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The map label for this gene is lolA

Identifier: 209695309

GI number: 209695309

Start: 1977479

End: 1978075

Strand: Direct

Name: lolA

Synonym: VSAL_I1842

Alternate gene names: 209695309

Gene position: 1977479-1978075 (Clockwise)

Preceding gene: 209695308

Following gene: 209695310

Centisome position: 59.47

GC content: 38.53

Gene sequence:

>597_bases
GTGAAGAAAATTTTATTATCATTGTGTTTTTTAAGTTCTGTTGCTTTTGCTTCTCCACAAGGTGAATTAACGGATCGTTT
GAATCAAAATAAAGGTTTTGAAGCGTCATTTACACAAAAAGTGTTGAGCCCTGAAGGGGATGTATTGATGCAAGGCGAAG
GGGATGTGAAAATTTTGCGTCCTAACTTGTTCCGCTGGCATACTCAAACTCCGGATGAAAACCTATTAGTGACCGATGGA
AAAACATTGTGGTACTACAATCCATTTGTAGAACAAGTGACTCTTATGGGATTAGATCAAGCGACAACTCAAACTCCTTT
TGTTTTATTAACACGCAATAAAGCGTCTGATTGGGATAACTACTCAGTAGCTCAAAACGGTGATGCATTTACGGTTTCAC
CAAAATCAGATTCTGCTATAAAAAGTGAATTCATCGTTCGTATTCAACCGTCAGGTAAAGTAACGGGGTTTTCAGTTGTA
GAGCAAGATGGGCAGCGTAGCGATTTTAATTTCACAACGTTTGAAGCGAAAAAGCCAGCCCAATCTAATTTTATGTTCAC
TGTCCCTGATGGTGTAGATATTGATGATCAGCGTTAA

Upstream 100 bases:

>100_bases
TAGTAAGTACTCCGGGCCATAATGGTAACCGTGAAGTGATTGCACCGCCTCCTGTAGGTTTGGGCGATTAATTGTCTTGT
TTAAATTGAGATTATTTATA

Downstream 100 bases:

>100_bases
GGTCTTACTTAATGCGAAATCATGTTTAGAATAAAAGGATAAACGTGAGTAATTTCAGTTTAGATTTTTCAGCAGGGGAC
GATTTTCGTCCCCTTGCTGC

Product: outer-membrane lipoprotein carrier protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MKKILLSLCFLSSVAFASPQGELTDRLNQNKGFEASFTQKVLSPEGDVLMQGEGDVKILRPNLFRWHTQTPDENLLVTDG
KTLWYYNPFVEQVTLMGLDQATTQTPFVLLTRNKASDWDNYSVAQNGDAFTVSPKSDSAIKSEFIVRIQPSGKVTGFSVV
EQDGQRSDFNFTTFEAKKPAQSNFMFTVPDGVDIDDQR

Sequences:

>Translated_198_residues
MKKILLSLCFLSSVAFASPQGELTDRLNQNKGFEASFTQKVLSPEGDVLMQGEGDVKILRPNLFRWHTQTPDENLLVTDG
KTLWYYNPFVEQVTLMGLDQATTQTPFVLLTRNKASDWDNYSVAQNGDAFTVSPKSDSAIKSEFIVRIQPSGKVTGFSVV
EQDGQRSDFNFTTFEAKKPAQSNFMFTVPDGVDIDDQR
>Mature_198_residues
MKKILLSLCFLSSVAFASPQGELTDRLNQNKGFEASFTQKVLSPEGDVLMQGEGDVKILRPNLFRWHTQTPDENLLVTDG
KTLWYYNPFVEQVTLMGLDQATTQTPFVLLTRNKASDWDNYSVAQNGDAFTVSPKSDSAIKSEFIVRIQPSGKVTGFSVV
EQDGQRSDFNFTTFEAKKPAQSNFMFTVPDGVDIDDQR

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family

Homologues:

Organism=Escherichia coli, GI145693108, Length=202, Percent_Identity=44.5544554455446, Blast_Score=187, Evalue=5e-49,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): LOLA_ALISL (B6ENN3)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002263238.1
- GeneID:   6987415
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I1842
- HOGENOM:   HBG688940
- OMA:   VDIDDQR
- ProtClustDB:   PRK00031
- HAMAP:   MF_00240
- InterPro:   IPR004564
- InterPro:   IPR018323
- TIGRFAMs:   TIGR00547

Pfam domain/function: PF03548 LolA

EC number: NA

Molecular weight: Translated: 22175; Mature: 22175

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILLSLCFLSSVAFASPQGELTDRLNQNKGFEASFTQKVLSPEGDVLMQGEGDVKILR
CHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHCCCCCEEEECCCCEEEEC
PNLFRWHTQTPDENLLVTDGKTLWYYNPFVEQVTLMGLDQATTQTPFVLLTRNKASDWDN
CCEEEEECCCCCCCEEEECCCEEEEECHHHHHEEEECCCCCCCCCCEEEEECCCCCCCCC
YSVAQNGDAFTVSPKSDSAIKSEFIVRIQPSGKVTGFSVVEQDGQRSDFNFTTFEAKKPA
EEEECCCCEEEECCCCCCCCCEEEEEEECCCCCEEEEEEEECCCCCCCCCEEEEECCCCC
QSNFMFTVPDGVDIDDQR
CCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MKKILLSLCFLSSVAFASPQGELTDRLNQNKGFEASFTQKVLSPEGDVLMQGEGDVKILR
CHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHCCCCCEEEECCCCEEEEC
PNLFRWHTQTPDENLLVTDGKTLWYYNPFVEQVTLMGLDQATTQTPFVLLTRNKASDWDN
CCEEEEECCCCCCCEEEECCCEEEEECHHHHHEEEECCCCCCCCCCEEEEECCCCCCCCC
YSVAQNGDAFTVSPKSDSAIKSEFIVRIQPSGKVTGFSVVEQDGQRSDFNFTTFEAKKPA
EEEECCCCEEEECCCCCCCCCEEEEEEECCCCCEEEEEEEECCCCCCCCCEEEEECCCCC
QSNFMFTVPDGVDIDDQR
CCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA