147; Mature: 15147

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
6.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQSKSFSDFTNEDWKSELTDEEFVVCRQKGTEAPFSGKLLQNKATGNYACTCCHVDLFS
CCCCCCCCCCCCCCHHHHCCCCCEEEEECCCCCCCCCCCEECCCCCCCEEEEEEEEEECC
SENKYDSGCGWPSFDEPLNTQVIRYIKDNSHGMARVEIRCARCDSHLGHVFNDGPKTTGE
CCCCCCCCCCCCCCCCCCCHHEEEEEECCCCCEEEEEEEEECCCCCCCHHCCCCCCCCCC
RFCVNSISLRFKGK
EEEEECEEEEEECC
>Mature Secondary Structure
MNQSKSFSDFTNEDWKSELTDEEFVVCRQKGTEAPFSGKLLQNKATGNYACTCCHVDLFS
CCCCCCCCCCCCCCHHHHCCCCCEEEEECCCCCCCCCCCEECCCCCCCEEEEEEEEEECC
SENKYDSGCGWPSFDEPLNTQVIRYIKDNSHGMARVEIRCARCDSHLGHVFNDGPKTTGE
CCCCCCCCCCCCCCCCCCCHHEEEEEECCCCCEEEEEEEEECCCCCCCHHCCCCCCCCCC
RFCVNSISLRFKGK
EEEEECEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]