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The map label for this gene is mltC [H]

Identifier: 209694963

GI number: 209694963

Start: 1562147

End: 1563268

Strand: Direct

Name: mltC [H]

Synonym: VSAL_I1446

Alternate gene names: 209694963

Gene position: 1562147-1563268 (Clockwise)

Preceding gene: 209694961

Following gene: 209694964

Centisome position: 46.98

GC content: 39.93

Gene sequence:

>1122_bases
ATGAAAAACTACTGGCTTTCTCTTTTGGTTTGCTTATCTACTGTTTCTTGCACCCCTATTTTTTCTGGCTCAAACACTTC
CCTAAGACCTGGGACAACTGTCTGTGATCAATGCAGTAGTATAAACACATCTGCCAGTTCAAAACCGACAAGCGAACAGC
TTGCAAACCTAGCGTCTCAAATACACAGTAAATGGGGCGACAAAGAGTTTTTAGAAGCCGGTAAACACCGTTATGTTAAG
TATCTTGATGGTTACCGCACTCGCGCGCACATCGATTTTGATAAAGGTAAGATTTATGTTTCAACCGTCTCACAATATGA
GCCAAAAGAGACACTCAAAAAAGCGATTGTGAGCACCATTCTTATGCCTGCCGATCCGTCACACGTTGATTTATTCAGTG
ATAAATCGATTCCATTGCGTGGGCGTCCATTTTTGCTTGGTCAAATTAAAGACCAAGACAATAAAAATATTGAGTGGCCA
TGGCGTGCGGATCGTTATGCAACCTATTTAATTGATAATCATTTAAAATCAAAACCGATTAAAAGAGGGAACGCGTATTA
CGTTGAGATCTCAATGGTCAAAGACCACCTTGAGCAACGCGAGTTTCAATACGCTGATTTGATTAAGAAAGCGTCAAAAG
AATACGACATTTCCATTGATTTGATTTACGCCATTATCAAAACAGAAAGCAGCTTTAATCCTTATGCTGTCAGTCACGCA
GGCGCGTATGGGTTAATGCAAGTGATCCCAAAAACGGCTGGGGCAGATGTCTTTAGTTTAGTGAAAAAGAAACCAGGTAT
TCCAACCAAAGAATACTTGTTTAACCCAGCGAATAATATTGATACTGGAACCGCATACTTTTATATATTGAAGAACCGTT
ACTTACGAGATATTAGCCACGCAACAAATAAGCATTACAGCATGATCTCGGCATACAACGGTGGCTCAGGTGGTGTGTTT
TCAACGTTTGATCCAAATCGTACGAAAGCGATCAGCGAAATAAACCGTTTACAGCCAAATCAATTGTATTGGGCATTAAC
GAATAAACACCCTAAAGCTGAAGCGCGTCGATATTTAGAAAAAGTATTGGCGTTTCAAAGAGAATTTAATGAGAAAGCAT
AG

Upstream 100 bases:

>100_bases
CAAACTCTGTGTAAAATACGCCTCCTTATCGGCTAACATGCTATACGTAATCTATCCCAGTATATTGATAAATAAACTCA
ATATGCGACTTAGGACATAA

Downstream 100 bases:

>100_bases
CGCTCAATCTTCGTTACTATTGATAATTAATTGGTGTGTATAAATTGAAATATTTATTCGTTGTTCTCATGTGTTTTTAT
TCTTCTATGTCATTAGCGAT

Product: membrane-bound lytic murein transglycosylase C

Products: N-Acetylmuramic Acid Residues; N-Acetylglucosamine Residues [C]

Alternate protein names: Murein hydrolase C [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKNYWLSLLVCLSTVSCTPIFSGSNTSLRPGTTVCDQCSSINTSASSKPTSEQLANLASQIHSKWGDKEFLEAGKHRYVK
YLDGYRTRAHIDFDKGKIYVSTVSQYEPKETLKKAIVSTILMPADPSHVDLFSDKSIPLRGRPFLLGQIKDQDNKNIEWP
WRADRYATYLIDNHLKSKPIKRGNAYYVEISMVKDHLEQREFQYADLIKKASKEYDISIDLIYAIIKTESSFNPYAVSHA
GAYGLMQVIPKTAGADVFSLVKKKPGIPTKEYLFNPANNIDTGTAYFYILKNRYLRDISHATNKHYSMISAYNGGSGGVF
STFDPNRTKAISEINRLQPNQLYWALTNKHPKAEARRYLEKVLAFQREFNEKA

Sequences:

>Translated_373_residues
MKNYWLSLLVCLSTVSCTPIFSGSNTSLRPGTTVCDQCSSINTSASSKPTSEQLANLASQIHSKWGDKEFLEAGKHRYVK
YLDGYRTRAHIDFDKGKIYVSTVSQYEPKETLKKAIVSTILMPADPSHVDLFSDKSIPLRGRPFLLGQIKDQDNKNIEWP
WRADRYATYLIDNHLKSKPIKRGNAYYVEISMVKDHLEQREFQYADLIKKASKEYDISIDLIYAIIKTESSFNPYAVSHA
GAYGLMQVIPKTAGADVFSLVKKKPGIPTKEYLFNPANNIDTGTAYFYILKNRYLRDISHATNKHYSMISAYNGGSGGVF
STFDPNRTKAISEINRLQPNQLYWALTNKHPKAEARRYLEKVLAFQREFNEKA
>Mature_373_residues
MKNYWLSLLVCLSTVSCTPIFSGSNTSLRPGTTVCDQCSSINTSASSKPTSEQLANLASQIHSKWGDKEFLEAGKHRYVK
YLDGYRTRAHIDFDKGKIYVSTVSQYEPKETLKKAIVSTILMPADPSHVDLFSDKSIPLRGRPFLLGQIKDQDNKNIEWP
WRADRYATYLIDNHLKSKPIKRGNAYYVEISMVKDHLEQREFQYADLIKKASKEYDISIDLIYAIIKTESSFNPYAVSHA
GAYGLMQVIPKTAGADVFSLVKKKPGIPTKEYLFNPANNIDTGTAYFYILKNRYLRDISHATNKHYSMISAYNGGSGGVF
STFDPNRTKAISEINRLQPNQLYWALTNKHPKAEARRYLEKVLAFQREFNEKA

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI87082191, Length=320, Percent_Identity=45.3125, Blast_Score=290, Evalue=9e-80,
Organism=Escherichia coli, GI87081855, Length=164, Percent_Identity=37.1951219512195, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI87082441, Length=174, Percent_Identity=32.7586206896552, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 42418; Mature: 42418

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00922 TRANSGLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNYWLSLLVCLSTVSCTPIFSGSNTSLRPGTTVCDQCSSINTSASSKPTSEQLANLASQ
CCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHH
IHSKWGDKEFLEAGKHRYVKYLDGYRTRAHIDFDKGKIYVSTVSQYEPKETLKKAIVSTI
HHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHH
LMPADPSHVDLFSDKSIPLRGRPFLLGQIKDQDNKNIEWPWRADRYATYLIDNHLKSKPI
HCCCCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEHHHCCHHCCCC
KRGNAYYVEISMVKDHLEQREFQYADLIKKASKEYDISIDLIYAIIKTESSFNPYAVSHA
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEHHCCCCCCCEEEHHC
GAYGLMQVIPKTAGADVFSLVKKKPGIPTKEYLFNPANNIDTGTAYFYILKNRYLRDISH
CHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHH
ATNKHYSMISAYNGGSGGVFSTFDPNRTKAISEINRLQPNQLYWALTNKHPKAEARRYLE
HCCCCEEEEEEEECCCCCEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
KVLAFQREFNEKA
HHHHHHHHHCCCC
>Mature Secondary Structure
MKNYWLSLLVCLSTVSCTPIFSGSNTSLRPGTTVCDQCSSINTSASSKPTSEQLANLASQ
CCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHH
IHSKWGDKEFLEAGKHRYVKYLDGYRTRAHIDFDKGKIYVSTVSQYEPKETLKKAIVSTI
HHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHH
LMPADPSHVDLFSDKSIPLRGRPFLLGQIKDQDNKNIEWPWRADRYATYLIDNHLKSKPI
HCCCCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEHHHCCHHCCCC
KRGNAYYVEISMVKDHLEQREFQYADLIKKASKEYDISIDLIYAIIKTESSFNPYAVSHA
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEHHCCCCCCCEEEHHC
GAYGLMQVIPKTAGADVFSLVKKKPGIPTKEYLFNPANNIDTGTAYFYILKNRYLRDISH
CHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHH
ATNKHYSMISAYNGGSGGVFSTFDPNRTKAISEINRLQPNQLYWALTNKHPKAEARRYLE
HCCCCEEEEEEEECCCCCEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
KVLAFQREFNEKA
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA